Results 21 to 30 of about 113,437 (249)

Establishment of macrocyclic lactone resistant Dirofilaria immitis isolates in experimentally infected laboratory dogs

open access: yesParasites & Vectors, 2014
Background Strains of Dirofilaria immitis suspected of lack of efficacy (LOE) to macrocyclic lactone (ML) preventive drugs have been increasingly reported in dogs by practicing veterinarians since 2005 in the Lower Mississippi Delta region.
Cassan N Pulaski   +14 more
doaj   +2 more sources

De Novo Assembly of the Dirofilaria immitis Genome by Long-Read Nanopore-Based Sequencing Technology on an Adult Worm from a Canine Cardiopulmonary Dirofilariosis Case

open access: yesAnimals, 2022
Dirofilaria immitis is a zoonotic parasitic nematode that infects domestic and wild canids, among its vertebrate hosts. The genetic analysis of D. immitis nowadays transcends the need for genetic taxonomy of nematodes, such as the study of resistance to ...
Sónia Gomes-de-Sá   +7 more
doaj   +1 more source

Comparison of the efficacy of macrocyclic lactone anthelmintics, either singly or in combination with other anthelmintic(s), in nine beef herds in southern NSW.

open access: yesAustralian Veterinary Journal, 2023
Anthelmintic resistance (AR) is a well-recognized challenge in farmed ruminants. The use of anthelmintics in combination is one of the strategies recommended to slow the rate of AR development.
M. Allworth   +5 more
semanticscholar   +1 more source

Effects of macrocyclic lactone anthelmintics on seed germination of temperate grassland species.

open access: yesPlant biology, 2023
Macrocyclic lactone anthelmintics are widely used to control invertebrate pests in livestock, such as sheep. While anthelmintic effects on non-target animals, such as dung-dwelling insects, are well studied, effects on seed germination are largely ...
L. Laber   +4 more
semanticscholar   +1 more source

Macrocyclic lactone resistance in Dirofilaria immitis: risks for prevention of heartworm disease.

open access: yesInternational Journal of Parasitology, 2021
Heartworm disease, caused by Dirofilaria immitis, can be lethal in dogs and cats. It is transmitted by mosquitoes, and occurs in many parts of the world. Prevention relies on macrocyclic lactones (MLs).
R. Prichard
semanticscholar   +1 more source

Diagnosis and control of anthelmintic-resistant Parascaris equorum [PDF]

open access: yesParasites & Vectors, 2009
Since 2002, macrocyclic lactone resistance has been reported in populations of Parascaris equorum from several countries. It is apparent that macrocyclic lactone resistance developed in response to exclusive and/or excessively frequent use of ivermectin ...
Reinemeyer Craig R
doaj   +1 more source

Olefinic-Lactone Cyclizations to Macrocycles [PDF]

open access: yesOrganic Letters, 2008
Olefinic-lactone cyclization reactions that result in the generation of macrocycles are described.
John C, Rohanna, Jon D, Rainier
openaire   +2 more sources

Selamectin Is the Avermectin with the Best Potential for Buruli Ulcer Treatment. [PDF]

open access: yesPLoS Neglected Tropical Diseases, 2015
A comprehensive analysis was done to evaluate the potential use of anti-parasitic macrocyclic lactones (including avermectins and milbemycins) for Buruli ulcer (BU) therapy.
Nicole Scherr   +3 more
doaj   +1 more source

Recording drug responses from adult Dirofilaria immitis pharyngeal and somatic muscle cells

open access: yesInternational Journal for Parasitology: Drugs and Drug Resistance, 2021
Despite being considered one of the most pathogenic helminth infections of companion animals, members of macrocyclic lactone class are the only drugs available for the prevention of heartworm disease caused by Dirofilaria immitis.
S. Verma   +4 more
doaj   +1 more source

Resistance against macrocyclic lactones in Psoroptes ovis in cattle

open access: yesParasites & Vectors, 2020
Background Psoroptic mange is an important disease in Belgian Blue cattle. Treatment failure of macrocyclic lactones against Psoroptes ovis has been reported, but clear evidence of in vivo resistance is lacking.
Wouter van Mol   +6 more
doaj   +1 more source

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