Results 31 to 40 of about 24,558,315 (312)

Elevated levels of matrix metalloproteinases reflect severity and extent of disease in tuberculosis-diabetes co-morbidity and are predominantly reversed following standard anti-tuberculosis or metformin treatment

BMC Infectious Diseases, 2018
Background Matrix metalloproteinases (MMPs) are considered to be key mediators of tuberculosis (TB) pathology but their role in tuberculosis – diabetes comorbidity (TB-DM) is not well understood.
Nathella P. Kumar, Kadar Moideen, Vijay Viswanathan, Basavaradhya S. Shruthi, Shanmugam Sivakumar, Pradeep A. Menon, Hardy Kornfeld, Subash Babu   +7 more
doaj   +1 more source

Probing Host Pathogen Cross-Talk by Transcriptional Profiling of Both Mycobacterium tuberculosis and Infected Human Dendritic Cells and Macrophages. [PDF]

, 2008
BACKGROUND: Transcriptional profiling using microarrays provides a unique opportunity to decipher host pathogen cross-talk on the global level. Here, for the first time, we have been able to investigate gene expression changes in both Mycobacterium ...
Waddell, Simon, Castagnoli, PR, Mattia Pelizzola (20247), Castagnoli, Paola Ricciardi, Pelizzola Mattia, Foti, M, Maria Foti, Butcher, Philip, Neyrolles, Olivier, Neyrolles, O, Antoine Tanne, Simon J Waddell, Olivier Neyrolles, Pelizzola, M, Tailleux, L, Simon J. Waddell, Antoine Tanne (272975), Philip D Butcher (16047203), Maria Foti (20249), Neil G. Stoker, Stoker Neil G., Waddell, SJ, Tailleux Ludovic, Tailleux, Ludovic, Gicquel, Brigitte, Simon Waddell (4462816), Castagnoli Paola Ricciardi, Brigitte Gicquel, Philip D Butcher, Tanne Antoine, Alessandra Mortellaro (272973), Mortellaro, A, Gicquel Brigitte, Stoker, Neil, Philip D. Butcher, Butcher, PD, Tanne, Antoine, Olivier Neyrolles (72204), Tanne, A, Mortellaro, Alessandra, Paola Ricciardi Castagnoli (16048310), Ludovic Tailleux, Michael Withers (272974), Neyrolles Olivier, Withers Michael, Foti, Maria, Waddell Simon J., Stoker, NG, Michael Withers, Pelizzola, Mattia, Mortellaro Alessandra, Brigitte Gicquel (31454), Ludovic Tailleux (72195), Neil G Stoker (16048313), Alessandra Mortellaro, Neil G Stoker, Foti Maria, Gicquel, B, Butcher Philip D., Withers, M, Mattia Pelizzola, Paola Ricciardi Castagnoli, Withers, Michael, Waddel S.J., Withers M., Neyrolles O., Tanne A., Tailleux L., Foti M., Stoker N.G., Butcher P.D., Pelizzola M., Mortellaro A., Gicquel B., Castagnoli P.R.   +74 more
core   +1 more source

Cost-effectiveness in the diagnosis of tuberculosis: choices in developing countries

Journal of Infection in Developing Countries, 2014
Tuberculosis remains one of the major causes of global death from a single infectious agent. This situation is worsened by the HIV/AIDS pandemic because one-third of HIV/AIDS patients are co-infected with Mycobacterium tuberculosis.
Paola Molicotti, Alessandra Bua, Stefania Zanetti   +2 more
doaj   +1 more source

Acute and persistent Mycobacterium tuberculosis infections depend on the thiol peroxidase TpX. [PDF]

, 2009
The macrophage is the natural niche of Mycobacterium tuberculosis infection. In order to combat oxidative and nitrosative stresses and persist in macrophages successfully, M. tuberculosis is endowed with a very efficient antioxidant complex.
Hu, Y, Yanmin Hu, Anthony R M Coates, Anthony R. M. Coates, Coates, AR   +4 more
core   +2 more sources

Performance of QuantiFERON TB in a student population at low risk of tuberculosis

Journal of Infection in Developing Countries, 2011
This item has no abstract. Follow the links below to access the full text.
Paola Molicotti, Alessandra Bua, Stefania Zanetti   +2 more
doaj   +1 more source

Development and optimization of a gas chromatography/mass spectrometry method for the analysis of thermochemolytic degradation products of phthiocerol dimycocerosate waxes found in Mycobacterium tuberculosis. [PDF]

, 2013
RATIONALE: The phthiocerol dimycocerosates (PDIMs) are certain stable and hydrophobic waxes found in the cell membrane of Mycobacterium tuberculosis, bacteria that cause an infectious disease of growing concern worldwide.
O'Sullivan, Denise M., Minnikin, David E, O'Sullivan, Denise M, Minnikin, David E., Wright, Ian P., McNerney, Ruth, Lee, Oona CY, Morgan, Geraint H, Pillinger, Colin T., Nicoara, Simona C., Lee, Oona C. Y., Morgan, Geraint H., Pillinger, Collin T, Nicoara, Simona C, Wright, Ian P   +14 more
core   +1 more source

PhyTB: Phylogenetic tree visualisation and sample positioning for M. tuberculosis. [PDF]

, 2015
BACKGROUND: Phylogenetic-based classification of M. tuberculosis and other bacterial genomes is a core analysis for studying evolutionary hypotheses, disease outbreaks and transmission events.
Pain, Arnab, Mohareb, Fady R, Taane G Clark, Campino, Susana, Nick Furnham, Clark, Taane G., Benavente, Ernest D., McNerney, Ruth, Glynn, Judith R., Ruth McNerney, Glynn, Judith R, Furnham, Nick, Fady R Mohareb, Benavente, Ernest D, Susana Campino, Francesc Coll, Judith R Glynn, Mohareb, Fady R., Ernest D Benavente, Arnab Pain, Coll, Francesc, Clark, Taane G   +21 more
core   +2 more sources

Optimization of Lyophilized LAMP and RT-PCR Reaction Mixes for Detection of Tuberculosis

The EuroBiotech Journal, 2020
Undoubtedly, one of the most infectious diseases in the world is tuberculosis. Key factor for tuberculosis control is to prevent possible contagion with rapid diagnosis and effective treatment.
Agel Esra, Sagcan Hasan
doaj   +1 more source

Tongue Ulcer as a Manifestation of Secondary HIV-Associated Multidrug-Resistant Tuberculosis

Туберкулез и болезни лёгких, 2022
Tuberculosis of the tongue is one of the rare localizations of extrapulmonary tuberculosis. The article presents a clinical case of secondary tuberculous glossitis with concurrent multidrug-resistant pulmonary tuberculosis in a 35-year-old HIV-infected ...
A. V. Kukurika, I. A. Iurovskaia, E. I. Iurovskaia   +2 more
doaj   +1 more source

HLA-B*35-restricted CD8(+)-T-cell epitope in Mycobacterium tuberculosis Rv2903c.

, 2002
Few human CD8(+) T-cell epitopes in mycobacterial antigens have been described to date. Here we have identified a novel HLA-B*35-restricted CD8(+) T-cell epitope in Mycobacterium tuberculosis Rv2903c based on a reverse immunogenetics approach.
Lukey, Pauline T, Abdulrahman S. Hammond, McAdam, Keith PWJ, Klein, Michèl R, Jaye, Assan, Smith, Steve M, Michèl R. Klein, Assan Jaye, Steve M. Smith, Hammond, Abdulrahman S, Pauline T. Lukey, Keith P. W. J. McAdam   +11 more
core   +1 more source