Results 21 to 30 of about 84,287 (302)
Machine Perfusion for ‘Marginal’ Liver Grafts [PDF]
American Journal of Transplantation, 2008 Due to the critical shortage of deceased donor grafts, clinicians are continually expanding the criteria for an acceptable liver donor to meet the waiting list demands. However, the reduced ischemic tolerance of those extended criteria grafts jeopardizes organ viability during cold storage.
Dutkowski, P +2 more
openaire +2 more sources
Role of perfusion machines in the setting of clinical liver transplantation. A qualitative systematic review [PDF]
, 2018 Growing enthusiasm around machine perfusion (MP) in clinical liver transplantation (LT) may be the preamble for standardized practice to expand the donors' pool.
Lai, Quirino +5 more
core +1 more source
Data science of stroke imaging and enlightenment of the penumbra. [PDF]
, 2015 Imaging protocols of acute ischemic stroke continue to hold significant uncertainties regarding patient selection for reperfusion therapy with thrombolysis and mechanical thrombectomy.
Liebeskind, David S +2 more
core +2 more sources
Machine Perfusion of Lungs [PDF]
Current Transplantation Reports, 2019 The purpose of this review is to summarize the fundamentals, rationale, research topics, and clinical outcomes of ex vivo lung perfusion. Since the first clinical case in 2000, the usefulness of ex vivo lung perfusion to increase the donor lung pool has been supported by much evidence.
Toshihiro Okamoto +5 more
openaire +1 more source
Current Directions in Biomedical Engineering, 2023 Research showed that the normothermic machine perfusion of kidneys can enable prolonged storage and improve conditions compared to traditional cold storage. For research in this area, there is a demand for a long-term in vitro perfusion setup.
Wiartalla Marc +6 more
doaj +1 more source
Viability Criteria during Liver Ex-Situ Normothermic and Hypothermic Perfusion
Medicina, 2022 With the increased use of extended-criteria donors, machine perfusion became a beneficial alternative to cold storage in preservation strategy for donor livers with the intent to expand donor pool. Both normothermic and hypothermic approach achieved good
Fabio Melandro +6 more
doaj +1 more source
Subnormothermic Perfusion in the Isolated Rat Liver Preserves the Antioxidant Glutathione and Enhances the Function of the Ubiquitin Proteasome System. [PDF]
, 2016 The reduction of oxidative stress is suggested to be one of the main mechanisms to explain the benefits of subnormothermic perfusion against ischemic liver damage. In this study we investigated the early cellular mechanisms induced in isolated rat livers
Alva, Norma +4 more
core +4 more sources
A new liver perfusion and preservation system for transplantation Research in large animals [PDF]
, 1990 A kidney perfusion machine, model MOX-100 (Waters Instruments, Ltd, Rochester, MN) was modified to allow continuous perfusion of the portal vein and pulsatile perfusion of the hepatic artery of the liver. Additional apparatus consists of a cooling system,
A. Jake Demetris +17 more
core +1 more source
Analyzing the human liver vascular architecture by combining vascular corrosion casting and micro-CT scanning: a feasibility study [PDF]
, 2014 Although a full understanding of the hepatic circulation is one of the keys to successfully perform liver surgery and to elucidate liver pathology, relatively little is known about the functional organization of the liver vasculature.
Casteleyn, Christophe +6 more
core +1 more source
Metabolites, 2019 There continues to be significant debate regarding the most effective mode of ex situ machine perfusion of livers for transplantation. Subnormothermic (SNMP) and normothermic machine perfusion (NMP) are two methods with different benefits.
Negin Karimian +10 more
doaj +1 more source