Results 61 to 70 of about 2,769,211 (350)
Molecular Oncology, EarlyView.Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova +25 more
wiley +1 more source
Development of a wind turbine simulator
The Journal of Engineering, 2019 As a renewable energy source, wind power has become a hot research topic, despite the lack of wind-environment simulation equipment in most laboratories.
Yuan Sun, Ji Zhang, Yanru Zhou
doaj +1 more source
An experimental 100 kilowatt wind turbine generator [PDF]
, 1975 Experimental generator consists of two blades mounted on 100 foot tower, driving transmission train and electric generator mounted on top of tower. Machine generates 100 kW of electricity at wind speeds from 18 to 60 miles per hour. Yaw control mechanism
Johnson, W. R. +3 more
core +1 more source
Molecular Oncology, EarlyView.Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson +9 more
wiley +1 more source
Connections Between Adaptive Control and Optimization in Machine Learning
, 2019 This paper demonstrates many immediate connections between adaptive control and optimization methods commonly employed in machine learning. Starting from common output error formulations, similarities in update law modifications are examined. Concepts in
Annaswamy, Anuradha M. +4 more
core +1 more source
Molecular Oncology, EarlyView.Targeted therapy was evaluated in SHH medulloblastoma using neuroepithelial stem cell (NES) and tumor‐derived NES‐like (tNES) models in 2D monolayers and 3D spheroids. PI3K, AKT, and CDK4/6 inhibitors had minimal effects in NES but markedly reduced viability and growth and induced apoptosis in tNES cells, revealing distinct therapeutic vulnerabilities.
Monika Lukoseviciute +4 more
wiley +1 more source
Efficient Moving Object Segmentation in LiDAR Point Clouds Using Minimal Number of Sweeps
IEEE Open Journal of Signal ProcessingLiDAR point clouds are a rich source of information for autonomous vehicles and ADAS systems. However, they can be challenging to segment for moving objects as - among other things - finding correspondences between sparse point clouds of consecutive ...
Zoltan Rozsa +2 more
doaj +1 more source
Switched reluctance motor design for electric vehicles based on harmonics and back EMF analysis
The Journal of Engineering, 2019 Permanent magnet synchronous motors are widely accepted in automotive applications. The high torque density, high rotational speed with maximum efficiency in electric vehicle applications is technically challenging for motor design.
Abid Ali Shah Bukhari +7 more
doaj +1 more source
Supervisory controlled forest machines
FORESTRY BULLETIN, 2021 The article presents structural diagrams of an automated control system for technological processes and information flows of logging operations. The article includes subject and research methodology. The study in a field of logging operations confirms the fact of increasing rate of using special forest machinery like forest harvesters for conducting ...
A.V. Sirotov +4 more
openaire +1 more source
E2A selectively regulates TGF‐β–induced apoptosis in KRAS‐mutant non‐small cell lung cancer
Molecular Oncology, EarlyView.Ability to induce apoptosis by TGF‐β is frequently lost in advanced lung adenocarcinoma despite intact TGF‐β signaling. We identify E2A as a mutant KRAS–dependent mediator of resistance to TGF‐β–induced apoptosis. TGF‐β induces E2A via SMAD3 in mutant KRAS cells, and E2A silencing restores apoptosis and enhances radiation response in cell lines ...
Sergei Chuikov +3 more
wiley +1 more source