Results 151 to 160 of about 1,143,350 (343)

In‐Depth Profiling Highlights the Effect of Efgartigimod on Peripheral Innate and Adaptive Immune Cells in Myasthenia Gravis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Myasthenia gravis (MG) is an autoimmune disorder characterized by antibody‐mediated complement activation. Efgartigimod, a neonatal Fc receptor (FcRn) antagonist, is approved for treating generalized MG (gMG). However, its modulatory effects on upstream innate and adaptive immune cells remain largely unexplored.
Lei Jin, Liu Dong, Ying Wang, Dingxian He, Chong Yan, Jianying Xi, Haoqin Jiang, Yu Shi, Ming Guan, Chongbo Zhao, Jie Song, Sushan Luo   +11 more
wiley   +1 more source

Ovaries of estrogen receptor 1-deficient mice show iron overload and signs of aging

Frontiers in Endocrinology
IntroductionEstrogens are crucial regulators of ovarian function, mediating their signaling through binding to estrogen receptors. The disruption of the estrogen receptor 1 (Esr1) provokes infertility associated with a hemorrhagic, cystic phenotype ...
Sarah K. Schröder, Marinela Krizanac, Philipp Kim, Jan C. Kessel, Ralf Weiskirchen   +4 more
doaj   +1 more source

Alcohol impairs J774.16 macrophage-like cell antimicrobial functions inAcinetobacter baumanniiinfection [PDF]

, 2013
Melissa B. Asplund, Carolina Coelho, Radamés J. B. Cordero, Luis R. Martinez   +3 more
openalex   +1 more source

Variably Protease‐Sensitive Prionopathy: Two New Cases With Motor Neuron‐Dementia Syndrome

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT We describe two patients with variably protease‐sensitive prionopathy (VPSPr) who developed progressive upper motor neuron symptoms, insomnia, behavioral and cognitive decline, compatible with primary lateral sclerosis associated with frontotemporal dementia (FTD).
María Elena Erro, María Victoria Zelaya, Hasier Eraña, Javier Sánchez Ruiz de Gordoa, Fermín García‐Amigot, Anika Simonovska‐Serra, María Cristina Caballero, Isidre Ferrer, Ellen Gelpi, Ivonne Jericó, Joaquín Castilla   +10 more
wiley   +1 more source

Evidence of collective influence in innate sensing using fluidic force microscopy

Frontiers in Immunology
The innate immune system initiates early response to infection by sensing molecular patterns of infection through pattern-recognition receptors (PRRs).
Elizabeth J. Mulder, Brittany Moser, Jennifer Delgado, Rachel C. Steinhardt, Aaron P. Esser-Kahn   +4 more
doaj   +1 more source

Tumour-associated macrophages exhibit anti-tumoural properties in Sonic Hedgehog medulloblastoma

, 2019
Victor Maximov, Zhihong Chen, Yun Wei, M. Hope Robinson, Cameron J. Herting, Nithya Shanmugam, Vasilisa A. Rudneva, Kelly C. Goldsmith, Tobey J. MacDonald, Paul A. Northcott, Dolores Hambardzumyan, Anna Marie Kenney   +11 more
openalex   +1 more source

“Atypical” macrophages [PDF]

Blood, 2015
Jonathan, Bloch, Sabine, Blum
openaire   +2 more sources

Patterns of Postictal Abnormalities in Relation to Status Epilepticus in Adults

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Abnormalities on peri‐ictal diffusion‐weighted magnetic resonance imaging (DWI‐PMAs) are well‐established for patients with status epilepticus (SE), but knowledge on patterns of DWI‐PMAs and their prognostic impact is sparse. Methods This systematic review and individual participant data meta‐analysis included observational studies ...
Andrea Enerstad Bolle, Silvana Sarria‐Estrada, Thomas Bonduelle, Bertram Daniel Dynesen, Manuel Toledo, Zhu Chung Che, Kjell Heuser, Anastasios Chatzikonstantinou, Jérôme Aupy, Udaya Seneviratne, Estevo Santamarina Perez, Christoph Patrick Beier   +11 more
wiley   +1 more source

SARS-CoV-2 Spike Protein Stimulates Macropinocytosis in Murine and Human Macrophages via PKC-NADPH Oxidase Signaling

Antioxidants
Coronavirus disease 2019 (COVID-19) is an infectious disease caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). While recent studies have demonstrated that SARS-CoV-2 may enter kidney and colon epithelial cells by inducing receptor ...
WonMo Ahn, Faith N. Burnett, Ajay Pandey, Pushpankur Ghoshal, Bhupesh Singla, Abigayle B. Simon, Cassandra C. Derella, Stephen A. Addo, Ryan A. Harris, Rudolf Lucas, Gábor Csányi   +10 more
doaj   +1 more source

Tracking Monocyte Recruitment and Macrophage Accumulation in Atherosclerotic Plaque Progression Using a Novel hCD68GFP/ApoE ^−/− Reporter Mouse—Brief Report [PDF]

, 2016
Eileen McNeill, Asif Iqbal, Daniel Jones, Jyoti Patel, Patricia Coutinho, Lewis Taylor, David R. Greaves, Keith M. Channon   +7 more
openalex   +1 more source