Results 61 to 70 of about 8,269,511 (303)

Secure data storage and service automation for cyber physical production systems through distributed ledger technologies

Journal of Machine Engineering, 2021
In this paper, we use the blockchain technology to design a prototype to secure process data from a 3D-printer. Datastreams are gathered from various sources such as OPC UA servers and autonomous retrofit sensor nodes.
Gordon Lemme, Kilian Armin Nölscher, Erhao Bei, Christian Hermeling, Steffen Ihlenfeldt   +4 more
doaj   +1 more source

Next‐generation proteomics improves lung cancer risk prediction

Molecular Oncology, EarlyView.
This is one of very few studies that used prediagnostic blood samples from participants of two large population‐based cohorts. We identified, evaluated, and validated an innovative protein marker model that outperformed an established risk prediction model and criteria employed by low‐dose computed tomography in lung cancer screening trials.
Megha Bhardwaj, Clara Frick, Ben Schöttker, Bernd Holleczek, Hermann Brenner   +4 more
wiley   +1 more source

Investigation of Tool Cooling and Heat Transfer Using Computational Fluid Dynamics Simulations

Journal of Machine Engineering
Thermal errors remain one of the biggest challenges for the precision of cutting machine tools. Aside from optimizations in the machine tool design and behaviour, optimal cutting process parameters and targeted usage of cutting fluid or alternative ...
Christian Naumann, Claus-Dieter Schmidt, Alexander Geist, Steffen Brier, Janine Glanzel, Philipp Klimant, Steffen Ihlenfeldt, Martin Dix   +7 more
doaj   +1 more source

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

Molecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat, Aslihan Kucuk, Omer Erdogan, Samed Ozer, Bensu Kozan, Tugba Cuceli, Erkan Gumus, Evrim Cevik, Ozge Cevik   +8 more
wiley   +1 more source

A Review of Artificial Intelligence Algorithms Used for Smart Machine Tools

Inventions, 2018
This paper offers a review of the artificial intelligence (AI) algorithms and applications presently being used for smart machine tools. These AI methods can be classified as learning algorithms (deep, meta-, unsupervised, supervised, and reinforcement ...
Chih‐Wen Chang, H. Lee, Chein-Hung Liu
semanticscholar   +1 more source

RaMBat: Accurate identification of medulloblastoma subtypes from diverse data sources with severe batch effects

Molecular Oncology, EarlyView.
To integrate multiple transcriptomics data with severe batch effects for identifying MB subtypes, we developed a novel and accurate computational method named RaMBat, which leveraged subtype‐specific gene expression ranking information instead of absolute gene expression levels to address batch effects of diverse data sources.
Mengtao Sun, Jieqiong Wang, Shibiao Wan
wiley   +1 more source

Machine vision in manufacturing SMEs: a review

Discover Applied Sciences
Automating manufacturing tasks, such as quality control, fault detection, part classification, and inventory management with machine vision systems can significantly improve process efficiency, accuracy, and productivity.
Jonas Werheid, Hannes Behnen, Jan-Henrik Woltersmann, Shengjie He, Tobias Hamann, Anas Abdelrazeq, Robert H. Schmitt   +6 more
doaj   +1 more source

Concept of Integrating a Hybrid Thermal Error Compensation Into an Existing Machine Tool Control Architecture

Journal of Machine Engineering
Thermal error compensation via a numeric control (NC) system is a proven option for upgrading the precision of machine tools. The main advantage is the generally cost-effective application, as no changes to the machine design are necessary. Since modern
Alexander Geist, Muhammad Faisal Yaqoob, Christian Friedrich, Christian Naumann, Steffen Ihlenfeldt   +4 more
doaj   +1 more source

Investigation of the material separation behaviour of rocks using scratch tests for the design of tool grinding processes

SN Applied Sciences, 2022
Article Highlights Investigating material removal mechanisms of rocks against the background of tool grinding. Identifying optima of cutting speed and single grain chip thickness for ductile material removal for rocks.
Berend Denkena, Bernd Breidenstein, Benjamin Bergmann, Philipp Wolters   +3 more
doaj   +1 more source

Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers

Molecular Oncology, EarlyView.
This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel, Peyman Zarrineh, Nathnael T. Tuffa, Jigar H. Sheth, Sumitra Mohan, Mudassar Iqbal, Sankari Nagarajan   +6 more
wiley   +1 more source