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DirectRM: integrated detection of landscape and crosstalk between multiple RNA modifications using direct RNA sequencing. [PDF]
Zhang Y +10 more
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Quantifying the mRNA epitranscriptome reveals epitranscriptome signatures and roles in cancer. [PDF]
Feng Y +11 more
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The inspiration of methyltransferase in RNA methylation modification for targeted therapy of malignant tumors. [PDF]
Chen X +9 more
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Deficiency of N1-Adenine Methyltransferase Aggravates RNA and Protein Aggregation. [PDF]
Alriquet M +4 more
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tRNA-m1A modification promotes T cell expansion via efficient MYC protein synthesis
Nature Immunology, 2022Naive T cells undergo radical changes during the transition from dormant to hyperactive states upon activation, which necessitates de novo protein production via transcription and translation. However, the mechanism whereby T cells globally promote translation remains largely unknown.
Yongbo Liu +19 more
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Cellular Signalling, 2023
Keratoconjunctivitis is the most common complication of Sjögren's syndrome (SS). It has always been a hot research topic due to its complex pathogenesis. A further understanding of keratoconjunctiva xerosis can be obtained by studying the primary diseases.
Yuxiu, Liu, Jianing, Zhu, Lin, Ding
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Keratoconjunctivitis is the most common complication of Sjögren's syndrome (SS). It has always been a hot research topic due to its complex pathogenesis. A further understanding of keratoconjunctiva xerosis can be obtained by studying the primary diseases.
Yuxiu, Liu, Jianing, Zhu, Lin, Ding
openaire +2 more sources
ACS Chemical Biology
tRNA modifications help maintain tRNA structure and facilitate translation and stress response. Found in all three kingdoms of life, m1A tRNA modification occurs in the T loop of many tRNAs, stabilizes tertiary tRNA structure, and impacts translation.
Marcus Foo +6 more
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tRNA modifications help maintain tRNA structure and facilitate translation and stress response. Found in all three kingdoms of life, m1A tRNA modification occurs in the T loop of many tRNAs, stabilizes tertiary tRNA structure, and impacts translation.
Marcus Foo +6 more
openaire +2 more sources
m1A tRNA modification facilitates rapid T cell proliferation
Nature Immunology, 2022openaire +2 more sources
Comprehensive Analyses of M1A Regulator-Mediated Modification Patterns in Lower-Grade Glioma
2023Kunjian Lei +7 more
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