Mechanisms of haemoglobin mass expansion following heat stress
Abstract figure legend Theorised mechanisms of heat stress‐induced erythropoiesis which may facilitate the expansion of haemoglobin mass. A, acute: heat stress‐induced renal ischaemia. Redistribution of blood flow away from the kidneys to facilitate thermoregulation during heat stress could reduce renal oxygen delivery, subsequently lowering renal PO2${
Elliott J. Jenkins +4 more
wiley +1 more source
Advances in large DNA fragment assembly for microbial cell factory engineering
Abstract The efficient, rapid, and reliable assembly of DNA fragments is essential for advancing metabolic engineering and synthetic biology. With the rapid advancement of DNA synthesis and assembly technologies, the scale of DNA assembly has expanded from single genes to metabolic pathways and even genomes.
Yu Zhang +5 more
wiley +1 more source
Dynamic Covalent Platform for Chiroptically Tunable Figure-Eight Macrocycles from Preorganized Alkaloidal Scaffolds. [PDF]
Murakami S +7 more
europepmc +1 more source
A benzo‐21‐crown‐7 BODIPY dye (fluorescent probe) serves as a highly selective fluorescent probe for Ba2+ in aqueous solution. Ba2+ binding triggers a strong fluorescence enhancement, enabling sensitive detection with high selectivity, pH stability, and robustness under prolonged illumination.
Thomas Schwarze +3 more
wiley +1 more source
Orthogonal cation and anion template-directed synthesis of a heteroditopic [3]catenane for ion-pair recognition. [PDF]
Tay HM +3 more
europepmc +1 more source
Engineered Metal–Organic Frameworks‐Based Materials for Environmental Detection
Engineered metal–organic frameworks (MOFs) regulated by various material modification strategies are discussed for environmental contaminant detection under different sensing mechanisms, providing future improvements of MOFs in environmental detection. Sensitive and selective detection of contaminants is crucial for environmental protection.
Pan Gao +3 more
wiley +1 more source
Enhancing the Predictive Power of Macrocyclic Drug Permeability by Knowledge Distillation from Analogous Pretraining Data. [PDF]
Zhang Y, Pentikäinen OT.
europepmc +1 more source
An Exploration of Vinamidinium Salts for Frame‐Shifted Synthesis
Oligoheterocycles are widely used in drug discovery and materials science, where they serve as attractive alternatives to peptide fragments. There is strong interest in understanding the structural correspondence between heterocycles and amino acid motifs to recapitulate key binding elements while improving metabolic stability.
Morgan J. Cordell +3 more
wiley +1 more source
A Versatile Strategy for Head-to-Tail Macrocyclization and Traceless Backbone Editing of Short Peptides. [PDF]
Wall BJ +4 more
europepmc +1 more source
From Prebiotic Catalysts to Modern Applications: How Early Catalysts Inspire Today's Innovations
Simple catalytic systems that may have operated under prebiotic conditions offer useful molecular principles for the design of modern functional materials. By examining how amino acids, peptide assemblies, and metal complexes achieve catalysis through simple chemical features, this review highlights how prebiotic chemistry can inspire new strategies ...
Omer Agazani, Meital Reches
wiley +1 more source

