Results 211 to 220 of about 27,333,880 (308)

CMAISE: Establishing the Longitudinal Multi‐Omics Cohort for Sepsis Precision Medicine

open access: yesMed Research, EarlyView.
ABSTRACT Sepsis remains a leading cause of mortality worldwide due to its profound biological heterogeneity. While multi‐omics approaches offer promise for precision medicine, existing datasets often lack longitudinal granularity or comprehensive clinical integration. We present the Chinese Multi‐omics Advances In Sepsis (CMAISE) cohort, a prospective,
Jie Yang   +36 more
wiley   +1 more source

Alveolar macrophages from persons with HIV mount impaired TNF signaling networks to M. tuberculosis infection. [PDF]

open access: yesNat Commun
Kgoadi K   +7 more
europepmc   +1 more source

Vegetating Lupus Vulgaris in a Child

open access: yes
JEADV Clinical Practice, EarlyView.
Viktor Pushkarenko   +2 more
wiley   +1 more source

Genome‐Wide Assessment Reveals Ancestral Differences in Homozygosity Patterns Potentially Linked to Parkinson's Disease Etiology

open access: yesMovement Disorders, EarlyView.
Abstract Background Recessive genetic variation and extended runs of homozygosity (ROHs) may contribute to the unexplained heritability of Parkinson's disease (PD), particularly in diverse and understudied populations. Objective We conducted the first large‐scale, multi‐ancestral investigation of PD to examine the impact of genome‐wide homozygosity on ...
Kathryn Step   +680 more
wiley   +1 more source

Genome‐wide screen reveals a universal role of ATP in ciprofloxacin tolerance among genetically distinct Escherichia coli persisters

open access: yesmLife, EarlyView.
Abstract Bacterial persisters show tolerance to bactericidal antibiotics and play essential roles in chronic infections; however, the general mechanisms underlying persister formation and antibiotic tolerance remain insufficiently characterized. In this study, the Escherichia coli Keio library was used to identify genes involved in ciprofloxacin ...
Zhenfang Mei   +9 more
wiley   +1 more source

Series 2: Development of a Multiplex Amplicon Next Generation Sequencing Assay for Rapid Assessment of Resistance-Associated Mutations in <i>M. tuberculosis</i> Clinical Cases. [PDF]

open access: yesTrop Med Infect Dis
Cabrera A   +14 more
europepmc   +1 more source

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