Results 111 to 120 of about 937,277 (225)
The roles of RNA N6-methyladenosine in esophageal cancer
Heliyon, 2022 Esophageal cancer is a malignant tumour with a high degree of malignancy and high mortality. Its pathogenesis and treatment strategy remain unclear.
Chuan Teng +6 more
doaj +1 more source
Cancer Communications, 2023 Diversified histone deacetylation inhibitors (HDACis) have demonstrated encouraging outcomes in multiple malignancies. N6‐methyladenine (m6A) is the most prevalent messenger RNA modification that plays an essential role in the regulation of tumorigenesis.
Ai Zhuang +7 more
semanticscholar +1 more source
Unique and Specific m6A RNA Methylation in Mouse Embryonic and Postnatal Cerebral Cortices
, 2020 N6-methyladenosine (m6A)-mediated epitranscriptomic regulation is critical for various physiological processes. Genetic studies demonstrate that proper m6A-methylation is required for mouse brain development and function.
Tao Sun +5 more
core +1 more source
, 2021 N6-methyladenosine (m6A) RNA methylation has emerged as an important factor in various biological processes by regulating gene expression. However, the dynamic profile, function and underlying molecular mechanism of m6A modification during skeletal ...
Shuang Tao (11510260) +12 more
core +1 more source
Frontiers in Cardiovascular Medicine, 2021 Aim: To systematically classify the profile of the RNA m6A modification landscape of neonatal heart regeneration.Materials and Methods: Cardiomyocyte proliferation markers were detected via immunostaining.
Chuanxi Yang +7 more
doaj +1 more source
, 2021 N6-methyladenosine (m6A) RNA methylation has emerged as an important factor in various biological processes by regulating gene expression. However, the dynamic profile, function and underlying molecular mechanism of m6A modification during skeletal ...
Shuang Tao (11510260) +12 more
core +1 more source
Molecular Cancer, 2019 Analogous to DNA methylation and histone modification, RNA modification, as another epigenetic layer, plays an important role in many diseases, especially in tumours.
Bin-bin Hu +6 more
doaj +1 more source
, 2021 N6-methyladenosine (m6A) RNA methylation has emerged as an important factor in various biological processes by regulating gene expression. However, the dynamic profile, function and underlying molecular mechanism of m6A modification during skeletal ...
Shuang Tao (11510260) +12 more
core +1 more source
RBM15 in diseases: Molecular mechanisms and clinical opportunities from RNA m6A methylation
Genes and DiseasesRNA m6A methylation is the most common type of RNA modification, and RBM15 regulates various cellular processes by writing m6A methylation on RNA. m6A methylation mediated by RBM15 significantly affects RNA stability and translational efficiency, thereby
Fengze Li +6 more
doaj +1 more source
Current Insights into m6A RNA Methylation and Its Emerging Role in Plant Circadian Clock
, 2023 N6-adenosine methylation (m6A) is a prevalent form of RNA modification found in the expressed transcripts of many eukaryotic organisms. Moreover, m6A methylation is a dynamic and reversible process that requires the functioning of various proteins and ...
Lanshuo Wang +4 more
core +1 more source