Results 91 to 100 of about 228,358 (272)
Scientific Reports, 2021 Macromolecular crowding (MMC) in cells is a hot topic in biology; therefore, well-characterized measurement standards for the evaluation of the nano-environment in MMC solutions are necessary.
Johtaro Yamamoto +7 more
semanticscholar +1 more source
Advanced Healthcare Materials, EarlyView.Mitochondria‐targeted nanotherapies emerge as a promising strategy for combating aging‐associated neurodegenerative disorders (NDs) by restoring mitochondrial function, reducing oxidative stress, and improving neuronal survival. Recent advances in nanotechnology, therapeutic delivery, and translational research are highlighted, providing insights into ...
Dnyandev G. Gadhave +8 more
wiley +1 more source
Seaweed polysaccharides as macromolecular crowding agents
International Journal of Biological Macromolecules, 2020 Development of mesenchymal stem cell-based tissue engineered implantable devices requires prolonged in vitro culture for the development of a three-dimensional implantable device, which leads to phenotypic drift, thus hindering the clinical translation and commercialisation of such approaches.
De Pieri, Andrea +3 more
openaire +3 more sources
Macromolecular crowding as a suppressor of human IAPP fibril formation and cytotoxicity. [PDF]
PLoS ONE, 2013 The biological cell is known to exhibit a highly crowded milieu, which significantly influences protein aggregation and association processes. As several cell degenerative diseases are related to the self-association and fibrillation of amyloidogenic ...
Janine Seeliger +2 more
doaj +1 more source
Advanced Materials, EarlyView.Azobenzene photoswitches translate molecular‐scale E/Z photoisomerization into macroscopic material responses and device‐level photonic functions. This Review highlights how azobenzene research has evolved from molecular photochemistry to photoalignment, mass migration, photomechanics, and heat release, ultimately enabling holography, reconfigurable ...
Heeju Son +20 more
wiley +1 more source
How does domain replacement affect fibril formation of the rabbit/human prion proteins. [PDF]
PLoS ONE, 2014 It is known that in vivo human prion protein (PrP) have the tendency to form fibril deposits and are associated with infectious fatal prion diseases, while the rabbit PrP does not readily form fibrils and is unlikely to cause prion diseases.
Xu Yan +4 more
doaj +1 more source
Macromolecular crowding facilitates rapid fabrication of intact, robust cell sheets
Biotechnology Letters, 2022 Objectives To develop a rapid and simple method to fabricate intact, robust cell sheets from common cell culture dishes by combination of a macromolecular crowding (MMC) reagent and vitamin C.
Shuwen Guan +4 more
semanticscholar +1 more source
Advanced Materials, EarlyView.Cancer‐associated NPC remodeling creates a high‐flux, low‐stringency nuclear state that supports malignant adaptation but increases mechanical fragility. Targeting the FG‐barrier or NPC scaffold may drive mechanostat failure, envelope rupture, DNA damage, and loss of nuclear integrity.
Sílvio Terra Stefanello +5 more
wiley +1 more source
Frontiers in Physics, 2018 Macromolecular crowding plays a principal role in a wide range of biological processes including gene expression, chromosomal compaction, and viral infection.
Warren M. Mardoum +4 more
doaj +1 more source
All‐Amyloid Functional Coacervates
Advanced Materials, EarlyView.This study introduces an all‐amyloid interfacial complex coacervate technique that employs charge‐mediated or functionalization‐assisted complexation of oppositely charged food protein‐derived amyloid nanofibrils to engineer functional soft constructs across multiple length scales.
Seyyed Alireza Hashemi +4 more
wiley +1 more source