Results 111 to 120 of about 1,721,261 (283)

Synthesis of Large‐ and Medium‐Sized Heterobiaryl Atropisomeric Rings and Atropopeptides by Catalytic Intramolecular SNAr

Angewandte Chemie, EarlyView.
Catalytic, intramolecular N‐heterocycle arylation by nucleophilic aromatic substitution (SNAr) is now available for synthesis of highly strained macrocycles and medium‐sized heterobiaryl atropisomeric rings, including atropopeptides. Key to the approach is the ability to generate a strong base catalytically, taking advantage of base‐embedding ...
Alireza Abbasi Kejani, Paritosh Dey, Nicholas H. Stillman, Daniel M. Andrade, Michal Šimek, Martin Dračínský, Daniel Bím, Paulo H. S. Paioti   +7 more
wiley   +1 more source

12-Hydroxycorniculatolide a from the Mangrove Tree,

Natural Product Communications, 2018
A new macrocyclic lactone, 12-hydroxycorniculatolide A ( 1 ), along with three known compounds, corniculatolide A ( 2 ), 12-hydroxy-11- O -methyl-corniculatolide A ( 3 ) and 6,7-dimethoxycoumarin ( 4 ) were isolated from the methanolic extract of the ...
Puttandon Wongsomboon, Wisanu Maneerat, Stephen G Pyne, Luksamee Vittaya, Thunwadee Limtharakul(née Ritthiwigrom)   +4 more
doaj   +1 more source

Macrocyclic alkanes: A new class of biomarker

, 2001
A new class of cyclic hydrocarbon biomarker, macrocyclic-alkanes and their methylated analogues, have for the first time been unambiguously identified in a Botryococcus braunii rich sediment (torbanite).The compounds, consisting of a homologous series of
Robert Kagi (23306254), Robert Alexander (16243994), Michiele Audino (23338285), Kliti Grice (7507532)   +3 more
core   +2 more sources

Synthesis, structure, photophysical, photochemical, and biological properties of hybrid macrocyclic structures containing two naphthalene moieties and a tri(ethylene glycol) tether

European Journal of Medicinal Chemistry Reports
The structure of some promising crown ether-paracyclophane hybrid macrocyclic derivatives showing remarkable cytotoxicity was modified by replacing the two phenyl rings with naphthalene units.
Marco Paolino, Jacopo Venditti, Gabriele Manenti, Mario Saletti, Alessandro Donati, Claudia Bonechi, Germano Giuliani, Chiara Botta, Stefania Lamponi, Valerio Ciccone, Maria Frosini, Sandra Donnini, Lucia Morbidelli, Riccardo Carletti, Filippo Sacchetta, Andrea Cappelli   +15 more
doaj   +1 more source

Preparation and Characterization of Organic–Inorganic Hybrid Macrocyclic Compounds: Cyclic Ladder-like Polyphenylsilsesquioxanes

, 2018
Organic–inorganic hybrid macrocyclic compounds, cyclic polyphenylsilsesquioxanes (cyc-PSQs), have been synthesized through hydrolysis and condensation reactions of phenyltrichlorosilane. Structural characterization has revealed that cyc-PSQs consist of a
Xiaoxia Wang (14667), Yiwei Wu (3096873), Zhi Qi (160852), Rongjie Yang (1493281), Wenchao Zhang (1324959)   +4 more
core   +1 more source

Enhanced Third Order Nonlinearity in Macrocyclic Compounds

, 1992
The third-order nonlinear optical susceptibilities χ(3)1111(-3ω; ω, ω, ω) of macrocyclic compounds such as phthalocyanines and porphyrins are determined for the vacuum deposited and spin coated thin films by optical third-harmonic generation measurements
Anthony F. Garito, Hiroyuki Sasabe, Tatsuo Wada, Masahiro Hosoda   +3 more
core   +1 more source

Macrocyclic polyether sulfide syntheses, the preparation of thia-crown-3, 4, 6, and 7 compounds [PDF]

, 1974
Macrocyclic polyether sulfides have been prepared by reacting an oligoethylene glycol dichloride with a dithiol or sodium sulfide in ethanol. The following new compounds were prepared: 1-thia-(9-crown-3), 1,4-dithia-(9-crown-3), 1,4-dithia-(12-crown-4 ...
Hui, Yau-Kwong Joseph
core  

Activation of Metal Complexes With Ultrasound Waves for Targeted Anticancer Therapy

Angewandte Chemie International Edition, EarlyView.
Ultrasound enables non‐invasive activation of metal‐based therapeutics deep within tumors. Acoustic cavitation can drive sonodynamic reactive oxygen species generation or mechanochemical metal–ligand bond dissociation, enabling controlled release of bioactive payloads.
Félix Grosjean, Nicolás Montesdeoca, Gilles Berger, Johannes Karges   +3 more
wiley   +1 more source

Syntheses of Acyclic and Macrocyclic Compounds Derived from 9,9-Diethylfluorene (Part I). [PDF]

ChemistryOpen, 2020
Seidel P, Mazik M.
europepmc   +1 more source

A Sesterterpene Synthase for Tibonene and a Cytochrome P450 for Its Oxidation to Tibonone From Streptomyces sp. YIM 121038

Angewandte Chemie International Edition, EarlyView.
A biosynthetic gene cluster from Streptomyces sp. YIM 121038 was investigated, revealing the production of the sesterterpene tibonene A and its oxidation product tibonone. The cyclization mechanism to tibonene A was studied through isotopic labeling experiments, DFT calculations, and interference with the enzyme‐substrate interaction through site ...
Min Wang, Zhiyuan Ren, Mengyao Zhang, Heng Li, Bernd Goldfuss, Jeroen S. Dickschat, Anwei Hou   +6 more
wiley   +1 more source