Results 281 to 290 of about 58,783 (322)

METTL3 promotes pancreatic cancer immune escape by m6A modification of lncRNA AFAP1-AS1 to enhance EGR2 stability. [PDF]

Eur J Med Res
Zhu D, Shen R, Li M.
europepmc   +1 more source

The molecular mechanism of IGF2BP3 promoting the malignant progression of lung cancer. [PDF]

Cancer Cell Int
Wu C, Ma Y, Li J, Hai B, Zhou Y, Cao F, Kang X, Xu X.   +7 more
europepmc   +1 more source

m6A-Modified Nucleotide Bases Improve Translation of In Vitro-Transcribed Chimeric Antigen Receptor (CAR) mRNA in T Cells. [PDF]

Int J Mol Sci
Lao N, Li S, Ainciburu M, Barron N.
europepmc   +1 more source

m6A RNA methylation modulates antiviral response in celiac disease. [PDF]

Genes Immun
Sebastian-delaCruz M, Olazagoitia-Garmendia A, Pascual-Gonzalez I, Mendoza LM, Legarda M, Tutau C, Bujanda L, Ghosh S, Santin I, Postler TS, Bilbao JR, Castellanos-Rubio A.   +11 more
europepmc   +1 more source

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Topology of the human and mouse m6A RNA methylomes revealed by m6A-seq

Nature, 2012
An extensive repertoire of modifications is known to underlie the versatile coding, structural and catalytic functions of RNA, but it remains largely uncharted territory. Although biochemical studies indicate that N(6)-methyladenosine (m(6)A) is the most prevalent internal modification in messenger RNA, an in-depth study of its distribution and ...
D. Dominissini, S. Moshitch-Moshkovitz, Schraga Schwartz, M. Salmon-Divon, L. Ungar, Sivan Osenberg, K. Cesarkas, J. Jacob-Hirsch, N. Amariglio, M. Kupiec, R. Sorek, G. Rechavi   +11 more
semanticscholar   +3 more sources

The epitranscriptome beyond m6A

Nature Reviews Genetics, 2020
Following its transcription, RNA can be modified by >170 chemically distinct types of modifications - the epitranscriptome. In recent years, there have been substantial efforts to uncover and characterize the modifications present on mRNA, motivated by the potential of such modifications to regulate mRNA fate and by discoveries and advances in our ...
David Wiener, Schraga Schwartz
semanticscholar   +3 more sources

Mapping single-nucleotide m6A by m6A-REF-seq

Methods, 2022
The past few years have witnessed rapid progress in the field of RNA modifications. As the most prevailing modification on eukaryotic mRNA, m6A is characterized to play a vital role in various cellular activities. However, limitations of the detection method impede functional studies of m6A. Here we introduce m6A-REF-seq, a powerful and straightforward
Hong-Xuan, Chen, Zhang, Zhang, Dong-Zhao, Ma, Li-Qian, Chen, Guan-Zheng, Luo   +4 more
openaire   +2 more sources