Results 111 to 120 of about 1,872,691 (138)

Author response: The landscape of m1A modification and its posttranscriptional regulatory functions in primary neurons

, 2023
Mengfan Hou, Xianfu Yi, Chi Zhang, Qingyang Li, Xueying Li, Lu Lu, Enlin Qi, Mingxin Wu, Lin Qi, Huan Jian, Zhangyang Qi, Yigang Lv, Xiaohong Kong, Mingjun Bi, Shiqing Feng, Hengxing Zhou   +15 more
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Editor's evaluation: The landscape of m1A modification and its posttranscriptional regulatory functions in primary neurons

, 2023
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Decision letter: The landscape of m1A modification and its posttranscriptional regulatory functions in primary neurons

, 2023
openaire   +1 more source

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Prokaryotic RNA N1-Methyladenosine Erasers Maintain tRNA m1A Modification Levels in Streptomyces venezuelae

ACS Chemical Biology
tRNA modifications help maintain tRNA structure and facilitate translation and stress response. Found in all three kingdoms of life, m1A tRNA modification occurs in the T loop of many tRNAs, stabilizes tertiary tRNA structure, and impacts translation ...
Christopher Katanski, Huimin Zhao, Tao Pan   +2 more
exaly   +4 more sources

SeqAlignXGBoost: Sequence Alignment and Feature Selection for m1A Modification Site Identification

Lecture Notes in Computer Science
Quan Zou, Yijie Ding, Zou Quan
exaly   +3 more sources

tRNA-m1A modification promotes T cell expansion via efficient MYC protein synthesis

Nature Immunology, 2022
Naive T cells undergo radical changes during the transition from dormant to hyperactive states upon activation, which necessitates de novo protein production via transcription and translation. However, the mechanism whereby T cells globally promote translation remains largely unknown.
Yongbo Liu, Jing Zhou, Xiaoyu Li, Xiaoting Zhang, Jintong Shi, Xuefei Wang, Hao Li, S. Miao, Huifang Chen, Xiaoxiao He, Liting Dong, G. Lee, Junke Zheng, Rujuan Liu, Bing Su, Youqiong Ye, R. Flavell, C. Yi, Yuzhang Wu, Hua-Bing Li   +19 more
semanticscholar   +3 more sources

N 1-methyladenosine (m1A) RNA modification: the key to ribosome control [PDF]

Journal of Biochemistry, 2020
AbstractRNA displays diverse functions in living cells. The presence of various chemical modifications of RNA mediated by enzymes is one of the factors that impart such functional diversity to RNA. Among more than 100 types of RNA modification, N1-methyladenosine (m1A) is found mainly in tRNA and rRNA of many living organisms and is known to be deeply ...
Kazuhiko Igarashi, Igarashi Kazuhiko, Shima Hiroki   +2 more
exaly   +3 more sources

m1A tRNA modification facilitates rapid T cell proliferation

Nature Immunology, 2022

semanticscholar   +3 more sources

tRNA m1A modification orchestrates STING translation in macrophages to enhance antitumor immunity and CAR-macrophage immunotherapy

Cellular and Molecular Immunology
Hua-Bing Li, Hu Weiguo, Wang Xuefei
exaly   +2 more sources

tRNA m1A modification regulates cholesterol biosynthesis to promote antitumor immunity of CD8+ T cells.

Journal of Experimental Medicine
Activation of CD8+ T cells necessitates rapid metabolic reprogramming to fulfill the substantial biosynthetic demands of effector functions. However, the posttranscriptional mechanisms underpinning this process remain obscure. The transfer RNA (tRNA) N1-methyladenine (m1A) modification, essential for tRNA stability and protein translation, has an ...
Shan Miao, Hao Li, Xiaohan Song, Yongbo Liu, Gaoyang Wang, Chen Kan, Youqiong Ye, Rujuan Liu, Huabing Li   +8 more
semanticscholar   +3 more sources