Results 31 to 40 of about 7,726,210 (354)

Predicting Chronicity in Children and Adolescents With Newly Diagnosed Immune Thrombocytopenia at the Timepoint of Diagnosis Using Machine Learning‐Based Approaches

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Objectives To identify predictors of chronic ITP (cITP) and to develop a model based on several machine learning (ML) methods to estimate the individual risk of chronicity at the timepoint of diagnosis. Methods We analyzed a longitudinal cohort of 944 children enrolled in the Intercontinental Cooperative immune thrombocytopenia (ITP) Study ...
Severin Kasser, Alice Bizeul, Meera Chitlur, Hugo Donato, Jelena Roganovic, Julia E. Vogt, Thomas Kühne   +6 more
wiley   +1 more source

Mechanical property changes of gear surfaces in high-speed hobbing

Nihon Kikai Gakkai ronbunshu
In recent years, high-precision gears are expected to be used in vehicles and robots. Currently, gear hobbing is widely used as a roughing process while shaving and grinding are used as finishing processes to improve the accuracy and surface quality of ...
Yuki UEDA, Noriyuki SAKURAI, Tatsuro TAKAGI, Kazuyuki ISHIZU, Jiwang YAN   +4 more
doaj   +1 more source

Effects of Cooling Systems on the Thermal Behaviour of Machine Tools and Thermal Error Models

Journal of Machine Engineering, 2020
Today, cooling systems are increasingly applied to the structure of machine tools (MT). Unfortunately, to date there have been few efforts to precisely control these cooling systems, which inhibits the full utilisation of their potential to improve MT ...
Martin Mareš, Otakar Horejš, Štěpán Fiala, Lukáš Havlík, Petr Stříteský   +4 more
doaj   +1 more source

Reciprocal control of viral infection and phosphoinositide dynamics

FEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

In-Process Monitoring of Changing Dynamics of a Thin-Walled Component During Milling Operation by Ball Shooter Excitation

Journal of Manufacturing and Materials Processing, 2020
During the milling of thin-walled workpieces, the natural frequencies might change radically due to the material removal. To avoid resonant spindle speeds and chatter vibration, a precise knowledge of the instantaneous modal parameters is necessary. Many
Daniel Bachrathy, Adam K. Kiss, Attila Kossa, Szabolcs Berezvai, David Hajdu, Gabor Stepan   +5 more
doaj   +1 more source

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

FEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes, Guilherme M. Azevedo, Amanda P. Barcellos, Diana Bahia   +3 more
wiley   +1 more source

Study on the properties and mechanism of magnesium alloy and Ni-plating stainless-steel by ultrasonic-laser welding-brazing

Scientific Reports
This study aims to provide a new process to improve the welding performance of steel/magnesium dissimilar materials, using an ultrasonic-laser welding-brazing method to joints AZ31B magnesium alloy on 304 stainless steel.
Bing Wang, Zhan Cheng, Haijun Xu, Yu Wang, Lingjie Luo, Shengxi Wang, Weimin Long, Shizhong Wei   +7 more
doaj   +1 more source

Compensation for spindle’s axial thermal growth based on temperature variation on vertical machine tools

Advances in Mechanical Engineering, 2016
A new spindle’s axial thermal growth model based on temperature variation is proposed considering the limitations of spindle’s axial thermal growth model based on rotating speed.
Kuo Liu, Fei Chen, Tiejun Zhu, Yuliang Wu, Mingjia Sun   +4 more
doaj   +1 more source

Rapid Machine Tool Verification [PDF]

Procedia CIRP, 2014
AbstractThis paper describes work carried out to develop methods of verifying that machine tools are capable of machining parts to within specification, immediately before carrying out critical material removal operations, and with negligible impact on process times.
Muelaner, J. E., Yang, B. R., Davy, C., Verma, M. R., Maropoulos, P. G.   +4 more
openaire   +3 more sources

Interplay between circadian and other transcription factors—Implications for cycling transcriptome reprogramming

FEBS Letters, EarlyView.
This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley   +1 more source