Results 21 to 30 of about 2,347 (191)

Prognostic biomarkers in lung cancer patients in terms of long-term survival

open access: yesTurkish Journal of Internal Medicine, 2021
Introduction: We aimed to investigate the predictive effect of serum M30 and M65 antigens on long-term prognosis in patients with advanced stage lung cancer before and after the first dose of chemotherapy.
Belkis Nihan Coskun   +4 more
doaj   +1 more source

Serum Cytokeratin 18 as a Metastatic and Therapeutic Marker for Extramammary Paget’s Disease

open access: yesActa Dermato-Venereologica, 2022
Extramammary Paget’s disease (EMPD) is a rare cutaneous adenocarcinoma with unfavourable prognosis once it becomes invasive. A tumour marker that reflects disease progression is required for adequate management of EMPD. Cytokeratin 18 is highly expressed
Mariko Urano-Takaoka   +7 more
doaj   +1 more source

Non-invasive Biomarkers of Liver Inflammation and Cell Death in Response to Alcohol Detoxification

open access: yesFrontiers in Physiology, 2021
IntroductionAlcohol-related liver disease (ALD) represents the most common liver disease worldwide, however, the underlying molecular mechanisms are still poorly understood.
Manuela G. Neuman   +3 more
doaj   +1 more source

Oxidative stress, DNA damage and apoptosis levels in those who use borderline high level fluoride content drinking water

open access: yesJournal of Contemporary Medicine, 2020
Aim: Fluoride is necessary for tooth and bone development, but when exposed to excessive levels can cause oxidative stress, DNA damage, apoptosis, fluorosis and cancer.
Adnan Kirmit   +4 more
doaj   +1 more source

Serum keratin‐18 detects hepatic inflammation and predicts progression in compensated alcohol‐associated liver disease

open access: yesHepatology Communications, 2022
Alcohol‐associated liver fibrosis accumulates over decades, driven by hepatic inflammation and cell death. We investigated the diagnostic accuracy of keratin‐18 degradation, measured using serum M30 and M65 levels, and the ActiTest for hepatic ...
Katrine Holtz Thorhauge   +9 more
doaj   +1 more source

PACAP-PAC1 receptor inhibition is effective in opioid induced hyperalgesia and medication overuse headache models

open access: yesiScience, 2023
Summary: Opioids prescribed for pain and migraine can produce opioid-induced hyperalgesia (OIH) or medication overuse headache (MOH). We previously demonstrated that pituitary adenylate cyclase activating polypeptide (PACAP) is upregulated in OIH and ...
Zachariah Bertels   +5 more
doaj   +1 more source

The Roles of Carbon-Nitrogen Synergy and Phosphate Regulation in Producing Higher Yield of Vancomycin by Amycolatopsis orientalis. [PDF]

open access: yesMicrobiologyopen
Systematic media optimization in Amycolatopsis orientalis identified maltodextrin, soy‐based nitrogen sources, and phosphate regulation as key drivers of vancomycin yield. Knockout and feeding trials demonstrated essential nutrient roles, offering a cost‐effective, scalable strategy for enhanced antibiotic production.
Mani V, Jeyachandran S, Aman M.
europepmc   +2 more sources

Serum cell death biomarkers for prediction of liver fibrosis and poor prognosis in primary biliary cirrhosis. [PDF]

open access: yesPLoS ONE, 2015
The development of simple, noninvasive markers of liver fibrosis is urgently needed for primary biliary cirrhosis (PBC). This study examined the ability of several serum biomarkers of cell death to estimate fibrosis and prognosis in PBC.
Tomohiro Sekiguchi   +10 more
doaj   +1 more source

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