Results 101 to 110 of about 709,638 (304)
Macrophage Extracellular Traps in Immunity and Cancer
As a macrophage‐mediated innate defense mechanism, the dysregulated release of METs drives chronic inflammation and influences tumor progression. Furthermore, METs exhibit a functional duality within the tumor microenvironment, capable of both promoting and suppressing tumor development.
Junyao Li +5 more
wiley +1 more source
PRECLINICAL STUDIES OF THE SPECIFIC ACTIVITY OF THE NEW ANTITUBERCULOSIS DRUG THIOZONIDE
In vitro and in vivo preclinical studies of the antituberculosis activity of thiozonide designed at the ZAO “Farn-Sintez” (Moscow) were conducted at the Central Research of Tuberculosis, Russian Academy of Medical Sciences.
I. V. Bocharova +5 more
doaj +1 more source
Consumed by Abdominal Distention
Arthritis Care &Research, EarlyView.
Abimbola Fadairo‐Azinge +3 more
wiley +1 more source
Lymphoid‐Tissue‐on‐Chip Recapitulates Human Antibody Responses In Vitro
The presented lymphoid‐tissue‐on‐chip system allows culture of primary human tonsil cells at organotypic high density under perfusion for up to 4 weeks, emulates immune response to soluble vaccines and vaccination via peripheral antigen‐presenting cells and represents a useful tool to assess cellular interactions during homeostasis, immune responses ...
Claudia Teufel +15 more
wiley +1 more source
To study the effect of M. bovis BCG vaccine strain and virulent laboratory M. tuberculosis H37Rv strain on the expression of macrophageinducible immunoproteasome subunits, a real-time reverse-transcription polymerase chain reaction technique using cDNA ...
S. N. Andreevskaya +4 more
doaj
Complications after BCG vaccination in a big city
Complications after specific prevention of tuberculosis for the last 10 years have been analyzed using the example of a big city. The frequency of severe complications (BCG-ostitis) made 0.004% and the frequency of minor complications (lymphadenitis ...
T. A. Sevostyanova +2 more
doaj +1 more source
Membrane Type 1 Matrix Metalloproteinase Regulates Monocyte Migration and Collagen Destruction in Tuberculosis [PDF]
Tuberculosis (TB) remains a global pandemic and drug resistance is rising. Multicellular granuloma formation is the pathological hallmark of Mycobacterium tuberculosis infection.
Brilha, S +8 more
core +2 more sources
A semiconductor‐fabricated nanowell biosensor enables rapid, scalable, and highly reproducible detection of SARS‐CoV‐2 antigens from nasal swabs within ∼10 minutes. Clinical validation in 249 retrospective and 243 prospective patient samples demonstrates high sensitivity and specificity, minimal cross‐reactivity, and robust batch‐to‐batch ...
Yoo Min Park +11 more
wiley +1 more source
Discovery and Biosynthesis of the Novel Glycotetrapeptide Antibiotic Biffamycin A
Genetic de‐regulation of a silent biosynthetic pathway allowed isolation and characterisation of a novel glycopeptide antibiotic named biffamycin A, which harbours unprecedented 5‐chloro‐4‐methoxy tryptophan and 3R‐hydroxy(α‐D‐mannoysl)‐D‐lysine moieties and is bioactive against MRSA and VRSA.
Michael W. Brigham +11 more
wiley +2 more sources
Resuscitation of latent M. tuberculosis?
Current assays for determining the presence of M. tuberculosis infection, such as an interferon gamma release assay (IGRA) or tuberculin skin test (TST), cannot predict which infected individuals will develop active tuberculosis.
Panaiotov, Stefan +8 more
openaire +1 more source

