Results 151 to 160 of about 29,916 (207)
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The macrocyclic effect in tetraaza-macrocyclic ligands

Inorganica Chimica Acta, 1980
Abstract The origin of the Macrocyclic Effect [1] in complexes of cyclam as compared with those of its open-chain analogue 2,3,2- tet is discussed. It is not readily apparent that the presence of four secondary (2°) nitrogens in cyclam , as opposed to two primary (1°) and two 2° in 2,3,2- tet should make much difference, since the pK a 's of 2 ...
R.D. Hancock, G.J. McDougall
openaire   +1 more source

Reversible Macrocycle-to-Macrocycle Interconversion Driven by Solvent Selection

Journal of the American Chemical Society, 2023
Macrocycle-to-macrocycle interconversions are of interest because they can allow access to a variety of structures. However, reversible interconversion between different sized macrocycles remains challenging to control. Herein, we report a facile one-pot synthesis of a series of self-assembled macrocycles from readily prepared α,α'-linked oligopyrrolic
Fei Wang   +7 more
openaire   +2 more sources

Macrocyclic Proteasome Inhibitors

Current Medicinal Chemistry, 2011
Proteasome inhibitors have proven to be effective anticancer agents. Despite the success of the first on the market proteasome inhibitor bortezomib in chemotherapy, alternative clinically useful proteasome inhibitors are still urgently needed as bortezomib therapy causes severe side effects and is limited by arising drug resistance.
Krahn, D., Ottmann, C., Kaiser, Markus
openaire   +3 more sources

Application of Ruthenium-Induced Macrocyclization for the Construction of Macrocyclic Depsipeptides

The Journal of Organic Chemistry, 2002
The synthesis of a biaryl ether containing macrocyclic depsipeptide 1 was achieved in 6% overall yield. The desired macrocycle was constructed by cyclization of a phenol into eta(6)-ruthenium complex. The ruthenium metal was subsequently photolytically deprotected to obtain the macrocycle 1.
Srikanth, Venkatraman   +3 more
openaire   +2 more sources

Macrocycle Drugs Serve Up New Opportunities

Nature Reviews Drug Discovery, 2023
Katie Kingwell
exaly  

Synthetic Macrocycle-Based Nonporous Adaptive Crystals for Molecular Separation

Angewandte Chemie - International Edition, 2021
Ying-Wei Yang, Jia-Rui Wu
exaly  

Significant Fluorescence Enhancement of Zn2+ by Schiff Base Macrocycle

Journal of Photochemistry and Photobiology A: Chemistry, 2022
Makoto Miyasaka
exaly  

High-Yield Synthesis of a Novel Water-Soluble Macrocycle for Selective Recognition of Naphthalene

Chinese Chemical Letters, 2021
Guang-Chuan Ou, Fei Zeng, Man-Hua Ding
exaly  

Hydrocarbon Macrocycle Conformer Ensembles and 13C-NMR Spectra

Angewandte Chemie - International Edition, 2022
Stefan Grimme, Fabian Bohle
exaly  

Corona[5]Arenes Accessed by a Macrocycle-to-Macrocycle Transformation Route and a One-Pot Three-Component Reaction

Angewandte Chemie - International Edition, 2017
Mei-Xiang Wang, Qing-Hui Guo
exaly  

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