Results 61 to 70 of about 55,784 (291)

Integration of Nutrition and Organic Agriculture Framework in Managing Gastrointestinal Nematodes in Ruminants

Animal Research and One Health, EarlyView.
Gastrointestinal nematode infections damage the gastrointestinal epithelial tissues of ruminants, affecting nutrient utilization and overall production performance. This review outlines host‐gastrointestinal nematode interactions and discusses integrated control strategies, including nutritional supplementation, grazing management, vaccines, and ...
Wenxun Chen, Xiangfang Tang, Yimin Zhuang, Shengjun Zhao, Ying Ren, Xiaokang Lv   +5 more
wiley   +1 more source

Long-Term Macrolides in Chronic Respiratory Diseases: Dusk or a New Dawn? A Narrative Review

Antibiotics
Macrolides—especially azithromycin—have been increasingly investigated in chronic respiratory diseases for their combined antimicrobial, anti-inflammatory, and immunomodulatory properties.
Daniele Previtero, Gioele Castelli, Ylenia Padrin, Virginia Santello, Daniele Mengato, Davide Biondini, Graziella Turato, Mariaenrica Tiné, Paolo Spagnolo, Umberto Semenzato   +9 more
doaj   +1 more source

Ceftriaxone‐induced liver injury: Incidence, phenotypic characterization and predictive factors

British Journal of Clinical Pharmacology, EarlyView.
Introduction Ceftriaxone is a widely used third‐generation cephalosporin in hospitalized patients. Although generally considered safe, it has been associated with hepatobiliary complications and emerging reports of drug‐induced liver injury (DILI). However, data on its true incidence, phenotypic patterns, and predictors remain limited. This study aimed
Mohamed Hatem, Mohannad N. AbuHaweeleh, Humam Emad Rajha, Mhd Osama Rahhal, Ahmad Hamdan, Lina Naseralallah   +5 more
wiley   +1 more source

Clinical Resistant Strains of Enterococci and Their Correlation to Reduced Susceptibility to Biocides: Phenotypic and Genotypic Analysis of Macrolides, Lincosamides, and Streptogramins

Antibiotics, 2023
Enterococci are troublesome nosocomial, opportunistic Gram-positive cocci bacteria showing enhanced resistance to many commonly used antibiotics. This study aims to investigate the prevalence and genetic basis of antibiotic resistance to macrolides ...
Amr Selim Abu Lila, Tareq Nafea Alharby, Jowaher Alanazi, Muteb Alanazi, Marwa H. Abdallah, Syed Mohd Danish Rizvi, Afrasim Moin, El-Sayed Khafagy, Shams Tabrez, Abdullah Ali Al Balushi, Wael A. H. Hegazy   +10 more
doaj   +1 more source

Macrolides, Reflux and Respiratory Disease

, 2018
Macrolides are a family of compounds that belong to the polyketides class. They are characterised by a large macrocyclic lactone ring that is produced by chain extension of propionates to which one or more sugars (usually cladinose and desosamine) attach.
Tamsin Nash, Crooks, Michael G., Michael G. Crooks, Nash, Tamsin   +3 more
core   +1 more source

The effect of mild and moderate hepatic impairment on the pharmacokinetics, safety and tolerability of balcinrenone

British Journal of Clinical Pharmacology, EarlyView.
Abstract Aim Balcinrenone (previously AZD9977) is a novel selective non‐steroidal mineralocorticoid receptor antagonist (MRA) with a differential mechanism of action relative to approved MRAs. The aim of this trial was to assess the pharmacokinetics, safety and tolerability of balcinrenone in participants with mild and moderate hepatic impairment ...
Anna L. Eriksson, Deeyen Karsanji, Bonifride Tuyishimire, Joanna Parkinson, Maria Heijer, Tadeusz Pawlik, Judith Hartleib‐Geschwindner, Maria Leonsson‐Zachrisson, Hans Ericsson   +8 more
wiley   +1 more source

Distribution of erm genes and low prevalence of inducible resistance to clindamycin among staphylococci isolates

Brazilian Journal of Infectious Diseases
INTRODUCTION: Resistance to macrolides, lincosamides and streptogramins B (MLS B antibiotics) in staphylococci may be due to modification in ribosomal target methylase encoded by erm genes.
Vivian de Lima Spode Coutinho, Rodrigo Minuto Paiva, Keli Cristine Reiter, Fernanda de-Paris, Afonso Luis Barth, Alice Beatriz Mombach Pinheiro Machado   +5 more
doaj   +1 more source

Increase in Pneumococcus Macrolide Resistance, United States

Emerging Infectious Diseases, 2009
During year 6 (2005–2006) of the Prospective Resistant Organism Tracking and Epidemiology for the Ketolide Telithromycin surveillance study, 6,747 Streptococcus pneumoniae isolates were collected at 119 centers.
Stephen G. Jenkins, David J. Farrell
doaj   +1 more source

Regioselective Aldol Reactions Directed by Charge and Orbital Effects in Cyclic Germyl Dienolates: Synthesis of Three Distinct Regio‐ and Stereoisomers

Chemistry – A European Journal, EarlyView.
Charge and orbital control represent fundamental principles in organic chemistry. In this study, these principles are applied to the aldol reactions of a cyclic Ge‐dienolate. By systematically tuning the charge and orbital distributions of the Ge‐dienolates and their aldehyde reaction partners, regio‐ and stereoselective access to three distinct aldol ...
Taishi Nojima, Akihito Konishi, Makoto Yasuda   +2 more
wiley   +1 more source

Changes in macrolide resistance phenotype in pharyngeal group a streptococci isolates in children [PDF]

Medicinski Podmladak, 2018
Introduction: The second drugs of choice for treatment of pharyngitis caused by Streptococcus pyogenes (S.pyogenes; group A streptococcus - GAS) are macrolides.
Vuksanović Pavle, Opavski Nataša
doaj