The systematic use of cost-effectiveness criteria to inform decisions about the removal of items from publicly-financed 'benefits packages'. A report commissioned by the Department of Health and prepared by the London School of Hygiene and Tropical Medicine [PDF]
, 2007 Ettelt, S, Mays, N, Nolte, E, Thomson, S
core +4 more sources
Infection of wild and laboratory animals with Machupo and Latino viruses.
Bulletin of the World Health Organization, 1976 Natural infection with Machupo and Latino viruses occurs only in the cricetine rodent Calomys callosus. Machupo virus induces fatal infection in suckling mice and hamsters, and in adult guinea-pigs, marmosets, and rhesus monkeys. Latino virus kills only suckling hamsters; it produces chronic but non-viraemic infection in Calomys rodents.Machupo virus ...
P A, Webb, G, Justines, K M, Johnson
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High throughput screening for SARS-CoV-2 inhibitors targeting 5 helix bundle
SLAS DiscoverySARS-CoV-2 and other related viruses enter host cells via receptor recognition and membrane fusion. A crucial part of this is mediated by 5HB which is capable of binding to the viral spike heptad repeats (HR2) making 5HB a potential druggable target of ...
Emery Smith +6 more
doaj +1 more source
[Monoclonal antibodies to the Machupo virus: their isolation and preliminary characteristics].
Voprosy virusologii, 1992 Six monoclonal antibody-producing hybridoma cell lines were generated by fusion of NS-1 myeloma cells with BALB/c immune splenocytes. Monoclonal antibodies (MCA) specific to Machupo virus NP protein were used to study cross-reactivity between pathogenic and nonpathogenic arenaviruses. It was shown that 3140 MCA cross-reacted in IFA with Lassa, Tacaribe,
I V, Malakhova +5 more
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PLoS PathogensSeveral Old World and New World Mammarenavirus are responsible for hemorrhagic fever in humans. These enveloped viruses have a bi-segmented ambisense RNA genome that encodes four proteins.
Xavier Carnec +7 more
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Recent Discoveries of Novel Mammarenaviruses Infecting Humans and Other Mammals in Asia and Southeast Asia. [PDF]
Virulence, 2023 Flannery B, Cain M, Ly H.
europepmc +1 more source
Las «enfermedades emergentes» en las postrimerías del siglo XX: El sida [PDF]
Sin ...
Arrizabalaga, Jon
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[Experimental infection caused by Machupo virus in intact and immunosuppressed albino mice].
Voprosy virusologii, 1990 Features of the course of experimental infection in white mice caused by Machupo virus in relation to their age, route of virus inoculation, and under conditions of normal and suppressed immune response created by antithymocyte globulin (ATG) were studied.
S V, Orlova, V I, Votiakov
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Ophthalmic implications of biological threat agents according to the chemical, biological, radiological, nuclear, and explosives framework. [PDF]
Front Med (Lausanne), 2023 Curran EH +8 more
europepmc +1 more source
[Effect of actinomycin D on the reproduction of the Machupo virus].
Voprosy virusologii, 1985 The effect of inhibitors of mRNA synthesis (actinomycin D and alpha-amanitin) and DNA replication (mitomycin C and ethidium bromide) on Machupo virus reproduction was studied. Actinomycin D (1.0-4.0 micrograms/ml) and alpha-amanitin (10.0 micrograms/ml) added immediately after adsorption reduced the infectious virus titre by 2 lg or more. Actinomycin D
I S, Lukashevich +2 more
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