Results 31 to 40 of about 7,801 (240)

Anti‐M3 Muscarinic Acetylcholine Receptor Autoantibody in the Serum and Saliva of Oral Lichen Planus Patients: A Case‐Control Study [PDF]

Health Science Reports
Background and Aims Oral lichen planus OLP) is a chronic, T‐cell–mediated disease frequently accompanied by xerostomia. Prior work suggests reduced salivary M3 muscarinic acetylcholine receptor (M3R) may contribute to hyposalivation.
Farzaneh Agha‐hosseini, Mahsa Koochaki, Mahdieh‐Sadat Moosavi, Iraj Mirzaei‐Dizgah, Mina Khayamzadeh   +4 more
doaj   +2 more sources

Inhibition of m3 muscarinic acetylcholine receptors by local anaesthetics [PDF]

British Journal of Pharmacology, 2001
1. Muscarinic m1 receptors are inhibited by local anaesthetics (LA) at nM concentrations. To elucidate in more detail the site(s) of LA interaction, we compared these findings with LA effects on m3 muscarinic receptors. 2.
Manuela De Klaver, Marcel E Durieux, Hollmann, M. W., Carsten H Ritter, de Klaver, M., Durieux, M. E., Ritter, C. H., Kamatchi, G. L., Henle, P., Philipp Henle, Markus W Hollmann, Ganesan L Kamatchi   +11 more
core   +4 more sources

Teaching an Old Drug New Tricks: Agonism, Antagonism, and Biased Signaling of Pilocarpine through M3 Muscarinic Acetylcholine Receptor [PDF]

Mol Pharmacol, 2017
Alexey Pronin, Qiang Wang, Vladlen Z. Slepak   +2 more
openalex   +2 more sources

Chronic exposure to the anti-M3 muscarinic acetylcholine receptor autoantibody in pemphigus vulgaris contributes to disease pathophysiology [PDF]

J Biol Chem, 2022
Alex I. Chernyavsky, Mykhailo M. Khylynskyi, Krupa G. Patel, Sergei A. Grando   +3 more
openalex   +2 more sources

Synergistic mechanisms of medullary cholinergic-serotonergic pathway interactions in regulating neuronal excitability and locomotor activities [PDF]

Communications Biology
Medullary serotonergic (5-HT) neurons play a pivotal role in locomotor initiation. While these neurons receive cholinergic innervation, the functional consequences and underlying mechanisms remain poorly understood. Using ePet-EYFP transgenic mice (P3–P6)
Yi Cheng, Yue Dai, Renkai Ge, Qiang Zhang   +3 more
doaj   +2 more sources

The molecular basis of oligomeric organization of the human m3 muscarinic acetylcholine receptor [PDF]

Molecular Pharmacology, 2015
G protein–coupled receptors, including the M3 muscarinic acetylcholine receptor, can form homo-oligomers. However, the basis of these interactions and the overall organizational structure of such oligomers are poorly understood.
Alvarez-Curto, Elisa, Marsango, Sara, Liste, Maria J., Ward, Richard J., Milligan, Graeme, Caltabiano, Gianluigi   +5 more
core   +3 more sources

Random Mutagenesis of the M3 Muscarinic Acetylcholine Receptor Expressed in Yeast [PDF]

Journal of Biological Chemistry, 2003
Clarice Schmidt, Bo Li, Lanh M. Bloodworth, Isolde Erlenbach, Fu‐Yue Zeng, Jürgen Wess   +5 more
openalex   +2 more sources

Muscarinic Acetylcholine Receptor M3

, 2020
National Cancer Institute
openalex   +2 more sources

Reduced M3 muscarinic acetylcholine receptor expression in gestational diabetes mellitus: implications for placental dysfunction and vascular regulation

The Journal of Maternal-Fetal & Neonatal Medicine
Objectives Gestational diabetes mellitus (GDM) is a prevalent metabolic disorder affecting pregnancy, leading to significant maternal and fetal complications.
Süleyman Cemil Oğlak, Fırat Aşir, Tuğcan Korak, Ayşegül Aşır, Emine Zeynep Yılmaz, Elif Ağaçayak   +5 more
openalex   +3 more sources

Muscarinic Stimulation of Pancreatic Insulin and Glucagon Release Is Abolished in M3 Muscarinic Acetylcholine Receptor–Deficient Mice [PDF]

Diabetes, 2004
Pancreatic muscarinic acetylcholine receptors play an important role in stimulating insulin and glucagon secretion from islet cells. To study the potential role of the M3 muscarinic receptor subtype in cholinergic stimulation of insulin release, we initially examined the effect of the muscarinic agonist, oxotremorine-M (Oxo-M), on insulin secretion ...
Alokesh Duttaroy, Charles L. Zimliki, Dinesh Gautam, Yinghong Cui, David Mears, Jürgen Wess   +5 more
openalex   +3 more sources