Results 131 to 140 of about 937,277 (225)

DRUM: Inference of Disease-Associated m6A RNA Methylation Sites From a Multi-Layer Heterogeneous Network [PDF]

, 2019
Recent studies have revealed that the RNA N6-methyladenosine (m6A) modification plays a critical role in a variety of biological processes and associated with multiple diseases including cancers.
Song-Yao Zhang, Yujiao Tang, Xiangyu Wu, Bowen Song, Shao-Wu Zhang, Zhen Wei, Jia Meng, Kunqi Chen, Yufei Huang   +8 more
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Table_1_Dynamic m6A mRNA Methylation Reveals the Role of METTL3/14-m6A-MNK2-ERK Signaling Axis in Skeletal Muscle Differentiation and Regeneration.XLSX

, 2021
N6-methyladenosine (m6A) RNA methylation has emerged as an important factor in various biological processes by regulating gene expression. However, the dynamic profile, function and underlying molecular mechanism of m6A modification during skeletal ...
Shuang Tao (11510260), Yan-Xia Hu (11510263), Zhen-Dong Xiao (11510269), Yu-Jia Sun (480815), Jie-Hua He (11510257), Ya-Rui Hou (11510266), Yan-Wen Peng (9665790), Hang Lei (668450), Jian-You Liao (248971), Li-Ting Diao (4282033), Bing Yang (142278), Qi Zhang (28502), Shu-Juan Xie (191702)   +12 more
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The relationship between the network of non-coding RNAs-molecular targets and N6-methyladenosine modification in tumors of urinary system

Cell Death and Disease
N6-methyladenosine (m6A) methylation, a prevalent eukaryotic post-transcriptional modification, is involved in multiple biological functions, including mediating variable splicing, RNA maturation, transcription, and nuclear export, and also is vital for ...
Ruiming Li, Chunming Zhu, Yuan Wang, Xia Wang, Yibing Wang, Jiahe Wang, Kefeng Wang   +6 more
doaj   +1 more source

Analysis of m6A RNA methylation in Caenorhabditis elegans [PDF]

Cell Discovery, 2020
Erdem Sendinc, David Valle-Garcia, Alan Jiao, Yang Shi   +3 more
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Transcriptome-Wide High-Throughput m6A Sequencing of Differential m6A Methylation Patterns in the Human Rheumatoid Arthritis Fibroblast-Like Synoviocytes Cell Line MH7A

Journal of Inflammation Research, 2021
Hui Jiang1,2 *,* Kefeng Cao3 *,* Chang Fan,1,2 Xiaoya Cui,1,2 Yanzhen Ma,1,2 Jian Liu1 1Experimental Center of Clinical Research, First Affiliated Hospital of Anhui University of Chinese Medicine, Hefei, Anhui, People’s Republic of China; 2School ...
Jiang H, Cao K, Fan C, Cui X, Ma Y, Liu J   +5 more
doaj  

Analyzing the relationship of RNA and DNA methylation with gene expression

Genome Biology
Background DNA 5-methylcytosine (5mC) and RNA N6-methyladenosine (m6A) methylation are prevalent modifications in eukaryotes, both playing crucial roles in gene regulation. Recent studies have explored their crosstalk and impact on transcription. However,
Shangqian Xie, Darren Hagen, Gabrielle M. Becker, Kimberly M. Davenport, Katie A. Shira, Morgan R. Stegemiller, Jacob W. Thorne, Sarem Khilji, Denise Konetchy, Patricia Villamediana, Brenda M. Murdoch, Stephanie D. McKay   +11 more
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Role Of M6A Rna Methylation In Skeletal Muscle Regeneration [PDF]

Skeletal muscle is essential in orchestrating voluntary movement and contributes to approximately half of the body\u27s overall mass. Dysregulation in proper skeletal muscle development can lead to muscle degenerative disorders, such as severe Duchenne ...
Onifade, Isreal Ayobami
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The subunit of RNA N6-methyladenosine methyltransferase OsFIP regulates early degeneration of microspores in rice.

PLoS Genetics, 2019
N6-Methyladenosine (m6A) RNA methylation plays important roles during development in different species. However, knowledge of m6A RNA methylation in monocots remains limited.
Fan Zhang, Yu-Chan Zhang, Jian-You Liao, Yang Yu, Yan-Fei Zhou, Yan-Zhao Feng, Yu-Wei Yang, Meng-Qi Lei, Mei Bai, Hong Wu, Yue-Qin Chen   +10 more
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The role of m6A RNA methylation in infectious diseases

Frontiers in RNA Research
Among over 170 known RNA modifications, N6-methyladenosine (m6A) stands out as the most ubiquitous and extensively studied modification, found in different cellular RNA. The m6A plays a pivotal role in regulating RNA nuclear export, stability, secondary structure, translation, and degradation eventually determining the gene expression.
Nidhi Yadav, Reshma Khan, Sandeep Goyal, Rajesh Kumari   +3 more
openaire   +2 more sources

RNA m6A methylation participates in regulation of postnatal development of the mouse cerebellum

, 2018
Background N6-methyladenosine (m6A) is an important epitranscriptomic mark with high abundance in the brain. Recently, it has been found to be involved in the regulation of memory formation and mammalian cortical neurogenesis.
Chunhui Ma, Yao Zhang, Li, Qing, Gaolang Wu, Liu, Chunying, Zhang, Zhi-Wei, Wang, Di, Zhi-Wei Zhang, Lv, Hongyi, Teng, Xufei, Shunli Zhao, Wu, Gaolang, Zhao, Shunli, Klungland, Arne, Mengqi Chang, Ma, Chunhui, Chunying Liu, Weilong Zhang, Xufei Teng, Yamei Niu, Zhang, Yao, Xue He, Wei-Min Tong, Arne Klungland, He, Xue, Song, Shuhui, Chang, Mengqi, Niu, Yamei, Tong, Wei-Min, Qing Li, Hongyi Lv, Shuhui Song, Zhang, Weilong, Di Wang   +33 more
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