Results 121 to 130 of about 103,280 (234)

PEG400 regulates Falcipain 2 activity through an allosteric mechanism

The FEBS Journal, EarlyView.
Falcipain‐2 can potentially be leveraged as a drug target due to its critical role as a haemoglobinase during the intra‐erythrocytic stage of Plasmodium falciparum. Here, we investigate the regulation of the proteolytic and haemoglobinase activity of falcipain‐2 in the presence of polyethylene glycol.
Bikram Nath, Subhoja Chakraborty, Sampa Biswas   +2 more
wiley   +1 more source

Macromolecular crowding between the natural and unnatural

Cells are densely packed with molecules of different sizes and chemistries that constantly move and interact with each other. This macromolecular crowding strongly influences how biological reactions occur, affecting processes such as diffusion ...
Kalacheva, Milara, Sub Cellular Protein Chemistry, Boersma, Arnold, Braakman, Ineke   +3 more
core  

Ribosomes as Macromolecular Crowding Sensors

Macromolecular crowding is largely understudied, and yet, may play a key role in many biological processes. The intracellular environment is packed with macromolecules of many different shapes and sizes that function and interact to maintain homeostatic ...
Ingram, Kayla S
core   +1 more source

The oral microbiota and periodontal health in orthodontic patients

Periodontology 2000, EarlyView.
Abstract The oral microbiota develops within the first 2 years of childhood and becomes distinct from the parents by 4 years‐of‐age. The oral microbiota plays an important role in the overall health/symbiosis of the individual. Deviations from the state of symbiosis leads to dysbiosis and an increased risk of pathogenicity.
Brandon W. Peterson, Geerten‐Has Tjakkes, Anne‐Marie Renkema, David J. Manton, Yijin Ren   +4 more
wiley   +1 more source

Impact of Threading State on the Mechanics of γ‐Cyclodextrin–Pyrene Gels

Angewandte Chemie, Volume 138, Issue 42, 12 October 2026.
Tuning the threading state of discrete γ‐cyclodextrin (γ‐CD)–pyrene pseudorotaxane crosslinkers controls gel topology and ring mobility. The resulting doubly threaded slide‐ring networks exhibit solvent‐switchable dissipative dynamics, high extensibility, rate‐dependent mechanics, and low hysteresis, revealing how crosslink topology governs macroscopic
Jongwon Oh, Heyi Liang, Natsumi Nitta, Jongmin Kim, Yuan Tian, Guancen Liu, Jerald E. Hertzog, Juan J. de Pablo, Stuart J. Rowan   +8 more
wiley   +2 more sources

Reviewing the benefits and clinical outcomes of oral fibroblasts over mesenchymal stem cells for repairing periodontal defects during or after orthodontic tooth movement

Periodontology 2000, EarlyView.
Abstract Orthodontic therapy applies forces to teeth, causing an inflammatory reaction in the periodontal ligament. This is repaired by remodeling of the periodontium, allowing tooth displacement. Although orthodontic therapy is mostly initiated during childhood and adolescence, the number of adults seeking this treatment is increasing as our society's
Ludovica Parisi, Eleni Mavrogonatou, Anton Sculean, Dimitris Kletsas, Martin Degen   +4 more
wiley   +1 more source

Atomic Force Microscopy Imaging of DNA under Macromolecular Crowding Conditions

, 2007
International audienceStudying the influence of macromolecular crowding at high ionic strengths on assemblies of biomolecules is of particular interest because these are standard intracellular conditions.
Curmi, Patrick, Hamon, Loic, Le Cam, Eric, PASTRE, David, Baconnais, Sonia, Piétrement, Olivier, Mechulam, Alain, Sorel, Isabelle   +7 more
core   +1 more source

Genome‐Wide Association Studies of Micro‐and Macro‐Mineral Concentrations in Cultivated, Wild and Native Pea

Legume Science, Volume 8, Issue 4, December 2026.
ABSTRACT Pea (Pisum sativum) is a nutrient‐rich crop that can provide essential nutrients needed for human and animal health. Improving its mineral concentration through genetic selection can enhance its nutritional value and help combat micronutrient deficiencies. This study aimed to investigate the genetic basis of the accumulation of eight minerals (
Maryam Bagheri, Carla S. Santos, Diego Rubiales, Osman Zakaria Wohor, Marta W. Vasconcelos   +4 more
wiley   +1 more source

Click'n ROPISA: One‐Pot Synthesis of Ultrabright Fluorescent Nanoparticles Made of Polypeptides

Angewandte Chemie, Volume 138, Issue 41, 5 October 2026.
Self‐assembly and fluorophore conjugation proceed rapidly in a one‐pot “Click'n ROPISA” process, yielding intensely fluorescent polypeptide nanoparticles with tunable visible emission. High dye loading enables efficient energy transfer and single‐particle visualization, while the straightforward synthesis provides versatile access to bright ...
Amin El Jarroudi Hammou, Juliette Lavainne, Rohit Mangalwedhekar, Jyothis Devasia, Laurent Cognet, Sébastien Lecommandoux, Colin Bonduelle, Chloé Grazon   +7 more
wiley   +2 more sources

Improving Fetal Single‐Voxel Magnetic Resonance Spectroscopy With Spectral Registration

Magnetic Resonance in Medicine, Volume 96, Issue 6, Page 2578-2587, December 2026.
ABSTRACT Purpose To evaluate whether spectral registration improves spectral quality and quantification reliability in in vivo single‐voxel fetal brain MRS: Methods Fourteen fetal PRESS datasets were acquired at 3 T at TE = 35 ms and TE = 135 ms. Raw data were processed with eddy‐current phase correction, coil combination, spectral registration, and ...
Andres Saucedo, Qinqin Yang, Ali Gholipour   +2 more
wiley   +1 more source