Results 101 to 110 of about 709,638 (304)

Macrophage Extracellular Traps in Immunity and Cancer

open access: yesAdvanced Science, EarlyView.
As a macrophage‐mediated innate defense mechanism, the dysregulated release of METs drives chronic inflammation and influences tumor progression. Furthermore, METs exhibit a functional duality within the tumor microenvironment, capable of both promoting and suppressing tumor development.
Junyao Li   +5 more
wiley   +1 more source

PRECLINICAL STUDIES OF THE SPECIFIC ACTIVITY OF THE NEW ANTITUBERCULOSIS DRUG THIOZONIDE

open access: yesТуберкулез и болезни лёгких, 2014
In vitro and in vivo preclinical studies of the antituberculosis activity of thiozonide designed at the ZAO “Farn-Sintez” (Moscow) were conducted at the Central Research of Tuberculosis, Russian Academy of Medical Sciences.
I. V. Bocharova   +5 more
doaj   +1 more source

Consumed by Abdominal Distention

open access: yes
Arthritis Care &Research, EarlyView.
Abimbola Fadairo‐Azinge   +3 more
wiley   +1 more source

Lymphoid‐Tissue‐on‐Chip Recapitulates Human Antibody Responses In Vitro

open access: yesAdvanced Science, EarlyView.
The presented lymphoid‐tissue‐on‐chip system allows culture of primary human tonsil cells at organotypic high density under perfusion for up to 4 weeks, emulates immune response to soluble vaccines and vaccination via peripheral antigen‐presenting cells and represents a useful tool to assess cellular interactions during homeostasis, immune responses ...
Claudia Teufel   +15 more
wiley   +1 more source

EXPRESSION OF GENES ENCODING IMMUNOPROTEASOME SUBUNITS INDUCIBLE BY MACROPHAGES INFECTED WITH M. bovis BGC AND M. Tuberculosis H37RV

open access: yesТуберкулез и болезни лёгких, 2014
To study the effect of M. bovis BCG vaccine strain and virulent laboratory M. tuberculosis H37Rv strain on the expression of macrophageinducible immunoproteasome subunits, a real-time reverse-transcription polymerase chain reaction technique using cDNA ...
S. N. Andreevskaya   +4 more
doaj  

Complications after BCG vaccination in a big city

open access: yesТуберкулез и болезни лёгких, 2016
Complications after specific prevention of tuberculosis for the last 10 years have been analyzed using the example of a big city. The frequency of severe complications (BCG-ostitis) made 0.004% and the frequency of minor complications (lymphadenitis ...
T. A. Sevostyanova   +2 more
doaj   +1 more source

Membrane Type 1 Matrix Metalloproteinase Regulates Monocyte Migration and Collagen Destruction in Tuberculosis [PDF]

open access: yes, 2015
Tuberculosis (TB) remains a global pandemic and drug resistance is rising. Multicellular granuloma formation is the pathological hallmark of Mycobacterium tuberculosis infection.
Brilha, S   +8 more
core   +2 more sources

Mass‐Produced and High‐Performance Nanowell Biosensor Fabricated via Semiconductor Manufacturing for Rapid and Accurate COVID‐19 Diagnosis in the Clinical Field

open access: yesAdvanced Science, EarlyView.
A semiconductor‐fabricated nanowell biosensor enables rapid, scalable, and highly reproducible detection of SARS‐CoV‐2 antigens from nasal swabs within ∼10 minutes. Clinical validation in 249 retrospective and 243 prospective patient samples demonstrates high sensitivity and specificity, minimal cross‐reactivity, and robust batch‐to‐batch ...
Yoo Min Park   +11 more
wiley   +1 more source

Discovery and Biosynthesis of the Novel Glycotetrapeptide Antibiotic Biffamycin A

open access: yesAngewandte Chemie, EarlyView.
Genetic de‐regulation of a silent biosynthetic pathway allowed isolation and characterisation of a novel glycopeptide antibiotic named biffamycin A, which harbours unprecedented 5‐chloro‐4‐methoxy tryptophan and 3R‐hydroxy(α‐D‐mannoysl)‐D‐lysine moieties and is bioactive against MRSA and VRSA.
Michael W. Brigham   +11 more
wiley   +2 more sources

Resuscitation of latent M. tuberculosis?

open access: yes, 2017
Current assays for determining the presence of M. tuberculosis infection, such as an interferon gamma release assay (IGRA) or tuberculin skin test (TST), cannot predict which infected individuals will develop active tuberculosis.
Panaiotov, Stefan   +8 more
openaire   +1 more source

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