A Chiral Saddle‐Shaped Nanographene With Two Heptagon‐Embedded [4]Helicenes
Angewandte Chemie International Edition, EarlyView.We present a novel synthetic strategy toward a chiral saddle‐shaped nanographene (cSNG) via a two‐step oxidation of a prochiral anthracene precursor. The Scholl‐type oxidation first yields a key intermediate with sp3‐defect heptagons, and subsequent oxidative dehydrogenation affords fully conjugated cSNG.
Felix Trautner +11 more
wiley +1 more source
Late‐Stage Functionalization of Peptides on the Solid Phase
Angewandte Chemie International Edition, EarlyView.Peptide modifications are essential to control pharmacodynamic and pharmacokinetic properties of peptide drugs. Consequently, strategies that allow for efficient and rapid incorporation of non‐canonical modifications into peptides in parallel formats are highly sought after.
Marius Werner +2 more
wiley +1 more source
Radioimmunotherapy with Yttrium Macrocycles [PDF]
, 1994 Monoclonal antibody fragments (Fab') which recognise tumour-associated antigens provide an ingenious means of selectively targeting a therapeutic radionuclide to a tumour for radioimmunotherapy.
Norman,
core
Synthesis of Macrocyclic Compounds Using Oxidative Radical Cyclization
, 2008 Manganese(III)-based oxidative free-radical macrocyclization was examined. α,α,ω,ω-Tetraaryl-α,ω-alkadienes 1x (x = 6, 8, 12, 16, 18, 28) and oligomethylene bis(3-oxobutanoate)s 2y (y = 6, 10, 12, 16, 20, 26) were allowed to react with manganese(III ...
ニシノ, ヒロシ +5 more
core +1 more source
Macrocyclic polyether sulfide syntheses :|bthe preparation of thia-crown-6, 7, and 8 compounds
, 1975 Macrocyclic polyether sulfides have been prepared by reacting an oligoethylene glycol dichloride with a dithiol in refluxing basic ethanol. The following new compounds were prepared: 1,5-dithia-(19- crown-6), 3-hydroxy-1,5-dithia-(19-crown-6), 1,4-dithia-
Reeder, Robert Askew
core
Targeting of mitochondria-endoplasmic reticulum by fluorescent macrocyclic compounds.
, 2011 BACKGROUND: Useful probes of the intracellular environment that target a specific organelle in order to allow direct observation of the changes in these regions is of high current interest.
Luiza Breitenfeld +6 more
core +1 more source
Syntheses of Acyclic and Macrocyclic Compounds Derived from 9,9-Diethylfluorene (Part I). [PDF]
ChemistryOpen, 2020 Seidel P, Mazik M.
europepmc +1 more source
PROGRESS IN THE TOTAL SYNTHESIS OF SPIROLIDE C AND A MODEL SYSTEM OF A KEY DIELS-ALDER MACROCYCLIZATION [PDF]
, 2013 Spirolode C is a macrocyclic marine toxin produced by the dinoflagellate Alexandrium ostenfeldii that has attracted significant synthetic interest due in particular to its rare spirocyclic imine fragment.
Bencivenga, Anthony
core
A CONVENIENT METHOD FOR THE SYNTHESIS OF MACROCYCLIC TETRAESTER COMPOUNDS.
, 1987 A new simple and efficient method for the synthesis of macrocyclic tetraesters, consisiting in the treatment of 1,3-benzodioxolic or 1,3-benzoxathiolic compounds with diacyl dichlorides in the presence of MgBr2 or NaI as catalysts is ...
Podda G. +3 more
core
MACROCYCLIC POLYETHER-DIESTER COMPOUNDS AS PHASE-TRANSFER CATALYSTS
, 1988 Three new macrocyclic polyether-diester have been prepared. The catalytic activity of these compounds has been tested in the Вr/I exchange reactions of octyl bromide with different ionic diameter ...
Podda G. +4 more
core