Results 31 to 40 of about 378,588 (317)

Culture-independent detection and characterisation of Mycobacterium tuberculosis and M. africanum in sputum samples using shotgun metagenomics on a benchtop sequencer [PDF]

, 2014
Tuberculosis remains a major global health problem. Laboratory diagnostic methods that allow effective, early detection of cases are central to management of tuberculosis in the individual patient and in the community.
Emma L. Doughty, Martin Antonio, Sergeant, Martin J, Pallen, Mark J, Pallen, Mark J., Emma L Doughty, Ifedayo M.O Adetifa, Mark J. Pallen, Martin J. Sergeant, Doughty, Emma L, Sergeant, Martin J., Ifedayo, Adetifa M. O., Ifedayo Adetifa, Martin J Sergeant, Doughty, Emma L., Antonio, Martin, Adetifa, Ifedayo, Mark J Pallen   +17 more
core   +1 more source

Detection of Mycobacterium tuberculosis on stool specimens by PCR among patients with pulmonary tuberculosis

Journal of Family Medicine and Primary Care, 2022
Background: To detect Mycobacterium tuberculosis on stool specimens by polymerase chain reaction (PCR) among patients with pulmonary tuberculosis. Detection of M.
Vasudha Kesarwani, N P Singh, Bineeta Kashyap, Amit Kumar   +3 more
doaj   +1 more source

Tuberculosis diagnosis using immunodominant, secreted antigens of Mycobacterium tuberculosis

, 2013
Summary Tuberculosis (TB) remains a major public health concern in most low-income countries. Hence, rapid and sensitive TB diagnostics play an important role in detecting and preventing the disease. In addition to established diagnostic methods, several
Aliya, Bekmurzayeva, Sypabekova, Marzhan, Kanayeva, Damira, Bekmurzayeva, Aliya   +3 more
core   +1 more source

In vitro Tuberculosis Granuloma Model in M. tuberculosis H37Rv

Jurnal Biosains Pascasarjana, 2023
M. tuberculosis is a bacterium that has many evasion mechanisms against the immune system, one of them is the formation of granulomas which is beneficial for the bacteria’s survival. The granuloma structure is useful for limiting the spread of M. tuberculosis and localizing infection, also considered as part of M.
openaire   +1 more source

The human immune response to tuberculosis and its treatment: a view from the blood. [PDF]

, 2015
The immune response upon infection with the pathogen Mycobacterium tuberculosis is poorly understood, hampering the discovery of new treatments and the improvements in diagnosis.
van Helden, Paul, van Helden, P., Cliff, Jacqueline M, Kaufmann, Stefan HE, O'Garra, Anne, Kaufmann, S., McShane, H., O'Garra, A., Cliff, J., McShane, Helen   +9 more
core   +1 more source

Reproductive disorders in the experimental modeling of tuberculosis

Туберкулез и болезни лёгких, 2020
For experimental modeling of tuberculosis, animals of various species are used, each of which has its own advantages and disadvantages. Specific characteristics of animal genetics and immunology during the development of tuberculosis in the experiment ...
S. I. Kayukova, N. V. Sterzhanova, B. V. Nikonenko   +2 more
doaj   +1 more source

Profiling the immune response to Mycobacterium tuberculosis Beijing family infection: a perspective from the transcriptome

Virulence, 2021
Tuberculosis continues to be an important public health problem. Particularly considering Beijing-family strains of Mycobacterium tuberculosis, which have been associated with drug-resistance and hypervirulence.
Cerezo-Cortés María Irene, Rodríguez-Castillo Juan Germán, López-Leal Gamaliel, Mata-Espinosa Dulce Adriana, Bini Estela Isabel, Marquina–Casitllo Brenda Nohemí, Barrios Payan Jorge, Zatarain-Barrón Zyanya Lucía, Bobadilla del Valle Myriam, Cornejo-Granados F, Ochoa-Leyva Adrian, Murcia Martha Isabel, Hernández-Pando Rogelio   +12 more
doaj   +1 more source

Tongue Ulcer as a Manifestation of Secondary HIV-Associated Multidrug-Resistant Tuberculosis

Туберкулез и болезни лёгких, 2022
Tuberculosis of the tongue is one of the rare localizations of extrapulmonary tuberculosis. The article presents a clinical case of secondary tuberculous glossitis with concurrent multidrug-resistant pulmonary tuberculosis in a 35-year-old HIV-infected ...
A. V. Kukurika, I. A. Iurovskaia, E. I. Iurovskaia   +2 more
doaj   +1 more source

Distribution and transmission of mycobacterium tuberculosis complex lineages among children in peri-urban Kampala, Uganda [PDF]

, 2015
To gain insight into the transmission of tuberculosis (TB) in peri-urban Kampala-Uganda, we performed a household contact study using children as a surrogate for recent transmission of Mycobacterium tuberculosis (MTB).
Eddie M. Wampande, Kathleen Eisenach, Mary Nsereko, Wampande, Eddie M., W. Henry Boom, Mayanja, Harriet K., Mupere, Ezekiel, Gagneux, Sebastien, Eisenach, Kathleen, Joloba, Moses L., Moses L. Joloba, Ezekiel Mupere, Nsereko, Mary, Sebastien Gagneux, Harriet K. Mayanja, null null, Devan Jaganath, Boom, W. Henry, Jaganath, Devan, Tuberculosis Research Unit,   +19 more
core   +1 more source

THE SEARCH OF OPTIMAL COMBINATION OF ANTIGENS FOR SEROLOGICAL DIAGNOSTICS OF TUBERCULOSIS

Инфекция и иммунитет, 2014
. The four chimeric recombinant antigens CBD-CFP10, CBD-ESAT6, ESAT6-CFP10 and CBD-P38 contained aminoacid sequences of full-size proteins ESAT6, CFP10 and matured protein P38 of M.
E. V. Vasilyeva, V. N. Verbov, A. B. Beklemishev, A. L. Mamaev, A. O. Tsyrul’nikov, T. A. Stepanenko, V. B. Ivanovskii, S. V. Lapin, Areg A. Totolian   +8 more
doaj   +1 more source