Results 31 to 40 of about 449,265 (199)
Engineering IL‐4 resistant proinflammatory human myeloid cells for cancer immunotherapy
Molecular Oncology, EarlyView.We developed a scalable workflow to generate proinflammatory human myeloid cells. CRISPR/Cas9‐edited CD34+ hematopoietic stem and progenitor cells were expanded and differentiated with M‐CSF. Deletion of STAT6 or STAT6/NFKB1 enhanced macrophage proinflammatory gene expression and cytokine secretion in the presence of IL‐4 while maintaining antibody ...
Theresa Barberi, Alan D. Friedman
wiley +1 more source
Economics and Culture, 2020 Purpose. This study aimed to explore the relationship between organisational justice and commitment and how the combined influence of organisational justice and perceived organisational support (POS) impacts on commitment.
Twumasi Evelyn, Addo Belinda
doaj +1 more source
Spatial heterogeneity of hotspot mutations and clonal relatedness in ovarian endometrioid carcinoma
Molecular Oncology, EarlyView.Spatially resolved analysis revealed heterogeneous distributions of selected cancer‐associated mutations within ovarian endometrioid carcinomas. Shared mutations between paired endometrial and ovarian tumors supported clonal relatedness. These findings highlight the value of sampling multiple tumor regions when interpreting molecular profiles ...
Takahito Ashihara +10 more
wiley +1 more source
First Theoretical Identification of the Magnetic Dipole Moment of the 97.43 keV State in 153Eu
Sakarya Üniversitesi Fen Bilimleri Enstitüsü Dergisi, 2022 Two alternative values, +3.21±0.22 μ_N and-0.52±0.22 μ_N, for the magnetic dipole (M1) moment of the excited [532] 5/2- state at 97.43 keV in 153Eu were reported in the Mossbauer-effect study.
Gamze Hoşgör +3 more
doaj +1 more source
In silico and in vitro exploration of a tyrosinase for biocatalytic production of catechols
FEBS Open Bio, EarlyView.Tyrosinase from Ralstonia pseudosolanacearum is a promising biocatalyst for producing valuable catechols from monophenol substrates. This tyrosinase is uniquely suited to this due to its high monophenolase : diphenolase ratio. We combined in silico docking and in vivo kinetic characterisation of this tyrosinase with 11 industrially relevant monophenols,
James Britton +6 more
wiley +1 more source
FEBS Open Bio, EarlyView.We describe detailed protocols for the purification and preparation of Marchantia polymorpha Auxin Response Factor 2 (MpARF2). This protein is fused to an MBP solubility tag and an mNG fluorescent tag and is purified from Escherichia coli. The presented procedures make it possible to study MpARF2 assemblies, which could arise from phase separation ...
Bas Janssen +5 more
wiley +1 more source
Business Systems Research, 2023 Public opinion about experience and expectation on services that appear on Twitter platforms provides valuable insights into satisfaction and experience.
Saad Nor Hasliza Md +2 more
doaj +1 more source
BCG vaccination potentiates oxidative phosphorylation in neonatal myeloid‐derived suppressor cells
FEBS Open Bio, EarlyView.BCG vaccination enhances oxidative phosphorylation in neonatal MDSCs, impairing their immunosuppressive function. It upregulates electron transport chain genes and mitochondrial activity, increasing ATP and oxygen consumption. Pharmacological OXPHOS inhibition partially restores suppressive capacity, confirming causality.
Yingying Chen, Hui Li
wiley +1 more source
Journal of Economics and ManagementAim/purpose – This study explores the crucial link between the quality of work life (QWL) and subjective well-being (SWB) among aviation industry employees.
Agarwal Shivani +2 more
doaj +1 more source
The Importance of Positive Leadership in the Process of Change on the Example of the Banking Sector
Foundations of Management, 2021 In today's world, the success of modern company in dealing with change depends, to a large extent, on a positive approach toward its knowledge workers.
Morawski Mieczysław +1 more
doaj +1 more source