Solvatochromic Properties of Acdan and Spectral Phasor Analysis Reveal the Role of Aquaporin 0A in Regulating Macromolecular Crowding in the Zebrafish Lens In Vivo [PDF]
, 2020 Leonel Malacrida +6 more
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Residue‐level mapping of crowding effects on protein phase separation
Protein Science, Volume 35, Issue 4, April 2026.Abstract Protein liquid–liquid phase separation has emerged as a key mechanism in cellular organization. While the crowded environment inside cells is expected to influence this process, how crowding shapes the chemical environment and impacts protein phase separation remains largely unknown.
Wei Chen +3 more
wiley +1 more source
Insights into the disparate action of osmolytes and macromolecular crowders on amyloid formation [PDF]
, 2012 Shahar Sukenik, Daniel Harries
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Structural Modeling and Dynamics of the Full‐Length Homer1 Multimer
Proteins: Structure, Function, and Bioinformatics, Volume 94, Issue 4, Page 947-960, April 2026.ABSTRACT Homer proteins are modular scaffold molecules that constitute an integral part of the protein network within the postsynaptic density. Full‐length Homer1 forms a large homotetramer via a long coiled coil region, and can interact with proline‐rich target sequences with its globular EVH1 domain.
Zsófia E. Kálmán +9 more
wiley +1 more source
Macromolecular Crowding and DNA: Bridging the Gap between In Vitro and In Vivo. [PDF]
Int J Mol Sci, 2023 Collette D, Dunlap D, Finzi L.
europepmc +1 more source
Macromolecular Crowding Induces a Molten Globule State in the C-Terminal Domain of Histone H1 [PDF]
, 2007 Alicia Roque, Inma Ponte, Pedro Suau
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Probing macromolecular crowding at the lipid membrane interface with genetically-encoded sensors. [PDF]
Protein Sci, 2023 Löwe M +5 more
europepmc +1 more source
ChemBioChem, Volume 27, Issue 5, 13 March 2026.This review examines the structural and enzymatic properties of cyclic GMP‐AMP synthase, including substrate promiscuity, homologs, and engineered variants. In addition, it evaluates potential expression systems for large‐scale enzyme production and analyzes reaction and purification strategies for the synthesis of cyclic dinucleotides to connect ...
Makram Fataeri, Katrin Rosenthal
wiley +1 more source
Role of tau in the spatial organization of axonal microtubules: keeping parallel microtubules evenly distributed despite macromolecular crowding [PDF]
, 2016 Alix Méphon-Gaspard +7 more
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