Impact of Renal Impairment on the Pharmacokinetics of Apremilast and Metabolite M12
Clinical Pharmacology in Drug Development, 2016 AbstractThe pharmacokinetics of apremilast and its major metabolite M12 were evaluated in subjects with varying degrees of renal impairment. Men and women with renal impairment (estimated glomerular filtration rate, 60‒89 mL/min [mild, n = 8], 30‒59 mL/min [moderate, n = 8], or <30 mL/min [severe, n = 8]) or demographically healthy matched (control)
Yong Liu +4 more
semanticscholar +5 more sources
The Luminosity Function and Color‐Magnitude Diagram of the Globular Cluster M12 [PDF]
The Astrophysical Journal, 2004 In this paper we present the V and I luminosity functions and color-magnitude diagrams derived from wide-field (23 arcmin by 23 arcmin) BVI photometry of the intermediate metallicity ([Fe/H]=-1.3) Galactic globular cluster M12. Using observed values (and ranges of values) for the cluster metallicity, reddening, distance modulus, and age we compare ...
Jonathan R. Hargis +2 more
semanticscholar +6 more sources
Cohomology of the Double Cover of the Mathieu Group M12
Journal of Algebra, 2000 Abstract In this paper we calculate the mod two cohomology of the double cover of the Mathieu group M 12 . The starting point is the calculation by Adem, Maginnis and Milgram of the mod two cohomology of M 12 . We use a hypercohomology spectral sequence to determine a differential in the Lyndon-Hochschild-Serre spectral sequence of the central ...
David J. Benson, Jon Carlson
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Tracing Past Human Male Movements in Northern/Eastern Africa and Western Eurasia: New Clues from Y-Chromosomal Haplogroups E-M78 and J-M12 [PDF]
Molecular biology and evolution, 2007 Detailed population data were obtained on the distribution of novel biallelic markers that finely dissect the human Y-chromosome haplogroup E-M78. Among 6,501 Y chromosomes sampled in 81 human populations worldwide, we found 517 E-M78 chromosomes and ...
Fulvio Cruciani +23 more
openalex +2 more sources
Медицинская иммунология, 2014 . In former studies, using an experimental rabbit model of acute post-streptococcal glomerulonephritis (GAS), we have proven a role of M-like Fc-binding streptococcal proteins (IgG FcBPs) for initiating destructive/degenerative lesions of renal glomeruli
L. A. Burova +6 more
doaj +2 more sources
A proper motion study of the globular cluster M12 (NGC 6218) [PDF]
Research in Astronomy and Astrophysics, 2018 16 pages, accepted by RAA on May ...
Ing-Guey Jiang +2 more
openaire +5 more sources
Characterization of T cell epitopes restricted by HLA-DP9 in streptococcal M12 protein. [PDF]
Journal of Immunology, 1995 Interaction of the HLA-DP9 (DPA1*0201/DPB1*0901) molecule and M protein of serotype 12 (SS95/12) streptococci, a main component of the streptococcal cell wall Ag, has been investigated to decipher peptide-binding capacity and T cell activation in the ...
Rui Dong +5 more
openalex +2 more sources
Photometry Results for the Globular Clusters M10 and M12: Extinction Maps, Color-Magnitude Diagrams, and Variable Star Candidates [PDF]
, 2002 We report on photometry results of the equatorial globular clusters (GCs) M10 and M12. These two clusters are part of our sample of GCs which we are probing for the existence of photometrically varying eclipsing binary stars.
Alex Athey +9 more
core +2 more sources
Effect of rifampicin on the growth of RNA bacteriophage M12 [PDF]
FEBS Letters, 1972 Doris Meier, P. H. Hofschneider
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M12-03: Pharmacodynamic separation [PDF]
Journal of Thoracic Oncology, 2007 Angela M. Davies
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