Results 101 to 110 of about 6,829 (247)
An Equilibrium Model for the Combined Effect of Macromolecular Crowding and Surface Adsorption on the Formation of Linear Protein Fibrils [PDF]
, 2015 Travis Hoppe, Allen P. Minton
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Proteins: Structure, Function, and Bioinformatics, EarlyView.ABSTRACT The aggregation of human islet amyloid polypeptide (hIAPP) into cytotoxic oligomers and amyloid fibrils is a hallmark of type 2 diabetes mellitus (T2DM), leading to pancreatic β‐cell dysfunction. In contrast, rat IAPP (rIAPP) is largely non‐amyloidogenic. Osmolytes such as glucose, glycerol, and sorbitol are known to stabilize globular protein
Kiara A. Kidman +3 more
wiley +1 more source
Pest Management Science, Volume 81, Issue 4, Page 1988-1999, April 2025.Schematic diagram of the single and dual RPA‐CRISPR/Cas12a/13a diagnostic assays for the detection of Pantoea stewartii subsp. stewartii and Maize dwarf mosaic virus. The validated assays provide a useful and sensitive molecular tool for detecting two quarantine pathogens of maize within a minimal resource framework suitable for fast‐tracking the ...
Qian Tian +6 more
wiley +1 more source
Atomistic Simulations of Macromolecular Crowding [PDF]
Biophysical Journal, 2010 Protein folding, binding, and aggregation are known to be affected by macromolecular crowding [1], which is an integral part of intracellular environments. Realistic modeling of intracellular crowding requires computer simulations. In direct simulations of test proteins mixed with crowders, it has only been practical to represent the proteins at a ...
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Effects of macromolecular crowding on protein folding [PDF]
, 2015 Bui Phuong Thuy +2 more
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Macromolecular crowding modulates α-synuclein amyloid fiber growth [PDF]
, 2021 István Horváth +2 more
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BODIPY Photocage‐Based Injectable Hydrogel for Light‐Controlled Nanoparticle Release
Small, EarlyView.This work presents an injectable hydrogel formulation which undergoes efficient photodegradation under green light irradiation. The gel can be easily injected to subcutaneous tissue through 23G needles, co‐encapsulate and photo‐release nanoparticles as well as exhibits excellent biocompatibility, making it promising for the development of light ...
Baihao Shao +8 more
wiley +1 more source
Nature Communications, 2017 Crowding effects—important when considering cellular environments—greatly influence protein stability. Here the authors study the impact of macromolecular crowders on high and low temperature protein unfolding, and show that volume exclusion effects are ...
Caterina Alfano +4 more
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A Tale of Two Dimers: GFP Proteins under Macromolecular Crowding Studied by Small Angle Neutron Scattering [PDF]
, 2012 Shuo Qian +4 more
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Porous Organic Polymers: From Molecular Design to Scalable Technologies
Small, EarlyView.This review introduces porous organic polymers (POPs) for a wide range of applications, including energy storage, gas adsorption, catalysts, adsorbents, biomedical applications, sensors, and other exciting fields, and critically analyzes the synthesis and modification, and how structural topology influences the composites' architecture of POPs, along ...
Hossein Mashhadimoslem +12 more
wiley +1 more source