Results 31 to 40 of about 2,924,807 (328)

Research progress on hepatic machine perfusion [PDF]

International Journal of Medical Sciences, 2021
Nowadays, liver transplantation is the most effective treatment for end-stage liver disease. However, the increasing imbalance between growing demand for liver transplantation and the shortage of donor pool restricts the development of liver transplantation. How to expand the donor pool is a significant problem to be solved clinically.
Gao, Junda, He, Kang, Xia, Qiang, Zhang, Jianjun   +3 more
openaire   +2 more sources

Hypothermic Machine Perfusion in Liver Transplantation - A Randomized Trial.

New England Journal of Medicine, 2021
BACKGROUND Transplantation of livers obtained from donors after circulatory death is associated with an increased risk of nonanastomotic biliary strictures.
R. van Rijn, Ivo J. Schurink, Y. de Vries, A. P. van den Berg, M. Cortés Cerisuelo, S. Darwish Murad, J. Erdmann, N. Gilbo, R. D. de Haas, N. Heaton, B. van Hoek, V. Huurman, I. Jochmans, O. B. van Leeuwen, V. D. de Meijer, D. Monbaliu, W. Polak, J. Slangen, R. Troisi, A. Vanlander, J. de Jonge, R. Porte   +21 more
semanticscholar   +1 more source

Normothermic machine perfusion versus static cold storage in donation after circulatory death kidney transplantation: a randomized controlled trial

Nature Medicine, 2023
Kidney transplantation is the optimal treatment for end-stage renal disease, but it is still severely limited by a lack of suitable organ donors. Kidneys from donation after circulatory death (DCD) donors have been used to increase transplant rates, but ...
S. Hosgood, C. Callaghan, C. Wilson, Laura Smith, J. Mullings, J. Mehew, GC Oniscu, Benedict L. Phillips, L. Bates, M. Nicholson   +9 more
semanticscholar   +1 more source

Hypothermia or Machine Perfusion in Kidney Donors.

New England Journal of Medicine, 2023
BACKGROUND Therapeutic hypothermia in brain-dead organ donors has been shown to reduce delayed graft function in kidney recipients after transplantation.
D. Malinoski, Christina T. Saunders, S. Swain, T. Groat, Patrick R Wood, Jeffrey Reese, Rachel Nelson, Jennifer Prinz, Kate Kishish, Craig Van De Walker, P. Geraghty, Kristine Broglio, C. Niemann   +12 more
semanticscholar   +1 more source

Normothermic Machine Perfusion of Donor Livers for Transplantation in the United States

Annals of Surgery, 2023
Objective: To compare conventional low-temperature storage of transplant donor livers [static cold storage (SCS)] with storage of the organs at physiological body temperature [normothermic machine perfusion (NMP)].
W. Chapman, A. Barbas, A. D’ALESSANDRO, R. Vianna, C. Kubal, P. Abt, C. Sonnenday, R. Barth, Josue Alvarez-Casas, H. Yersiz, D. Eckhoff, Robert Cannon, Y. Genyk, L. Sher, A. Singer, Sandy Feng, G. Roll, A. Cohen, M. Doyle, D. Sudan, D. Al‐Adra, Adeel S Khan, V. Subramanian, N. Abraham, K. Olthoff, A. Tekin, Lynn Berg, C. Coussios, Chris Morris, L. Randle, P. Friend, S. Knechtle   +31 more
semanticscholar   +1 more source

Machine Perfusion for ‘Marginal’ Liver Grafts [PDF]

American Journal of Transplantation, 2008
Due to the critical shortage of deceased donor grafts, clinicians are continually expanding the criteria for an acceptable liver donor to meet the waiting list demands. However, the reduced ischemic tolerance of those extended criteria grafts jeopardizes organ viability during cold storage.
Dutkowski, P, de Rougemont, O, Clavien, P A   +2 more
openaire   +2 more sources

Role of perfusion machines in the setting of clinical liver transplantation. A qualitative systematic review [PDF]

, 2018
Growing enthusiasm around machine perfusion (MP) in clinical liver transplantation (LT) may be the preamble for standardized practice to expand the donors' pool.
Lai, Quirino, Melandro, Fabio, Mennini, Gianluca, Pugliese, Francesco, Rossi, Massimo, Ruberto, Franco   +5 more
core   +1 more source

Introducing Machine Perfusion into Routine Clinical Practice for Liver Transplantation in the United States: The Moment Has Finally Come

Journal of Clinical Medicine, 2023
While adoption of machine perfusion technologies into clinical practice in the United States has been much slower than in Europe, recent changes in the transplant landscape as well as device availability following FDA approval have paved the way for ...
K. Croome
semanticscholar   +1 more source

A new liver perfusion and preservation system for transplantation Research in large animals [PDF]

, 1990
A kidney perfusion machine, model MOX-100 (Waters Instruments, Ltd, Rochester, MN) was modified to allow continuous perfusion of the portal vein and pulsatile perfusion of the hepatic artery of the liver. Additional apparatus consists of a cooling system,
A. Jake Demetris, Belzer F O, Denmark S W, Greenway C V, Guy Lebeau, Hoffmann R M, Jamieson N V, Katsuhiko Yanaga, Leonard Makowka, Mitsuo Shimada, Moore F D, Ruey Rong Hwang, Saburo Kakizoe, Starzl T E, Starzl T E, Starzl T E, Thomas E. Starzl, Williams J W   +17 more
core   +1 more source

Immune cell dynamics deconvoluted by single-cell RNA sequencing in normothermic machine perfusion of the liver

Nature Communications, 2023
Normothermic machine perfusion (NMP) has emerged as an innovative organ preservation technique. Developing an understanding for the donor organ immune cell composition and its dynamic changes during NMP is essential.
T. Hautz, S. Salcher, M. Fodor, G. Sturm, S. Ebner, A. Mair, M. Trebo, G. Untergasser, S. Sopper, B. Cardini, A. Martowicz, J. Hofmann, S. Daum, M. Kalb, T. Resch, F. Krendl, A. Weissenbacher, G. Otarashvili, P. Obrist, B. Zelger, D. Öfner, Z. Trajanoski, J. Troppmair, R. Oberhuber, A. Pircher, D. Wolf, S. Schneeberger   +26 more
semanticscholar   +1 more source