Results 141 to 150 of about 546,176 (246)

Biointerface Membranes Orchestrating Site‐Specific Osteoimmunomodulatory and Antibacterial Effects for Enhanced Osseous Regeneration in Periodontal Therapy

Advanced Functional Materials, EarlyView.
Here, a biointerface membrane engineered with site‐specific interfacial properties is developed. During implantation between gingival and bone defect, the membrane creates a pro‐osteogenic microenvironment, precisely modulates cellular activities at each biointerface, and facilitates the orchestration of complex healing events, ultimately leading to ...
Yuwei Zhu, Tingting Wang, Jing Zhu, Bingtian Zhao, Bingyang Dai, Xiaoyue Zhang, Wei Liu, Cheng Yang, Cheng Dong, Ren Liu, Lei Zhao, Jun Wang, Peilei Shi, To Ngai   +13 more
wiley   +1 more source

Single-Cell Analyses Reveal IKKα Regulates the Interaction Between Macrophages and T Cells in the Doxorubicin-Induced Cardiomyopathy. [PDF]

Inflammation
Chen G, Yao Y, Jiang Y, Qi H, Liu Y, Yin L, Li J, Cao Y, Chen X, Zhu Y, Liu S, Tao Z.   +11 more
europepmc   +1 more source

Novel Functional Materials via 3D Printing by Vat Photopolymerization

Advanced Functional Materials, EarlyView.
This Perspective systematically analyzes strategies for incorporating functionalities into 3D‐printed materials via Vat Photopolymerization (VP). It explores the spectrum of achievable functionalities in recently reported novel materials—such as conductive, energy‐storing, biodegradable, stimuli‐responsive, self‐healing, shape‐memory, biomaterials, and
Sergey S. Nechausov, Patrick Fesser, Boris A. Bulgakov, Ulrich S. Schubert   +3 more
wiley   +1 more source

Monocyte chemoattractant protein-1 from a conditioned medium of bone marrow-derived mesenchymal stem cells promotes bone regeneration by enhancing macrophage phenotype polarization. [PDF]

Maxillofac Plast Reconstr Surg
Hashizume K, Katagiri W, Takeuchi R, Suda D, Kobayashi T.   +4 more
europepmc   +1 more source

Self‐Powered Permeable Electronic Dressing for Exudate Management, Electrostimulation and Drug Delivery in Chronic Wound Healing

Advanced Functional Materials, EarlyView.
This study develops a self‐powered permeable electronic dressing (SPED) that synergistically integrates exudate management, electrical stimulation, and on‐demand drug delivery. The dressing effectively absorbs exudate while demonstrating potent antibacterial activity and accelerated tissue regeneration in diabetic mouse models, thereby promoting ...
Jiaheng Liang, Jingjing Fu, Jin Chai, Hongyu Jiang, Fan Chen, Yufei Zhang, Weihao Zhao, Xian Song, Zhihao Zhou, Lingtao Fang, Qiyao Huang, Peng Li, Zijian Zheng   +12 more
wiley   +1 more source

Enhancing Cancer Vaccine Efficacy: Backbone Modification with β‑Amino Acids Alters the Stability and Immunogenicity of MUC1-Derived Glycopeptide Formulations

JACS Au
Ruslan Gibadullin, Óscar Suárez, Foivos S. Lazaris, Naiara Gutiez, Estibaliz Atondo, Sarai Araujo-Aris, Ander Eguskiza, Jiani Niu, Ariel J. Kuhn, Ana S. Grosso, Héctor Rodriguez, Fayna García-Martín, Filipa Marcelo, Tanausú Santos, Alberto Avenoza, Jesús H. Busto, Jesús M. Peregrina, Samuel H. Gellman, Juan Anguita, Roberto Fiammengo, Francisco Corzana   +20 more
doaj   +1 more source

Polarization-Specific Macrophage-Derived Extracellular Vesicles: Molecular Cargo, Tumor Microenvironment Remodeling, and Therapeutic Opportunities. [PDF]

Int J Nanomedicine
Liu X, Yang Y, Ren L.
europepmc   +1 more source

Poly(lactic‐co‐glycolic acid) Nanoparticles for IL‐12 Self‐Amplifying RNA Delivery in Glioblastoma Models

Advanced Functional Materials, EarlyView.
xxxx. ABSTRACT Glioblastoma (GBM) remains one of the most lethal brain cancers, with median survival rarely exceeding 15 months after diagnosis. Interleukin‐12 (IL‐12) is a potent immunostimulatory cytokine capable of reshaping the tumor microenvironment (TME), yet its clinical translation is hindered by systemic toxicity and short half‐life. RNA‐based
Fatima Hameedat, Johan Sebastian Lopez‐Parra, Willem M. H. Hoogaars, Emma Dijkstra, Cynthia Huang, Irafasha C. Casmil, Anna K. Blakney, Peter Olinga, Barbara Rothen‐Rutishauser, Hélder A. Santos, Alke Petri‐Fink, Flávia Sousa   +11 more
wiley   +1 more source

Slc7a11-Mediated Cystine/Glutamate Antiport Reprograms Macrophage Polarization and Ameliorates Atherosclerosis. [PDF]

MedComm (2020)
Zhou S, Luo Y, Luo J, Li S, Liu B, Shao W, Tao J, Qi J, Fan C, Shi J, An P, Wang H, Wang F.   +12 more
europepmc   +1 more source

Laser Engineering of HfN‐Based Nanoparticles for Safe NIR‐I Photothermal and X‐ray Enhancing Cancer Therapies

Advanced Functional Materials, EarlyView.
In this study, we produced HfN‐based nanoparticles via femtosecond laser ablation in acetone. The nanoparticles exhibit a red‐shifted plasmonic resonance in the NIR‐I window, colloidal stability after coating with polyethyleneglycol, and excellent biocompatibility. The photothermal and X‐ray sensitization therapeutic effects were demonstrated for tumor
Julia S. Babkova, Ivan V. Zelepukin, Lyubov V. Gorelik, Anton L. Popov, Andrei I. Pastukhov, Gleb V. Tikhonowski, Maxim S. Savinov, Danil D. Kolmanovich, Nikita A. Pivovarov, Alina Yu. Kapitannikova, Anton A. Popov, Anna S. Sogomonyan, Vsevolod A. Skribitsky, Aziz B. Mirkasymov, Andrei V. Kabashin, Sergey M. Deyev   +15 more
wiley   +1 more source