Results 231 to 240 of about 27,333,880 (308)

Evidence‐based guideline for clinical practice in the diagnosis, treatment, management, and prevention of recurrent wheezing in infants and toddlers in China

Pediatric Investigation, EarlyView.
ABSTRACT Wheezing is a common respiratory symptom in infants and toddlers, and recurrent wheezing is a significant respiratory disorder affecting this age group. Given the multifactorial etiology of recurrent wheezing, clinical practice lacks standardized diagnostic and therapeutic protocols. Recent years have witnessed substantial progress in clinical
Committee of Pediatrics, China Medical Education Association, Cooperative Group of Asthma, the Subspecialty Group of Respiratory, the Society of Pediatrics, Chinese Medical Association, Pediatric Respiratory Work Committee, Society of Pulmonologists, Chinese Medical Doctor Association, Committee of Pediatrics, Chinese Research Hospital Association, Pediatric Professional Committee of the Chinese Non‐public Medical Institutions Association, Professional Committee of Children's Health and Pharmaceutical Research, China Association of Traditional Chinese Medicine, Children's Safe Medication Branch of China News of Drug Information Association, Pediatric Expert Committee of China Primary Health Care Foundation, China International Medical Foundation   +16 more
wiley   +1 more source

Interred mechanisms of resistance and host immune evasion revealed through network-connectivity analysis of <i>M. tuberculosis</i> complex graph pangenome. [PDF]

mSystems
Espinoza ME, Swing AM, Elghraoui A, Modlin SJ, Valafar F.   +4 more
europepmc   +1 more source

Proteome Analysis of Corynebacterium diphtheriae–Macrophage Interaction

PROTEOMICS, EarlyView.
ABSTRACT Contact of Corynebacterium diphtheriae with macrophages induces adaptations on both bacterial and cellular sides. The study presented here was aiming to shed light on the simultaneous intracellular adaptation of the bacteria and changes in the proteome of the phagocytes in response to the internalization of C. diphtheriae.
Luca Musella, Jens Möller, Christopher Lischer, Julio Vera‐Gonzalez, Jörg Hofmann, Lisa Ott, Andreas Burkovski   +6 more
wiley   +1 more source

Structural and mechanistic study of a novel inhibitor of M. tuberculosis cytochrome bc1:aa3

Lamers M, Verma A, Kim R, Lamprecht D, Pérez CA, Wong S, Veziris N, Aubry A, Bartolomé-Nebreda JM, Carbajo R, Wetzel J.   +10 more
europepmc   +1 more source

Structural and mechanistic study of a novel inhibitor analogue of <i>M. tuberculosis</i> cytochrome bc₁:aa₃. [PDF]

NPJ Drug Discov
Verma AK, Kim RQ, Lamprecht DA, Aguilar-Pérez C, Wong S, Veziris N, Aubry A, Bartolomé-Nebreda JM, Carbajo RJ, Wetzel J, Lamers MH.   +10 more
europepmc   +1 more source

Proteome‐Wide Analysis of Palmitoylated Proteins in Macrophages Reveals Novel Insights Into Early Immune Signaling

PROTEOMICS, EarlyView.
ABSTRACT Protein S‐palmitoylation, a reversible lipid modification, plays critical roles in regulating protein function and localization. However, its comprehensive role in the rapid reprogramming of macrophages during early immune responses remains incompletely understood.
Hyojung Kim, Jiraphorn Issara‐Amphorn, Sung Hwan Yoon, Anirban Banerjee, Aleksandra Nita‐Lazar   +4 more
wiley   +1 more source

Molecular Epidemiology of Isoniazid-resistant <i>M tuberculosis</i> in Port-au-Prince, Haiti. [PDF]

Open Forum Infect Dis
Walsh KF, Lee MH, Chaguza C, Pamphile W, Royal G, Escuyer V, Pape JW, Fitzgerald D, Cohen T, Ocheretina O.   +9 more
europepmc   +1 more source

The frequency of CD38⁺ alveolar macrophages correlates with early control of M. tuberculosis in the murine lung. [PDF]

Nat Commun
Pisu D, Johnston L, Mattila JT, Russell DG.   +3 more
europepmc   +1 more source

Rv0100: An essential acyl carrier protein from M. tuberculosis important in dormancy. [PDF]

PLoS One
Gutka HJ, Bondoc JMG, Patwell R, Khan S, Grzelak EM, Goswami R, Voskuil MI, Movahedzadeh F.   +7 more
europepmc   +1 more source

Metabolic Reprogramming in HIV+ CD4⁺ T-Cells: Implications for Immune Dysfunction and Therapeutic Targets in <i>M. tuberculosis</i> Co-Infection. [PDF]

Metabolites
Ayrga S, Koorsen G.
europepmc   +1 more source