Results 121 to 130 of about 4,686 (145)

The RNA methylation modification as an immunometabolic regulatory hub in pancreatic cancer: from mechanistic insights to clinical translation perspectives. [PDF]

Mol Cancer
Zhu Y, Ma K, Hao Q, Fu K, Hei F, Sun N, Yin Z, Guo W, Zou H, Tan Z.   +9 more
europepmc   +1 more source

RNA modification-mediated multidimensional crosstalk: a novel perspective on gene expression regulation. [PDF]

Genome Biol
Wang Y, Yang C, Lin R, Ling H, Xu YZ, Wu Q, Zhou Y.   +6 more
europepmc   +1 more source

tRNA modifications in cancer: from molecular mechanisms to clinical translation. [PDF]

Biomark Res
Cheng CH, Wong CC.
europepmc   +1 more source

Selective Preconcentration and Mass Spectrometry Profiling of Charged Extracellular Modified Ribonucleosides by Borate Complexation and Temperature-Assisted Ionic Liquid Microextraction. [PDF]

ACS Meas Sci Au
Floro GM, McCarragher CP, Shih YL, Clark KD.   +3 more
europepmc   +1 more source

Mapping the RNA methylome under drought: techniques, mechanisms, and agricultural implications. [PDF]

Front Plant Sci
Fan X, Zhang Y.
europepmc   +1 more source

m1A RNA Modification in Gene Expression Regulation

Genes, 2022
N1-methyladenosine (m1A) is a prevalent and reversible post-transcriptional RNA modification that decorates tRNA, rRNA and mRNA. Recent studies based on technical advances in analytical chemistry and high-throughput sequencing methods have revealed the crucial roles of m1A RNA modification in gene regulation and biological processes. In this review, we
Tianhua Zhou, Shanshan Xie, Zhou Tianhua   +2 more
exaly   +3 more sources

N 1-methyladenosine (m1A) RNA modification: the key to ribosome control [PDF]

Journal of Biochemistry, 2020
AbstractRNA displays diverse functions in living cells. The presence of various chemical modifications of RNA mediated by enzymes is one of the factors that impart such functional diversity to RNA. Among more than 100 types of RNA modification, N1-methyladenosine (m1A) is found mainly in tRNA and rRNA of many living organisms and is known to be deeply ...
Kazuhiko Igarashi, Shima Hiroki, Igarashi Kazuhiko   +2 more
exaly   +3 more sources

The Impact of m1A Methylation Modification Patterns on Tumor Immune Microenvironment and Prognosis in Oral Squamous Cell Carcinoma [PDF]

International Journal of Molecular Sciences, 2021
N1-methyladenosine (m1A) modification widely participates in the occurrence and progression of numerous diseases. Nevertheless, the potential roles of m1A in the tumor immune microenvironment (TIME) are still not fully understood. Based on 10 m1A methylation regulators, we comprehensively explored the m1A modification patterns in 502 patients with oral
Masahiro Sugimoto, Masanobu Mizuta, Yo Kishimoto   +2 more
exaly   +3 more sources

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tRNA-m1A modification promotes T cell expansion via efficient MYC protein synthesis

Nature Immunology, 2022
Naive T cells undergo radical changes during the transition from dormant to hyperactive states upon activation, which necessitates de novo protein production via transcription and translation. However, the mechanism whereby T cells globally promote translation remains largely unknown.
Yongbo Liu, Jing Zhou, Xiaoyu Li, Xiaoting Zhang, Jintong Shi, Xuefei Wang, Hao Li, Shan Miao, Huifang Chen, Xiaoxiao He, Liting Dong, Gap Ryol Lee, Junke Zheng, Ru-Juan Liu, Bing Su, Youqiong Ye, Richard A. Flavell, Chengqi Yi, Yuzhang Wu, Hua-Bing Li   +19 more
openaire   +2 more sources