Results 91 to 100 of about 36,088 (121)

Cell cycle proteins: Linking the cell cycle to tumors. [PDF]

open access: yesOncol Res
Zhong J   +11 more
europepmc   +1 more source

Genome-wide screen reveals dependence of break induced replication on several distinct checkpoints. [PDF]

open access: yesNat Commun
Liu L   +8 more
europepmc   +1 more source

KRAS-induced STN1 (OBFC1) promotes proper CTC1-STN1-TEN1 complex-independent DNA double-strand break repair and cell cycle checkpoint maintenance in pancreatic cancer. [PDF]

open access: yesNucleic Acids Res
Shen C   +15 more
europepmc   +1 more source
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Checkpoint kinase 1‐mediated phosphorylation of Cdc25C and bad proteins are involved in antitumor effects of loratadine‐induced G2/M phase cell‐cycle arrest and apoptosis

Molecular Carcinogenesis, 2006
AbstractIn this study, we first demonstrated that loratadine (LOR), a promising world widely used oral anti‐histamine, effectively inhibits growth of tumors derived from human colon cancer cells (COLO 205) in an in vivo setting. In vitro study demonstrated that the anti‐tumor effects of LOR in COLO 205 cells were mediated by causing G2/M phase cell ...
Jinn-Shiun, Chen   +7 more
openaire   +2 more sources

Triazoloacridone C-1305 abrogates the restriction checkpoint in cells lacking functional p53 and promotes their accumulation in the G2/M phase of the cell cycle.

Journal of experimental therapeutics & oncology, 2011
Triazoloacridone C-1305, a new topoisomerase II inhibitor, exhibits potent cytostatic activity toward various tumours under in vitro and in vivo conditions. Interestingly, mouse cells lacking poly(ADP-ribose) polymerase-1 are much more sensitive to C-1305 than their normal counterparts.
Margarita, Maurer   +3 more
openaire   +1 more source

214 PI3K CLASS 1B CONTROLS THE CELL CYCLE CHECKPOINT AT THE G2/M PHASE PROMOTING CELL PROLIFERATION IN HEPATOCELLULAR CARCINOMA

Journal of Hepatology, 2011
F. Dituri   +6 more
openaire   +1 more source

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