Results 141 to 150 of about 75,061 (261)

Antibiotic‐mediated immune modulation in periodontitis

Periodontology 2000, EarlyView.
Abstract Periodontitis is a chronic inflammatory disease affecting the supporting structures of the teeth. Although initiated by dysbiotic microbial communities, its progression is largely driven by the host's uncontrolled inflammatory response. While antibiotics have conventionally been employed in periodontitis therapy for their antimicrobial ...
Lina J. Suárez, R. M. Arce, Camila Pinheiro Furquim, Cristiane Gonçalves, Alpdogan Kantarci, Magda Feres, Nidia C. Castro dos Santos   +6 more
wiley   +1 more source

Novel and emerging antimicrobial strategies in the management of oral infections

Periodontology 2000, EarlyView.
Abstract Background Antibiotics marked a pivotal turning point in human civilization, enhancing social interactions and extending human life expectancy. In addition to their success in treating systemic infectious diseases, they have significantly improved periodontal treatment outcomes as an adjunct therapy.
Ozge Unlu, Nil Yakar, Alpdogan Kantarci
wiley   +1 more source

Tacrolimus and Hyaluronate Therapy Enhance Tear Film Stability in Canine Evaporative Dry Eye Disease

Veterinary Ophthalmology, EarlyView.
ABSTRACT Objective Evaluate the efficacy of a therapeutic approach combining tacrolimus and hyaluronate‐based lubricant for the management of evaporative dry eye disease (EDED) in dogs, compared to hyaluronate monotherapy. Procedures Fifty‐four client‐owned dogs with EDED were randomly assigned to three groups (n = 18 each): Group 1 received 0.03 ...
Lionel Sebbag, Sirlene F. Barbosa, Arianne P. Oriá   +2 more
wiley   +1 more source

Veterinary antibiotic usage in the Netherlands in 2010 [PDF]

The objective of this study is to obtain detailed insight into the exposure of farm animals to antibiotics, by monitoring both sales data at the national level and more specifically data per animal species.
Bergevoet, R.H.M., Bondt, N., Douma, B.E., Puister-Jansen, L.F., Veen, H.B., van der, Vliet, A.L.J., van, Wehling, K.W.   +6 more
core   +1 more source

Severe and disseminated atypical mycobacteriosis of the skin under immunosuppression

JDDG: Journal der Deutschen Dermatologischen Gesellschaft, EarlyView.
Veronika Zenderowski, Laura Schreieder, Mark Berneburg, Dennis Niebel, Sebastian Haferkamp, Sigrid Karrer, Konstantin Drexler   +6 more
wiley   +1 more source

A comprehensive review of cluster methods for drug–drug interaction network

Quantitative Biology, Volume 14, Issue 1, March 2026.
Abstract The detection of drug–drug interaction (DDI) is crucial to the rational use of drug combinations. Experimentally, DDI detection is time‐consuming and laborious. Currently, researchers have developed a variety of computational methods to predict DDI.
Shuyuan Cao, Guixia Liu, Xiangrun Zhou, Ji Lv   +3 more
wiley   +1 more source

Intrapartum Antibiotic Prophylaxis and Child Health Outcomes: A Systematic Review and Meta‐Analysis of Observational Studies

BJOG: An International Journal of Obstetrics &Gynaecology, Volume 133, Issue 4, Page 556-567, March 2026.
ABSTRACT Background With increasing use of intrapartum antibiotic prophylaxis (IAP) for the prevention of early‐onset Group B streptococcus (GBS) infections, there is concern about its long‐term consequences on child health. Objectives To synthesise the evidence of IAP exposure on autoimmune‐related diseases, obesity in childhood and microbial ...
Maedeh Moradi, Jessica A Grieger, Xiao Tong Teong, Leonie K Heilbronn   +3 more
wiley   +1 more source

Identifying Drugs Associated With Parkinson's Disease Risk Using Machine Learning

Basic &Clinical Pharmacology &Toxicology, Volume 138, Issue 3, March 2026.
ABSTRACT Machine learning (ML)–based methods have been proposed as a potential approach for identifying candidate drugs to be repurposed as disease‐modifying treatments for Parkinson's disease (PD). We applied an ML‐based signal detection method to identify drugs associated with PD and evaluated the method's generalizability.
Eeva Pylkkö, Émeline Courtois, Anne Paakinaho, Sirpa Hartikainen, Valtteri Kaasinen, Alexis Elbaz, Anne C. M. Thiébaut, Ismaïl Ahmed, Anna‐Maija Tolppanen   +8 more
wiley   +1 more source

A retrospective case series of 66 foals with presumed acute interstitial pneumonia

Equine Veterinary Education, Volume 38, Issue 3, Page 143-153, March 2026.
Summary Background There is limited literature describing acute interstitial pneumonia (AIP) in foals. Objectives Description of clinical and ultrasonographic findings in 66 foals affected by AIP. Investigation into whether the number of AIP cases is associated with specific climatic conditions. We also investigated whether clinical, haematological and
L. Weißlein, F. Freise, M. Venner
wiley   +1 more source

The potential value of cytokine, cortisol and vitamin D profiles in foals from birth to weaning for respiratory disease prediction on a farm endemic for Rhodococcus equi pneumonia

Equine Veterinary Journal, Volume 58, Issue 2, Page 359-371, March 2026.
Abstract Background Rhodococcus equi causes pneumonia in young foals, but disease susceptibility and severity vary. Cortisol and vitamin D modulate immune responses and cytokine production during bacterial infection, and altered concentrations are associated with sepsis in neonatal foals. We hypothesised an age and disease effect on circulating steroid
Londa J. Berghaus, Monica Venner, Hannah Helbig, Dorothea Hildebrandt, Kelsey Hart   +4 more
wiley   +1 more source