Results 81 to 90 of about 709,638 (304)

Dual‐Peptide Nanoplatform: Mesoporous Silica Nanoparticles Functionalized With a Cell‐Penetrating Peptide and Loaded With Rationally Designed Antimicrobial Peptides for Tuberculosis Therapy

open access: yesAdvanced Healthcare Materials, EarlyView.
Machine learning–guided engineering of a plectasin‐derived peptide yields DC05, a potent antimycobacterial candidate. Encapsulation into tuftsin‐functionalized mesoporous silica nanoparticles enhances intracellular delivery, stability, and activity against Mycobacterium tuberculosis while maintaining low cytotoxicity and minimal hemolysis. The combined
Christian S. Carnero Canales   +12 more
wiley   +1 more source

GENETIC STRUCTURE AND DRUG RESISTANCE OF MYCOBACTERIUM TUBERCULOSIS POPULATION IN THE CIVIL SECTOR OF THE KYRGYZ REPUBLIC

open access: yesТуберкулез и болезни лёгких, 2014
The genetic structure of drug-resistant and drug-susceptible Mycobacterium tuberculosis (MBT) circulating in the civil sector of the Kyrgyz Republic was analyzed.
Zh. T. Isakova   +3 more
doaj  

Performance of QuantiFERON TB in a student population at low risk of tuberculosis

open access: yesJournal of Infection in Developing Countries, 2011
This item has no abstract. Follow the links below to access the full text.
Paola Molicotti   +2 more
doaj   +1 more source

Optimization of rTDMH as a Reagent Toward Improving the Sensitivity of the RT-PCR Based Diagnosis for Mycobacterium Tuberculosis [PDF]

open access: yes, 2012
Current diagnostic tools being used for tuberculosis lack the speed and sensitivity necessary to successfully combat the current tuberculosis epidemic.
Bhatti, Alexandra
core  

Respiratory Organ‐on‐a‐Chip for Disease Modeling: From Architecture to Functional Integration

open access: yesAdvanced Healthcare Materials, EarlyView.
Respiratory organ‐on‐a‐chip (ROC) models capture key mechanical and cellular cues of the human respiratory system, enabling quantitative dissection of disease mechanisms. This review links ROC architectures to disease modeling, functional integration, and commercialization, and proposes a decision framework that aligns model complexity with mechanistic
Jinzhuo Hu   +4 more
wiley   +1 more source

Definition desired mode ultraviolet radiation, which prevent Mycobacterium tuberculosis survival and conversion to L-forms

open access: yesAnnals of Mechnikov's Institute, 2020
Bactericidal effect of ultraviolet (UV) rays was first described over 100 years ago. UV was used in hospitals from 1930 and in 1936 was first used to sterilize the air in the operating room. The maximum bactericidal effect occurs in the region 254-257 nm
T Moiseenko, A Volyanski, A Kovaleva
doaj  

Structure and function of the mycobacterial transcription initiation complex with the essential regulator RbpA

open access: yeseLife, 2017
RbpA and CarD are essential transcription regulators in mycobacteria. Mechanistic analyses of promoter open complex (RPo) formation establish that RbpA and CarD cooperatively stimulate formation of an intermediate (RP2) leading to RPo; formation of RP2 ...
Elizabeth A Hubin   +7 more
doaj   +1 more source

SITE-SPECIFIC RECOMBINATION OF THE MYCOBACTERIUM TUBERCULOSISPROPHAGE-LIKE ELEMENT PHIRV1 [PDF]

open access: yes, 2004
The site-specific recombination systems of bacteriophages and other mobile elements fall into two categories that are named for the integrase protein that catalyzes integration and excision of the phage genome.
Bibb, Lori Ann
core  

Bacteria‐Responsive Nanostructured Drug Delivery Systems for Targeted Antimicrobial Therapy

open access: yesAdvanced Materials, EarlyView.
Bacteria‐responsive nanocarriers are designed to release antimicrobials only in the presence of infection‐specific cues. This selective activation ensures drug release precisely at the site of infection, avoiding premature or indiscriminate release, and enhancing efficacy.
Guillermo Landa   +3 more
wiley   +1 more source

DRUG RESISTANCE OF STRAINS OF M. TUBERCULOSIS, ISOLATED FROM PULMONARY TUBERCULOSIS PATIENTS IN VLADIMIR REGION IN 2013

open access: yesТуберкулез и болезни лёгких, 2015
The study presents the analysis of drug susceptibility of tuberculosis mycobacteria isolated from pulmonary tuberculosis patients by the moment of their registration in 2013 on the territory of Vladimir region. Totally 574 pulmonary tuberculosis patients
E. S. Dyuzhik   +4 more
doaj  

Home - About - Disclaimer - Privacy