Results 51 to 60 of about 378,588 (317)

Elevated levels of matrix metalloproteinases reflect severity and extent of disease in tuberculosis-diabetes co-morbidity and are predominantly reversed following standard anti-tuberculosis or metformin treatment

BMC Infectious Diseases, 2018
Background Matrix metalloproteinases (MMPs) are considered to be key mediators of tuberculosis (TB) pathology but their role in tuberculosis – diabetes comorbidity (TB-DM) is not well understood.
Nathella P. Kumar, Kadar Moideen, Vijay Viswanathan, Basavaradhya S. Shruthi, Shanmugam Sivakumar, Pradeep A. Menon, Hardy Kornfeld, Subash Babu   +7 more
doaj   +1 more source

Human immunodeficiency virus increases the risk of tuberculosis due to recent re-infection in individuals with latent infection. [PDF]

, 2010
BACKGROUND: Human immunodeficiency virus associated tuberculosis (TB) disease can follow reactivation of latent Mycobacterium tuberculosis infection or recent (re-)infection with M. tuberculosis. If contemporary TB cases share identical M.
Fine, P.E.M., Glynn, J.R., Mallard, K., Sichali, L., Crampin, A.C., Mallard, K, French, N, Houben, RMGJ, Malema, S, Glynn, JR, Sichali, L, Houben, R.M.G.J, Malema, S., Crampin, AC, Fine, PEM, French, N.   +15 more
core  

Genomic Diversity among Beijing and non-Beijing Mycobacterium tuberculosis Isolates from Myanmar

, 2008
Background: The Beijing family of Mycobacterium tuberculosis is dominant in countries in East Asia. Genomic polymorphisms are a source of diversity within the M. tuberculosis genome and may account for the variation of virulence among M.
Hinds Jason, Grewal, HM, Butcher, PD, Stavrum Ruth, Stavrum, R, Bø, TH, Ruth Stavrum, Valvatne, H, Trond H Bø, Jonassen, I, Philip D Butcher, Valvatne Håvard, Bø Trond H., Hinds, J, Butcher Philip D., Jonassen Inge, Inge Jonassen, Jason Hinds, Håvard Valvatne, Harleen M S Grewal, Grewal Harleen M. S.   +20 more
core   +1 more source

Association Between Smoking and Tuberculosis Infection: A Population Survey in a High Tuberculosis Incidence Area [PDF]

, 2005
Associations between smoking and tuberculosis disease including death from tuberculosis have been reported, but there are few reports on the influence of smoking on the risk of developing Mycobacterium tuberculosis infection. The aim of this study was to
Beyers, N., van Lill, S.W.P., Enarson, D.A., Borgdorff, M. W., Verver, S, Lombard, C.J, den Boon, S., Lombard, C. J., Beyers, N, Verver, S., Boon den, S, van Lill, S. W. P., Enarson, D. A., Bateman, E. D., Enarson, D.A, Bateman, E.D, Borgdorff, M.W., Borgdorff, M.W, Lombard, C.J., LIll van, P, Bateman, E.D.   +20 more
core   +1 more source

Movement Disorders in Aicardi–Goutières Syndrome and Response to Immunomodulation

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT This study characterizes movement disorders and treatment responses in seven children with Aicardi–Goutières syndrome (AGS). We retrospectively evaluated motor phenotypes, neuroimaging, and interferon signatures in patients treated with baricitinib or anifrolumab. Spasticity affected all patients, while dystonia was present in 4/7.
Enrique Gonzalez Saez‐Diez, Monica Ferrer Socorro, Kathryn Yang, Nicole Battaglia, Zainab Zaman, Mariko Bennett, Adeline Vanderver, Pui Y. Lee, Lauren A. Henderson, Milena M. Andzelm, Darius Ebrahimi‐Fakhari   +10 more
wiley   +1 more source

Cost-effectiveness in the diagnosis of tuberculosis: choices in developing countries

Journal of Infection in Developing Countries, 2014
Tuberculosis remains one of the major causes of global death from a single infectious agent. This situation is worsened by the HIV/AIDS pandemic because one-third of HIV/AIDS patients are co-infected with Mycobacterium tuberculosis.
Paola Molicotti, Alessandra Bua, Stefania Zanetti   +2 more
doaj   +1 more source

Comparative Effectiveness and Safety of Inebilizumab Versus Rituximab in AQP4‐IgG‐Positive NMOSD

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Rituximab (anti‐CD20, RTX) and inebilizumab (anti‐CD19, INE) represent B‐cell‐depleting therapies used for aquaporin‐4 antibody‐positive (AQP4‐IgG+) neuromyelitis optica spectrum disorder (NMOSD); however, direct comparative evidence remains limited.
Jie Lin, Binbin Xue, Dewei Xie, Jia Li, Juyuan Pan, Lanbing Zhu, Qiaowen Tong, Jing Lin, Ruofan Zhu, Xu Zhang, Junhui Xia, Xiang Li   +11 more
wiley   +1 more source

Performance of QuantiFERON TB in a student population at low risk of tuberculosis

Journal of Infection in Developing Countries, 2011
This item has no abstract. Follow the links below to access the full text.
Paola Molicotti, Alessandra Bua, Stefania Zanetti   +2 more
doaj   +1 more source

Distinct Persistence Fate of Mycobacterium tuberculosis in Various Types of Cells

mSystems, 2021
Mycobacterium tuberculosis can invade different cells with distinct persistence fates because cells are equipped with different host restriction factors. However, the underlying mechanisms remain elusive.
Xi Chen, Xiaojian Cao, Yingying Lei, Aikebaier Reheman, Wei Zhou, Bing Yang, Weipan Zhang, Weize Xu, Shuang Dong, Rohit Tyagi, Zhen F. Fu, Gang Cao   +11 more
doaj   +1 more source

Nitrobenzoates and Nitrothiobenzoates with Activity against M. tuberculosis

Microorganisms, 2023
Esters of weak acids have shown improved antimycobacterial activity over the corresponding free acids and nitro benzoates in particular have previously shown to have a very intriguing activity. To expand the potential of nitro-derivatives of benzoic acid as antimycobacterial drugs and explore the effects of various structural features on the activity ...
João P. Pais, Olha Antoniuk, Raquel Freire, David Pires, Emília Valente, Elsa Anes, Luis Constantino   +6 more
openaire   +4 more sources