Results 201 to 210 of about 25,151 (288)

Sustainable control of cyathostomin infections in practice

Equine Veterinary Education, EarlyView.
Summary Cyathostomins are the most prevalent helminths in horses and are found in nearly all grazing groups. These parasites have been shown to exhibit widespread anthelmintic resistance and can cause clinical disease, so they are a growing concern.
J. B. Matthews, T. S. Mair
wiley   +1 more source

On-Resin Synthesis and Diversification of Macrocyclic Disulfide Bridge Peptidomimetics via Bifunctional 5-Iodo-1,4-Triazoles. [PDF]

J Org Chem
Malone MA, Shepperson OA, Simms JE, Reid AJ, Jamieson AG.   +4 more
europepmc   +1 more source

Tapeworm testing: Coprological and antibody‐based approaches across colic types in a German equine hospital population

Equine Veterinary Education, EarlyView.
Summary Background The association between tapeworm infection and equine colic is established, but gaps remain regarding specific colic types. Objectives To assess the relationship between tapeworm test results and equine colic types: The study aimed to determine if ileocaecal disorders (IC) are more frequently associated with Anoplocephala spp ...
K. L. Adamasky, K. Drozdzewska, P. Schmitz, N. Peczak, K. L. Lightbody, J. B. Matthews, M. K. Nielsen, R. Merle, G. von Samson‐Himmelstjerna, H. Gehlen   +9 more
wiley   +1 more source

Macrocyclic Peptides Containing an Imidazopyridinium (IP⁺) Unit Display Enhanced Passive Cell Permeability. [PDF]

J Am Chem Soc
Li B, Parker J, Briggs S, Dong J, Wang C, Fu CW, Burke JM, Kodadek T.   +7 more
europepmc   +1 more source

The tryptophan prenyltransferase ComQ from Bacillus subtilis 168 can prenylate daptomycin at Trp1

The FEBS Journal, EarlyView.
ComQ168 from Bacillus subtilis 168 catalyzes C‐terminal tryptophan farnesylation of ComX to generate a competence‐inducing pheromone. Recombinant ComQ168 also modifies cyclic peptides, including Daptomycin, likely at the N‐terminal tryptophan. Structural modeling highlights a C‐terminal binding region, supporting substrate promiscuity and establishing ...
Yanli Xu, Maximilian J. L. J. Fürst, Oscar P. Kuipers   +2 more
wiley   +1 more source

Macrocyclic geminal diols: synthesis, structures, stability and photophysical properties. [PDF]

Chem Sci
Zou B, Chen X, Liu H, Wen S, Huang J, Wei H, Huang J, Gu Y, Xu B, Fan J, Jiang HW.   +10 more
europepmc   +1 more source

Pharmacokinetics of Moxidectin in Bare‐Nosed Wombats (Vombatus ursinus) After Intravenous, Sub‐Cutaneous and Transdermal Administration

Journal of Veterinary Pharmacology and Therapeutics, EarlyView.
ABSTRACT The anti‐parasitic drug moxidectin is a frontline treatment for sarcoptic mange in bare‐nosed wombats (Vombatus ursinus), a disease causing significant animal welfare issues and instances of local population declines. Despite widespread usage, knowledge of species‐specific pharmacokinetics of moxidectin in bare‐nosed wombats is still limited ...
E. K. Stott, L. F. Skerratt, T. Whittem, M. Leeming, K. Pillay, G. S. Doran, B. Gardner, M. Lynch, M. Klein, P. Holz, T. Chen, J. Hufschmid, A. P. Woodward   +12 more
wiley   +1 more source

Ribifolones A-H, New Macrocyclic Diterpenes from <i>Jatropha ribifolia</i>, Their Cytotoxic Activity and Insights Supported by Network Pharmacology and Molecular Modeling. [PDF]

Molecules
de Souza TA, Alves AF, de Souza RRM, Albuquerque ACF, Brito TAM, Sobral MV, Dos Santos Júnior FM, Agra MF, Scotti L, Abreu LS, Scotti MT, Tavares JF, da Silva MS.   +12 more
europepmc   +1 more source

Ingestion of attractive toxic sugar baits containing ivermectin before and after blood feeding affects the biology and reproduction of Aedes aegypti (Diptera: Culicidae)

Medical and Veterinary Entomology, EarlyView.
Attractive toxic sugar bait containing ivermectin (ATSB‐IVM) ingestion markedly reduced blood feeding, survival, oviposition, egg production and larval hatching, with the strongest effects when baits were ingested before blood feeding. Timing of ingestion (48–96 h before or after blood feeding) shaped sublethal impacts across the first and second ...
Thais Alves de Moura, Alyne Cunha Alves Dias, Alexandre de Almeida e Silva   +2 more
wiley   +1 more source

Enantioselective Total Synthesis of Two Aromatized Halicyclamines. [PDF]

J Am Chem Soc
Firestone ZD, Grigolo TA, Pernichelle FG, Smith JM.   +3 more
europepmc   +1 more source