Results 191 to 200 of about 103,280 (234)

Development of Biomimetic Substrates for Limbal Epithelial Stem Cells Using Collagen-Based Films, Hyaluronic Acid, Immortalized Cells, and Macromolecular Crowding. [PDF]

Life (Basel)
Gurdal M, Ercan G, Barut Selver O, Aberdam D, Zeugolis DI.   +4 more
europepmc   +1 more source

The influence of crowding on macromolecular compactness

Seibutsu Butsuri, 2001
N Tokuriki, M Kinjo, K Ogasawara, K Yutani, M Kataoka, I Urabe, T Yomo   +6 more
openaire   +2 more sources

Carrageenan maintains the contractile phenotype of vascular smooth muscle cells by increasing macromolecular crowding in vitro. [PDF]

Eur J Med Res
Liu Q, Jiang HJ, Wu YD, Li JD, Sun XH, Xiao C, Xu JY, Lin ZY.   +7 more
europepmc   +1 more source

An easy-to-use microfluidic mechano-chemostat for tissues and organisms reveals that confined growth is accompanied with increased macromolecular crowding

, 2023
Meriem ZB, Mateo T, Faccini J, Denais C, Dusfour-Castan R, Guynet C, Merle T, Suzanne M, Di-Luoffo M, Guillermet-Guibert J, Alric B, Landiech S, Malaquin L, Mesnilgrente F, Laborde A, Mazenq L, Courson R, Delarue M.   +17 more
europepmc   +1 more source

Corrigendum to "In vitro and in vivo assessment of a non-animal sourced chitosan scaffold loaded with xeno-free umbilical cord mesenchymal stromal cells cultured under macromolecular crowding conditions" [Biomaterials and Biosystems, Volume 16, December 2024, 100102]. [PDF]

Biomater Biosyst
Nubila AD, Doulgkeroglou MN, Gurdal M, Korntner SH, Zeugolis DI.   +4 more
europepmc   +1 more source

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Macromolecular crowding: obvious but underappreciated

Trends in Biochemical Sciences, 2001
Biological macromolecules evolve and function within intracellular environments that are crowded with other macromolecules. Crowding results in surprisingly large quantitative effects on both the rates and the equilibria of interactions involving macromolecules, but such interactions are commonly studied outside the cell in uncrowded buffers.
R J Ellis, R John Ellis
exaly   +3 more sources

Liposome-Encapsulated Escherichia coli Lysates to Reconstitute Intracellular Macromolecular Crowding Effects [PDF]

ACS Synthetic Biology
Intracellular macromolecular crowding impacts biomacromolecule behavior, including oligomerization, phase separation, and diffusion. However, understanding crowding effects in cells is challenging as cells respond and adapt to perturbations.
Arnold J. Boersma, Nuno R da Silva
exaly   +3 more sources

Macromolecular dynamics in crowded environments

The Journal of Chemical Physics, 2010
The structural and dynamical properties of macromolecules in confining or crowded environments are different from those in simple bulk liquids. In this paper, both the conformational and diffusional dynamics of globular polymers are studied in solutions containing fixed spherical obstacles.
Carlos, Echeverria, Raymond, Kapral
openaire   +2 more sources

Macromolecular Crowding and Protein Stability

Journal of the American Chemical Society, 2012
An understanding of cellular chemistry requires knowledge of how crowded environments affect proteins. The influence of crowding on protein stability arises from two phenomena, hard-core repulsions and soft (i.e., chemical) interactions. Most efforts to understand crowding effects on protein stability, however, focus on hard-core repulsions, which are ...
Yaqiang, Wang, Mohona, Sarkar, Austin E, Smith, Alexander S, Krois, Gary J, Pielak   +4 more
openaire   +2 more sources

Macromolecular Crowding and Its Consequences

1999
Incompatible pairs of polymers separate into two phases in aqueous solution above a few percentage points total concentration. Protein pairs can also produce phase separation, but at somewhat higher concentrations. In this chapter, we explore the effect of high background concentrations of macromolecules on phase separation of pairs of species which ...
H O, Johansson, D E, Brooks, C A, Haynes
openaire   +2 more sources