Results 141 to 150 of about 228,358 (272)

Hybrid Quatsome‐Encapsulated Silver Nanoparticles as Stable Plasmonic Substrates for Surface‐Enhanced Raman Scattering

Journal of Raman Spectroscopy, EarlyView.
In this work, silver nanoparticles encapsulated within quatsome membranes have shown to preserve their plasmonic properties for at least 165 days without aggregation. These hybrid nanostructures enable strong SERS enhancement of pyrene and Prodan by confining the molecules within a few nanometers from the silver surface.
Renato Cezar Peramezza Ribeiro, Caio Hiroaki Miyake, Pedro Henrique Figueiredo Backes Costa, Jhenifer Hallen Braga Mauricio, Ana Luiza Correa Januário, Diogo Soga, Evandro Luiz Duarte, Márcia de Almeida Rizzutto, Rômulo Augusto Ando, Antonio Rodrigues da Cunha, Erix Alexander Milán‐Garcés   +10 more
wiley   +1 more source

Improving Fetal Single‐Voxel Magnetic Resonance Spectroscopy With Spectral Registration

Magnetic Resonance in Medicine, EarlyView.
ABSTRACT Purpose To evaluate whether spectral registration improves spectral quality and quantification reliability in in vivo single‐voxel fetal brain MRS: Methods Fourteen fetal PRESS datasets were acquired at 3 T at TE = 35 ms and TE = 135 ms. Raw data were processed with eddy‐current phase correction, coil combination, spectral registration, and ...
Andres Saucedo, Qinqin Yang, Ali Gholipour   +2 more
wiley   +1 more source

Comparison of Calorimetry and NMR Relaxometry Measurements of Epoxy Cure Kinetics

Journal of Polymer Science, EarlyView.
Single‐sided NMR monitors epoxy cure in three DGEBA/diamine systems, alongside benchmark DSC measurements. Fitting both datasets to a Kamal‐Malkin kinetic model shows NMR‐derived rate constants typically exceed DSC values, revealing an offset between gelation and chemical conversion.
Olivia Cassara, Kayla Copeman, Sydney Joyce Tate, Jack Ballenger, Tyler Meldrum   +4 more
wiley   +1 more source

Generalizing the Gaussian Network Model: Spanning‐Tree Thermodynamics Shows Entropy‐Driven KRAS Activation

Proteins: Structure, Function, and Bioinformatics, EarlyView.
ABSTRACT The GTPase KRAS executes a conformational switch between a GTP‐bound active state and a GDP‐bound inactive state, a process central to oncogenic signaling. However, the structural basis of this switching at the level of residue‐contact organization remains incompletely characterized by traditional binary structural models.
Fatma Senguler Ciftci, Burak Erman
wiley   +1 more source

Impact of Stabilizing Osmolytes on the Conformational Dynamics of Human and Rat Islet Amyloid Polypeptides

Proteins: Structure, Function, and Bioinformatics, EarlyView.
ABSTRACT The aggregation of human islet amyloid polypeptide (hIAPP) into cytotoxic oligomers and amyloid fibrils is a hallmark of type 2 diabetes mellitus (T2DM), leading to pancreatic β‐cell dysfunction. In contrast, rat IAPP (rIAPP) is largely non‐amyloidogenic. Osmolytes such as glucose, glycerol, and sorbitol are known to stabilize globular protein
Kiara A. Kidman, Claudio Pedrick, Cara A. Kreck, Ricardo L. Mancera   +3 more
wiley   +1 more source

How does macromolecular crowding affect protein-Ligand association? A multiscale Brownian dynamics simulation approach

Riccardo Beccaria, Abraham Muñiz-Chicharro, Rebecca C. Wade   +2 more
  +4 more sources

Single and dual RPA‐CRISPR/Cas assays for point‐of‐need detection of Stewart's wilt pathogen (Pantoea stewartii subsp. stewartii) of corn and Maize dwarf mosaic virus

Pest Management Science, Volume 81, Issue 4, Page 1988-1999, April 2025.
Schematic diagram of the single and dual RPA‐CRISPR/Cas12a/13a diagnostic assays for the detection of Pantoea stewartii subsp. stewartii and Maize dwarf mosaic virus. The validated assays provide a useful and sensitive molecular tool for detecting two quarantine pathogens of maize within a minimal resource framework suitable for fast‐tracking the ...
Qian Tian, Hua Zhou, Zhenxing Zhao, Yongjiang Zhang, Wenjun Zhao, Lulu Cai, Tao Guo   +6 more
wiley   +1 more source

Topology‐Encoded Charge Polarity Governs Multiphase Organization in Intrinsically Disordered Protein Polymer Condensates

Small, EarlyView.
Electrostatic topology is shown to program phase separation and internal organization in thermoresponsive intrinsically disordered protein polymer (IDPP) condensates. By comparing oppositely charged IDPPs with a covalent diblock, chain connectivity is revealed to control charge compensation, dense‐phase micropolarity, miscibility, and apparent acid ...
Julio Fernández‐Fernández, Vicente Domínguez‐Arca, Raúl Escribano, Sheila Lorenzo, Sergio Ferrero, Sergio Acosta, José Carlos Rodríguez‐Cabello   +6 more
wiley   +1 more source

Symmetry‐Guided Optical Control of Dynamic 1D Protein Self‐Assembly and Precise In Vitro Initiation of Biomolecular Condensation

Small, EarlyView.
A photoreversible 1D protein assembly has been developed by utilizing symmetry matching between StrepTactin and photoswitchable Dronpa145N. The light‐induced modulation of oligomerization allows for precise control over protein connectivity and valency.
Jangwon Bae, Yongwon Jung
wiley   +1 more source

A lysosome‐targeted ultra‐sensitive viscosity probe for monitoring viscosity alterations during chemotherapy

Smart Molecules, EarlyView.
A novel chemosensing platform based on a molecular rotor architecture is established for specific, dynamic detection of lysosomal viscosity. The platform allows real‐time tracking of lysosomal viscosity fluctuations induced by various chemotherapeutic agents, highlighting its significant potential as a powerful tool for early cancer diagnostics and ...
Haoyang Song, Hui Bian, Lei Liu, Gahyeon Park, Bingqing Sun, Qiongzheng Hu, Juyoung Yoon   +6 more
wiley   +1 more source