Results 131 to 140 of about 103,280 (234)
Shewanella oneidensis and Bacillus subtilis, both harboring prophages, reveal a novel biosynthetic route to scalable and programmable DNA superstructures in flower‐ and wire‐like shapes, respectively. Activation of prophages is achieved via 3‐hour starvation and monitored using reporter strains.
Gabriel Antonio S. Minero +7 more
wiley +2 more sources
Abstract Macromolecular crowding modulates enzyme behavior in crowder‐ and protein‐specific ways, yet its impact on viral proteases, which are often key therapeutic targets, remains unclear. Here, we investigated the hepatitis C virus NS3/4A protease under increasing concentrations of polyethylene glycols (PEGs), ficoll, dextran, and lysozyme using ...
Małgorzata Lobka, Joanna Trylska
wiley +1 more source
A photocontrolled RAFT strategy enables the alternating copolymerization of 1,3‐disubstituted bicyclo[1.1.0]butanes with electron‐deficient comonomers, affording well‐defined copolymers bearing strained cyclobutane backbones. A high degree of alternation, tunable molecular weights, and excellent end‐group fidelity are achieved through a CTA‐mediated ...
Xia Hu +4 more
wiley +2 more sources
Bioorthogonal Chemistry in Neurobiology: From Imaging to Proteomics
This review highlights emerging strategies for labeling neuronal proteins, enabling visualization and quantitative analysis of their expression, localization, and dynamics. By combining genetic code expansion (GCE), metabolic labeling, and click chemistry‐based labeling, these approaches provide powerful routes to study proteins in specific cells and ...
Neil Taylor +2 more
wiley +1 more source
Encoding Cell‐Surface Receptor Function Through Glycosylation: Lessons From CD44
CD44 function is not solely determined by its protein sequence, it is dynamically encoded by its glycosylation state. Glycan remodeling generates distinct functional receptor states that regulate ligand recognition, receptor organization, lectin interactions, and signaling.
María Payá‐García +7 more
wiley +1 more source
Probing macromolecular crowding at the lipid membrane interface with genetically-encoded sensors. [PDF]
Löwe M +5 more
europepmc +1 more source
ATP itself is able to undergo liquid–liquid phase separation in the presence of the macromolecular crowding agent PEG and physiological ATP concentrations are sufficient for phase separation in the presence of mM Mg2+ and crowders, mimicking intracellular conditions.
Robert Dec +2 more
wiley +1 more source
Macromolecular Crowding as a Regulator of Transcription
Inspired by PWS experiments showing cell nanostructural changes in early carcinogenesis, we developed models to study changes in transcription due to macromolecular crowding.
openaire +2 more sources
Atomic Force Microscopy Imaging of DNA under Macromolecular Crowding Conditions
Studying the influence of macromolecular crowding at high ionic strengths on assemblies of biomolecules is of particular interest because these are standard intracellular conditions. However, up to now, no techniques offer the possibility of studying the
Loïc Hamon (75173) +7 more
core +1 more source
Understanding the Impacts of Molecular and Macromolecular Crowding Agents on Protein-Polymer Complex Coacervates. [PDF]
Biswas S +5 more
europepmc +1 more source

