Results 101 to 110 of about 103,280 (234)

Residue-Level Interrogation of Macromolecular Crowding Effects on Protein Stability [PDF]

, 2008
Theory predicts that macromolecular crowding affects protein behavior, but experimental confirmation is scant. Herein, we report the first residue-level interrogation of the effects of macromolecular crowding on protein stability.
Li, Conggang, Orans, Jillian, Pielak, Gary J., Charlton, Lisa M., Barnes, Christopher O., Young, Gregory B.   +5 more
core   +1 more source

Spatiotemporal Regulation of Hierarchical Assembly of Hydroxyapatite for Enamel Remineralization

Advanced Science, EarlyView.
Biomimetic repair exhibits unique advantages for enamel regeneration compared with conventional clinical treatments. An enzymatic mineralization system (EMS) is developed, where the resulting HAP nanorods hierarchically assemble into a highly ordered structure on the enamel surface through the spatiotemporal modulation of interfacial energies of ...
Zhenhang Tang, Zhisen Zhang, Yuanyu Zhou, Wenzhi Wu, Congrui Zhao, Chang Liu, Tong Shi, Wenjing Jin, Zhaoming Liu, Weifeng Fang, Qingyun Lin, Yi He, Zhijian Xie, Ruikang Tang, Changyu Shao, Zhuo Chen   +15 more
wiley   +1 more source

Combined effects of agitation, macromolecular crowding, and interfaces on amyloidogenesis.

, 2012
Amyloid formation and accumulation is a hallmark of protein misfolding diseases and is associated with diverse pathologies including type II diabetes and Alzheimer's disease (AD).
Jean, L, Vaux, DJ, Shaw, M., Bird, S., Shaw, M, Vaux, D., Lee, CF, Bird, S, Jean, L., Lee, C.   +9 more
core   +1 more source

Single-molecule identification of the entropy/enthalpy contributions in macromolecule crowding induced by Carboxylated chitosan

Polymer Testing
Macromolecular crowding effects frequently drive phase separation and have a significant impact on a series of biochemical processes in the cell. Owing to the significant differences in the physical mechanisms of the macromolecular crowding effects ...
Xiaogang Zhu, Shijian Chen, Yuyu Feng, Rongri Tan, Junhua Yuan, Hu Chen, Yanhui Liu   +6 more
doaj   +1 more source

Polymer Concepts in Cellular Function

Advanced Science, EarlyView.
Miao Yu, Shikha Dhiman, Dorothee Dormann, Frauke Gräter, Katja Luck, Friederike Schmid, Andreas Walther, Edward A. Lemke   +7 more
wiley   +1 more source

Integrating One Health to Mitigate the Emergence and Spread of Antimicrobial Resistance in Livestock and Aquaculture

Animal Research and One Health, EarlyView.
Antimicrobial resistance (AMR) is an escalating global threat driven by antimicrobial use in aquaculture and livestock. Resistant pathogens and genes can spread across humans, animals, and the environment through interconnected ecosystems. Using a One Health approach, this review emphasizes antimicrobial stewardship, regulatory strengthening, enhanced ...
Mir Mohammad Ali, Delower Hossain, Ridwan Olamilekan Adesola, Anum Hanif, Shamsaldeen Ibrahim Saeed, Muhammad Abdul Mannan, Anoar Jamai Masroure, Kazi Estieque Alam, Md Kamal Hossain, Sabiha Zarin Tasnim Bristi, Md Jisan Ahmed   +10 more
wiley   +1 more source

Biochemical Studies and Production Optimization of β‐Glucosidase From Microcystis aeruginosa CACIAM 03 Using Organic Waste

Biotechnology and Applied Biochemistry, EarlyView.
ABSTRACT Global warming and industrial pollutants pose significant threats to environmental sustainability. In response, enzymes have emerged as promising tools for mitigating pollution. Enzymatic hydrolysis is considered environmentally sustainable due to its biological nature.
Gustavo Marques Serra, Matheus Silva da Fonseca Diniz, Evonnildo Costa Gonçalves, Agenor Valadares Santos, Luciana Pereira Xavier   +4 more
wiley   +1 more source

Artificial Cell Catalysts for Biotransformation: Design Principles and Process Integration

Biotechnology and Bioengineering, EarlyView.
ABSTRACT Artificial cell catalysts are emerging as programmable biocatalytic platforms for sustainable molecular conversion. By reconstituting enzymes and functional modules within synthetic compartments, they combine the selectivity of biological catalysis with the design flexibility of synthetic materials.
Iori Kobayashi, Shogo Yoshimoto, Katsutoshi Hori   +2 more
wiley   +1 more source

Macromolecular crowding [PDF]

Current Biology, 2006
openaire   +3 more sources

Long Fluorescence Lifetime Molecular Rotors Based on the 4,4‐Dicyano‐BODIPY Core

Chemistry – A European Journal, EarlyView.
Substituting fluorine with cyano groups in BODIPY‐based fluorescent molecular rotors yields viscosity‐sensitive dyes with significantly enhanced fluorescence lifetimes that can be used for viscosity mapping in living cells using FLIM microscopy. ABSTRACT Environmentally sensitive fluorescent probes with extended emission lifetimes are highly valuable ...
Yelyzaveta Denysieva, Ludovic Richert, Yves Mély, Julie Karpenko, Dmytro Dziuba   +4 more
wiley   +1 more source