Results 151 to 160 of about 24,574 (283)
The Kaohsiung Journal of Medical Sciences, EarlyView.ABSTRACT Triple‐negative breast cancer (TNBC) is characterized as an aggressive malignancy with limited therapeutic options. The circular RNA circ_0006174 has been implicated in oncogenic processes across various cancers; however, its specific role in the pathogenesis of TNBC remains unclear.
Yong‐Zhe Tang +4 more
wiley +1 more source
PLoS Genetics, 2019 N6-Methyladenosine (m6A) RNA methylation plays important roles during development in different species. However, knowledge of m6A RNA methylation in monocots remains limited.
Fan Zhang +10 more
doaj +1 more source
A reference genome and methylome for the Plasmodium knowlesi A1-H.1 line. [PDF]
, 2017 Plasmodium knowlesi, a common parasite of macaques, is recognised as a significant cause of human malaria in Malaysia. The P. knowlesi A1H1 line has been adapted to continuous culture in human erythrocytes, successfully providing an in vitro model to ...
Benavente, Ernest Diez +12 more
core +1 more source
Ultraviolet-Induced DNA Damage Promotes RNA m6A Methylation [PDF]
Cancer Discovery, 2017 Abstract m6A RNA methylation rapidly recruits Pol κ to UV-induced damage sites to facilitate DNA repair.
openaire +1 more source
The Kaohsiung Journal of Medical Sciences, EarlyView.ABSTRACT Ibrutinib resistance remains a major obstacle in the treatment of diffuse large B‐cell lymphoma (DLBCL). Fat mass and obesity‐associated protein (FTO) has been implicated in drug resistance through its regulation of N6‐methyladenosine (m6A) modifications; however, whether FTO mediates ibrutinib resistance in DLBCL remains unclear.
Ting‐Ting Lu +5 more
wiley +1 more source
M6A RNA methylation-mediated RMRP stability renders proliferation and progression of non-small cell lung cancer through regulating TGFBR1/SMAD2/SMAD3 pathway [PDF]
, 2021 Hang Yin +9 more
openalex +1 more source
SNP- and haplotype-based genome-wide association studies for growth, carcass, and meat quality traits in a Duroc multigenerational population [PDF]
, 2016 Average linkage disequilibrium coefficient (r2) values plotted against intermarker distance for all autosomal chromosomes.
Hironori Sakuma +10 more
core +6 more sources
m6A RNA methylation attenuates thermotolerance in Arabidopsis
AbstractHeat stress severely affects plant growth, causing significant crop yield losses. To counteract this, plants employ adaptive strategies, including chromatin and transcriptional regulation of heat stress-related genes. However, the role of RNA methylation in heat stress response remains unclear.
Kirti Shekhawat +6 more
openaire +2 more sources
m6A RNA methylation, a new hallmark in virus-host interactions
Journal of General Virology, 2017 The role of m6A methylation of RNA has remained elusive for decades, but recent technological advances are now allowing the mapping of the m6A methylation landscape at nucleotide level. This has spurred an explosion in our understanding of the role played by RNA epigenetics in RNA biology.
Brocard, Michele +2 more
openaire +4 more sources
The Kaohsiung Journal of Medical Sciences, EarlyView.ABSTRACT Radiotherapy effectively eradicates tumor cells but can also trigger pyroptotic damage in vascular endothelial cells. This study investigates the role of interferon regulatory factor 1 (IRF1) in radiation‐induced endothelial injury, aiming to provide mechanistic insights for optimizing radiotherapy.
Chen Li +4 more
wiley +1 more source