Biomolecules, 2021 Background: Underage drinking is associated with health risk behaviors. Serum keratin-18 (CK18) levels are increased in liver diseases and may be biomarkers of outcome. The purpose of this study was to determine if the total CK18 (M65) or caspase-cleaved
Katarzyna Zdanowicz +2 more
exaly +3 more sources
Expression of M30 and M65 in celiac disease. Analytical cross-sectional study [PDF]
São Paulo Medical Journal, 2018 BACKGROUND: The role of villous atrophy in apoptosis, a distinctive feature of celiac disease, is a matter of controversy. The aim of this study was to determine the apoptosis rate through immunohistochemical staining for M30 and M65 in celiac disease ...
Evrim Kahramanoğlu Aksoy +6 more
doaj +4 more sources
Serum Level of Cytokeratin 18 (M65) as a Prognostic Marker of High Cardiovascular Disease Risk in Individuals with Non-Alcoholic Fatty Liver Disease [PDF]
Biomolecules, 2023 Alterations in apoptosis, as reflected by circulating Cytokeratin 18 (CK18), are involved in the progression of non-alcoholic fatty liver disease (NAFLD) to non-alcoholic steatohepatitis and atherogenesis. We aimed to explore the discriminant accuracy of
Sabrina Pagano +4 more
doaj +2 more sources
Cytokeratin 18 as a Novel Biomarker in Patients with Hypertrophic Cardiomyopathy [PDF]
CellsHypertrophic cardiomyopathy (HCM) is a heart muscle disease associated with an increased risk for sudden cardiac death (SCD). Cytokeratin 18-based proteins, such as M30 and M65 antigens, are known cell-death biomarkers. M30 antigen is released from cells
Konstantinos Fragkiadakis +22 more
doaj +2 more sources
A New Lactone from Strain M65 that Inhibits the Motility of Zoospores [PDF]
Natural Product Communications, 2016 In a search for endophytes from medicinal plants of Bangladesh, we isolated the M65 fungal strain from the fruit of Azadirachta indica . Following chemical screening, chromatographic purification of the culture extract of strain M65 led to the isolation ...
Muhammad Abdul Mojid Mondol +4 more
doaj +4 more sources
Clinical significance of serum M30 and M65 levels in patients with breast cancer
Biomedicine and Pharmacotherapy, 2014 M30 and M65 are relatively new assays that detect different circulating forms of the epithelial cell structural protein cytokeratin18. The objective of this study was to determine the clinical significance of the serum levels of M30 and M65 in patients with breast cancer. A total of 80 patients with a pathologically confirmed diagnosis of breast cancer
Faruk Tas +2 more
exaly +3 more sources
Modeling Reductions in Liver Fat: Comparing Noninvasive Tests to Magnetic Resonance Imaging–Proton Density Fat Fraction [PDF]
Gastro Hep AdvancesBackground and Aims: Magnetic resonance imaging–proton density fat fraction (MRI-PDFF) is an accurate, noninvasive tool for diagnosing metabolic dysfunction–associated steatotic liver disease, but its feasibility is limited in routine clinical practice ...
Santos Carvajal-Gonzalez +6 more
doaj +2 more sources
Serum Levels of Candida albicans 65-kDa Mannoprotein (CaMp65p) Correlate with Liver Disease in Patients with Alcohol Use Disorder [PDF]
MicroorganismsAlcohol-associated liver disease is a global health burden with high morbidity and mortality, and the fungal microbiome is important for its progression. In particular, Candida albicans and C.
Julia T. Schnabl +3 more
doaj +2 more sources
Preliminary study on the diagnostic value of LEAP-2 and CK18 in biopsy-proven MAFLD [PDF]
BMC GastroenterologyMetabolic Dysfunction-Associated Fatty Liver Disease (MAFLD) has become the leading cause of chronic liver disease. Liver biopsy, as the diagnostic gold standard, is invasive and has sampling bias, making it particularly important to search for sensitive
Zhi Liu +5 more
doaj +2 more sources
Diagnostic value of serum M30 and M65 in patients with nasopharyngeal carcinoma
Tumor Biology, 2014 M30 and M65 are circulating fragments of cytokeratin 18 released during apoptotic cell death and regarded as markers of cell death in patients with various tumor types. Our aim was to investigate the clinical and prognostic significance of the serum M30 and M65 concentrations in patients with advanced nasopharyngeal carcinoma.
Makbule Tambaş +2 more
exaly +3 more sources