Results 81 to 90 of about 13,257 (251)

Parallel Synthesis of Peptide-Like Macrocycles Containing Imidazole-4,5-dicarboxylic Acid

Molecules, 2012
We prepared a series of peptide-like 14-membered macrocycles containing an imidazole-4,5-dicarboxylic acid scaffold by using known coupling reagents and protecting group strategies.
Paul W. Baures, Kraig A. Wheeler, Zhigang Xu   +2 more
doaj   +1 more source

Macrocycles

Drug Discovery Today: Technologies, 2018
Macrocycles are an emerging and largely underexploited part of chemical space where potential drugs for difficult genomic targets can be discovered. Macrocycles can have advantages over their natural twins such as better control over synthesis, physicochemical properties and target binding.
Abdelraheem, Eman M.M., Shaabani, Shabnam, Dömling, Alexander   +2 more
openaire   +1 more source

Late‐Stage Functionalization of Peptides on the Solid Phase

Angewandte Chemie International Edition, EarlyView.
Peptide modifications are essential to control pharmacodynamic and pharmacokinetic properties of peptide drugs. Consequently, strategies that allow for efficient and rapid incorporation of non‐canonical modifications into peptides in parallel formats are highly sought after.
Marius Werner, Truc Lam Pham, Franziska Thomas   +2 more
wiley   +1 more source

Supramolecular Detoxification Approach of Endotoxin Through Host–Guest Complexation by a Giant Macrocycle

Molecules
In Gram-negative bacteria, lipopolysaccharides (LPSs, also known as endotoxin) can induce extensive immune responses that will enable victims to produce severe septic shock syndrome.
Junyi Chen, Xiang Yu, Shujie Lin, Zihan Fang, Shenghui Li, Liguo Xie, Zhibing Zheng, Qingbin Meng   +7 more
doaj   +1 more source

Introduction: Macrocycles [PDF]

Chemical Reviews, 2019
openaire   +2 more sources

Anthropometric Profile and Position-Specific Changes in Segmental Body Composition of Professional Football Players Throughout a Training Period

Sports
Body and anthropometric profiles of football players vary depending on the physiological and technical demands imposed by different positions. The aim of this study was to evaluate the body composition of professional soccer players in relation to their ...
Wiktoria Staśkiewicz-Bartecka, Karolina Krupa-Kotara, Mateusz Rozmiarek, Ewa Malchrowicz-Mośko, Mateusz Grajek, Saioa Agirre Elordui, Jokin Urriolabeitia Razkin, Arkaitz Castañeda Babarro   +7 more
doaj   +1 more source

Shedding Light on Synthetic Autocatalysis: From Conventional Closed‐Shell Chemistries to Overlooked Open‐Shell Occurrences

Chemistry – A European Journal, EarlyView.
Why add another catalyst when the product itself holds the power to catalyze its own formation? Autocatalysis in synthetic chemistry enhances reaction efficiency and uncovers novel catalytic behavior across both closed‐shell and open‐shell systems, expanding reactivity and enabling innovative design strategies.
Jaspreet Kaur, Joshua P. Barham
wiley   +1 more source

Substituent‐Driven Anion‐Binding Selectivity in Aliphatic Chain‐Substituted 1,2‐Phenylene Urea Macrocycles and Optimized Synthetic Methodology

ChemistryOpen
1,2‐Phenylene tetraurea macrocycles recently attracted attention as self‐assembled channel‐making compounds with high selectivity to chlorides. Here, we report on the introduction of aliphatic chains in the periphery of the 1,2‐phenylene tetraurea ...
Kateřina Svobodová, Václav Eigner, Andrea Brancale, Petra Cuřínová, Michal Himl   +4 more
doaj   +1 more source

Synthesis and Characterization of New Macrocyclic Polyether-Diester Ligands Containing A 4H-Pyran-4-One Subcyclic Unit [PDF]

Iranian Journal of Chemistry & Chemical Engineering, 1999
New macrocyclic polyether-diester ligands (3-5) containing the 4H-pyran-4-one subcyclic unit have been prepared by treating various glycols with dimethyl chelidonate (10).
Aziz Shahrisa, Reza Tabrizi
doaj  

Eco‐Friendly Synthesis of Cobalt Phthalocyanine for High‐Efficiency CO2${\rm CO}_{2}$ Electroreduction

Chemistry – A European Journal, EarlyView.
A sustainable synthesis of cobalt phthalocyanine (CoPc) using low‐impact solvents yields high‐performance electrocatalysts with reduced waste (E‐factor 18.6). When integrated into gas diffusion electrodes, CoPc achieves up to 12% Faradays efficiency for CO2‐to‐methanol and 65% CO2‐to‐CO conversion, aligning with state‐of‐the‐art materials and enabling ...
Gloria Zanotti, Federica Palmeri, Venanzio Raglione, Abdolhamid Khodadadi, Camille Tabaries, Jerome Capitolis, Mathieu Prevot, Laurent Piccolo, Mahmoud Zendehdel, Roberto Flammini, Giorgio Contini   +10 more
wiley   +1 more source