Results 131 to 140 of about 5,202 (155)

Chromatin factor YY1 controls fetal hematopoietic stem cell migration and engraftment in mice. [PDF]

J Clin Invest
Saka S, Lu Z, Wang Y, Liu P, Singh DK, Lee JP, Palii CG, Alvarez TR, Assumpção AL, You X, Zhang J, Brand M, Atchison ML, Pan X.   +13 more
europepmc   +1 more source

Pathogenicity and virulence of the blast fungus <i>Magnaporthe oryzae</i>. [PDF]

Virulence
Molinari C, Talbot NJ.
europepmc   +1 more source

Monocyte-Derived Macrophages-Synovial Fibroblasts Crosstalk Unravels Oncostatin Signaling Network as a Driver of Synovitis in Osteoarthritis. [PDF]

Arthritis Rheumatol
Laouteouet D, Bortolotti O, Marineche L, Hannemann N, Chambon M, Glasson Y, Dumé AS, De Lima J, Fournial M, Touchet D, Séverac D, Leccia F, Duperray C, Michaud HA, Djouad F, Le Goff B, Blanchard F, Apparailly F, Courties G.   +18 more
europepmc   +1 more source

Peroxisomal core structures segregate diverse metabolic pathways. [PDF]

Nat Commun
Bäcker N, Ast J, Martorana D, Renicke C, Berger J, Mais CN, Christ M, Stehlik T, Heimerl T, Wernet V, Taxis C, Pané-Farré J, Bölker M, Klatt JM, Sandrock B, Schink KO, Bange G, Freitag J.   +17 more
europepmc   +1 more source

Reviewer #2 (Public review): The Mac1 ADP-ribosylhydrolase is a Therapeutic Target for SARS-CoV-2

openaire   +2 more sources

Reviewer #3 (Public review): The Mac1 ADP-ribosylhydrolase is a therapeutic target for SARS-CoV-2

openaire   +2 more sources

Mac1 Positive Cells Are Required for Enhancement of Splenocytes Proliferation Caused by Bisphenol A

Bioscience, Biotechnology and Biochemistry, 2004
We examined the effects of bisphenol A (BPA) on immune cells and it was shown that BPA upregulated the proliferation of murine splenocytes stimulated with Concanavalin A (ConA). The upregulating effects of BPA were removed with depleting Mac1+ cells from the splenocytes. This study provides evidence for the first time that Mac1+ cells were required for
Mitsuru Yoshida, Masao Gotō, Ono Hiroshi   +2 more
exaly   +3 more sources

Identification of a copper-induced intramolecular interaction in the transcription factor Mac1 from Saccharomyces cerevisiae [PDF]

EMBO Journal, 1998
Mac1 mediates copper (Cu)-dependent expression of genes involved in high-affinity uptake of copper ions in Saccharomyces cerevisiae. Mac1 is a transcriptional activator in Cu-deficient cells, but is inhibited in Cu-replete cells. Mac1 resides within the nucleus in both Cu-deficient and Cu-loaded cells.
Dennis Winge, Laran Jensen
exaly   +3 more sources

SARS-CoV-2 Mac1 is required for IFN antagonism and efficient virus replication in cell culture and in mice

Proceedings of the National Academy of Sciences of the United States of America, 2023
Several coronavirus (CoV) encoded proteins are being evaluated as targets for antiviral therapies for COVID-19. Included in these drug targets is the conserved macrodomain, or Mac1, an ADP-ribosylhydrolase and ADP-ribose binding protein encoded as a small domain at the N terminus of nonstructural protein 3.
Catherine M Kerr, Robert Unckless
exaly   +6 more sources

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Structures of the Cuprous-Thiolate Clusters of the Mac1 and Ace1 Transcriptional Activators

Biochemistry, 2002
X-ray absorption spectroscopy on the minimal copper-regulatory domains of the two copper-regulated transcription factors (Ace1 and Mac1) in Saccharomyces cerevisiae revealed the presence of a remarkably similar polycopper cluster in both proteins. The Cu-regulatory switch motif of Mac1 consisting of the C-terminal first Cys-rich motif, designated the ...
Brown, K., Keller, G., Pickering, I., Harris, H., George, G., Winge, D.   +5 more
openaire   +3 more sources