Results 51 to 60 of about 55,784 (291)

Poly(I:C)‐Activated Nasal Fibroblasts Promote Eosinophil Recruitment in CRSwNP

open access: yesInternational Forum of Allergy &Rhinology, EarlyView.
ABSTRACT Background Chronic rhinosinusitis with nasal polyps (CRSwNP) is characterized by persistent mucosal inflammation and eosinophilic infiltration. Although epithelial and immune cells have been widely studied, the role of nasal fibroblasts in innate immune activation and eosinophil recruitment remains unclear.
Chaewon Shin   +5 more
wiley   +1 more source

Comparative efficacy and safety of clarithromycin in the treatment of bacterial sinusitis

open access: yesМедицинский совет, 2014
Inflammatory pathology of the nasal cavity and paranasal sinuses is one of the major challenges in otorhinolaryngology today. Among patients hospitalized in ENT units, the incidence of inflammatory diseases of the paranasal sinuses is up to 36%.
V. I. Popadyuk   +2 more
doaj   +1 more source

Macrolides at Clinically-Relevant Concentrations May Induce Biofilm Formation in Macrolide-Resistant Staphylococcus aureus

open access: yesAntibiotics, 2023
Macrolides inhibit biofilm formation in several Gram-negative, intrinsically-resistant bacterial species. However, the effect of macrolides upon biofilm formation by susceptible Gram-positive bacteria has been much less explored as such concentrations ...
Carlos F. Amábile-Cuevas
doaj   +1 more source

Immunomodulatory effect of macrolides: At what cost? [PDF]

open access: yes, 2016
We present the case of a 60-year old female patient, with a 10 year history of non-CF bronchiectasis and use of macrolides as maintenance immunomodulatory treatment, who was diagnosed with macrolide-resistant Mycobacterium avium complex lung disease ...
Georgia Pitsiou   +13 more
core   +1 more source

Severe problem of macrolides resistance to common pathogens in China

open access: yesFrontiers in Cellular and Infection Microbiology, 2023
With the widespread use of macrolide antibiotics in China, common pathogens causing children’s infections, such as Streptococcus pneumoniae, Streptococcus (including Group A streptococcus, Group B streptococcus), Staphylococcus aureus, Bordetella ...
Jialin Li   +12 more
doaj   +1 more source

Macrolides: Indications and Contraindications

open access: yes, 2023
Recently, there has been a growing interest in the use of chronic macrolides for the prophylaxis of recurrent exacerbations in severe chronic obstructive pulmonary disease (COPD) patients.
Xavier Pomares
core   +1 more source

Synergistic Advanced Oxidation and Physicochemical Treatment Strategies for Antibiotic Removal and Resistance Mitigation in Water

open access: yesAsia-Pacific Journal of Chemical Engineering, EarlyView.
ABSTRACT The presence of antibiotics in water not only causes environmental pollution but also increases the growth of antibiotic‐resistant bacterial genes, which pose serious threats to human beings and other water residents. Large numbers of people are reportedly affected by the resistant bacterial genes, as many broad‐spectrum antibiotics are not ...
Amir Zada, Shohreh Azizi
wiley   +1 more source

Macrolides: The Plug Is Out [PDF]

open access: yesCell, 2012
Macrolide antibiotics are thought to clog up the ribosomal tunnel and thereby block general protein synthesis. By using a combination of elegant in vivo and in vitro approaches, Kannan et al. show that the inhibitory action of these drugs on bacterial protein synthesis is selective rather than global.
Gamerdinger, Martin, Deuerling, Elke
openaire   +3 more sources

Integrating One Health to Mitigate the Emergence and Spread of Antimicrobial Resistance in Livestock and Aquaculture

open access: yesAnimal Research and One Health, EarlyView.
Antimicrobial resistance (AMR) is an escalating global threat driven by antimicrobial use in aquaculture and livestock. Resistant pathogens and genes can spread across humans, animals, and the environment through interconnected ecosystems. Using a One Health approach, this review emphasizes antimicrobial stewardship, regulatory strengthening, enhanced ...
Mir Mohammad Ali   +10 more
wiley   +1 more source

AZITROMYCIN EFFICACY IN TREATMENT OF PEDIATRIC OUT-OF-HOSPITAL INFECTIONS

open access: yesВопросы современной педиатрии, 2012
Macrolides remain one of the most popular types of antibiotics prescribed in the outpatient’s clinic and also are second most popular after penicillins in the amount of consumption.
L. V. Kozlova
doaj   +1 more source

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