Results 121 to 130 of about 937,277 (225)
m6A RNA methylation drives kidney fibrosis by upregulating β-catenin signaling
International Journal on Biological SciencesN6-methyladenosine (m6A) methylation plays a crucial role in various biological processes and the pathogenesis of human diseases. However, its role and mechanism in kidney fibrosis remain elusive.
Yinyi Long +9 more
semanticscholar +1 more source
, 2021 N6-methyladenosine (m6A) RNA methylation has emerged as an important factor in various biological processes by regulating gene expression. However, the dynamic profile, function and underlying molecular mechanism of m6A modification during skeletal ...
Shuang Tao (11510260) +12 more
core +1 more source
Cell ReportsSummary: m6A RNA methylation is the most prevalent internal modification in mammalian mRNAs and is involved in many biological processes. METTL16 is a recently identified RNA m6A methyltransferase.
Haixia Li +7 more
doaj +1 more source
Unraveling the landscape of m6A RNA methylation in wound healing and scars. [PDF]
Cell Death DiscovAbstractWound healing is a complex process involving sequential stages of hemostasis, inflammation, proliferation, and remodeling. Multiple cell types and factors, including underlying conditions like diabetes and bacterial colonization, can influence healing outcomes and scar formation.
Zhang Q, Dong L, Gong S, Wang T.
europepmc +4 more sources
, 2021 N6-methyladenosine (m6A) RNA methylation has emerged as an important factor in various biological processes by regulating gene expression. However, the dynamic profile, function and underlying molecular mechanism of m6A modification during skeletal ...
Shuang Tao (11510260) +12 more
core +1 more source
mSystemsHydrogen peroxide (H2O2) is a typical representative substance of environmental oxidative stress. Exogenous substances can alter epigenetic modifications from the DNA to the RNA level through oxidative stress.
Chenyu Zhu +10 more
doaj +1 more source
The critical role of m6A methylation in the pathogenesis of Graves' ophthalmopathy
Eye and Vision, 2020 Purpose To investigate the role of N6-methyladenosine (m6A) RNA modification in the pathogenesis of Graves' ophthalmopathy (GO). Methods Surgically excised extraocular muscles from 7 patients with GO and 5 subjects without GO were used.
Li Zhu +14 more
doaj +1 more source
Circadian Clock Regulation of Hepatic Lipid Metabolism by Modulation of m6A mRNA Methylation
Cell Reports, 2018 Summary: Transcriptional regulation of circadian rhythms is essential for lipid metabolic homeostasis, disruptions of which can lead to metabolic diseases. Whether N6-methyladenosine (m6A) mRNA methylation impacts circadian regulation of lipid metabolism
Xiang Zhong +17 more
doaj +1 more source
High-throughput m6A-seq reveals RNA m6A methylation patterns in the chloroplast and mitochondria transcriptomes of Arabidopsis thaliana. [PDF]
, 2017 This study is the first to comprehensively characterize m6A patterns in the Arabidopsis chloroplast and mitochondria transcriptomes based on our open accessible data deposited in NCBI's Gene Expression Omnibus with GEO Series accession number of GSE72706.
Zegang Wang +6 more
core +1 more source
Identifying cortical specific long noncoding RNAs modified by m6A RNA methylation in mouse brains
, 2021 Proper development of the mammalian cerebral cortex relies on precise gene expression regulation. Increasing evidence shows that cortical development is regulated by both mRNAs and long noncoding RNAs (lncRNAs), which also are modified by N6 ...
Zhen Zhang +6 more
core +1 more source