Results 141 to 150 of about 937,277 (225)

The Role of m6A-Mediated DNA Damage Repair in Tumor Development and Chemoradiotherapy Resistance

Cancer Control
Among the post-transcriptional modifications, m6A RNA methylation has gained significant research interest due to its critical role in regulating transcriptional expression.
Li Qu, Si jian Liu, Ling Zhang, Jia Feng Liu, Ying Jie Zhou, Peng Hui Zeng, Qian Cheng Jing, Wen Jun Yin   +7 more
doaj   +1 more source

M6A RNA methylation-mediated RMRP stability renders proliferation and progression of non-small cell lung cancer through regulating TGFBR1/SMAD2/SMAD3 pathway

Cell Death and Differentiation, 2021
Hang Yin, Lin Chen, Shi-Qi Piao, Yi-Ru A. Wang, Zhange Li, Yuan Lin, Xue-Qing Tang, Hui-Juan Zhang, Hai-Yang Zhang, Xiao-Yuan Wang   +9 more
semanticscholar   +1 more source

The role of m6A-RNA methylation in stress response regulation

, 2017
SummaryN6-Methyladenosine (m6A) is an abundant internal RNA modification that regulates transcript processing and translation. The regulation of brain m6A by stressful stimuli in vivo and its role in the stress response are currently unknown.Here, we ...
Janine Arloth, Matthias Eder, Peter Weber, Manfred Uhr, Carola Eggert, Lisa Tietze, Alon Chen, Carsten T. Wotjak, Mathias V. Schmidt, Monika Rex-Haffner, Simone Röh, Paul M. Kaplick, Mareen Engel, Jan M. Deussing, Elisabeth B. Binder, Mira Jakovcevski   +15 more
core   +1 more source

m6A RNA methylation in mammals [PDF]

Nature Structural & Molecular Biology, 2014
openaire   +1 more source

Drugs targeting synaptic RNA m6A methylation regulate synaptic transmission and plasticity in the rat hippocampus

m6A methylation is the most abundant modification in eukaryotic mRNA and has been implicated in epitranscriptomic regulation of various cellular functions.
Teino, Indrek, Rhee, Jun Kyu, Renzi, Brunaldo, Lauri, Sari E., Keskinen, Rahaf, Saarma, Mart   +5 more
core   +1 more source

Comprehensive analysis of m6A RNA methylation regulators in esophageal carcinoma

Translational Cancer Research
N6-methyladenosine (m6A) is the most pervasive modification of RNA methylation in eukaryotic cells. m6A modification plays a pivotal role in tumorigenesis and progression in many types of cancers. Until now, the role of m6A modification in esophageal carcinoma (ESCA) has remained obscure.
Yang, Hongzhao, Liu, Jianbo, Li, Li, Wang, Xiaodong, Li, Zhigui   +4 more
openaire   +2 more sources

The Role of m6A RNA methylation in chikungunya virus Replication [PDF]

Chikungunya virus (CHIKV) is an emerging human pathogen transmitted through the mosquitoes Aedes aegypti and Aedes albopictus. CHIKV has a widening distribution due to the impact of globalization, including changing land use and international travel and ...
DeJesus, Veronica Anne
core   +2 more sources

m6A RNA Methylation in Plants: From Molecular Insights to Applications

Annual Review of Plant Biology
Epitranscriptomics, the study of dynamic and site-specific RNA modifications, has emerged as a crucial layer of gene regulation in plants, paralleling the role of classical epigenetic mechanisms such as DNA and histone modifications. Among these, N 6 -methyladenosine (m
Peizhe, Song, Zhihe, Cai, Guifang, Jia
openaire   +2 more sources

m6A RNA methylation in mammalian oocytes and preimplantation embryos: implications for developmental competence. [PDF]

Front Vet Sci
Cosseddu C, Succu S, Mossa F, Frau A, Palmerini MG, Ledda S, Bebbere D.   +6 more
europepmc   +1 more source

Rewriting the brain: m6A RNA methylation as an emerging epitranscriptomic regulator in major depressive disorder. [PDF]

Front Mol Neurosci
Verma AK, Mori H, Roy B, Dwivedi Y.
europepmc   +1 more source