Results 41 to 50 of about 793,649 (316)
Nature Reviews Immunology, 2016 Macrophages expressing PPARγ support skeletal muscle regeneration by inducing secretion of the myoblast growth factor GDF3.
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npj Vaccines, 2021 Mycobacterium avium subsp. paratuberculosis (Map) causes paratuberculosis (PTB), a granulomatous enteritis in ruminants that exerts high economic impact on the dairy industry worldwide.
Iraia Ladero-Auñon +10 more
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Modulation of Wnt/β-catenin signaling in IL-17A-mediated macrophage polarization of RAW264.7 cells [PDF]
Brazilian Journal of Medical and Biological Research, 2020 Macrophages play pivotal roles in host defense and immune homeostasis, which have two major functional polarization states, the classically activated M1 and the alternatively activated M2.
Chao Yuan +6 more
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Rapamycin but not FK506 inhibits the proliferation of mononuclear phagocytes induced by colony-stimulating factors [PDF]
, 1994 FK506, CsA, and rapamycin are potent inhibitors of T lymphocyte activation; relatively little is known of their effects on cells of the monocyte/macrophage lineage.
Cooper, MH +3 more
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BMC Immunology, 2021 Background Differential polarization of macrophage into M1 and M2 mediates atherosclerotic plaque clearance through efferocytosis. Higher expression of Mer proto-oncogene tyrosine kinase (MerTK) on M2 macrophage helps in maintaining macrophage ...
Fatin Najiah Mohd Idrus +8 more
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A Lipid-Structured Model of Atherosclerotic Plaque Macrophages with Lipid-Dependent Kinetics [PDF]
arXiv, 2022 Atherosclerotic plaques are fatty growths in artery walls that cause heart attacks and strokes. Plaque formation is orchestrated by macrophages that are recruited to the artery wall to consume and remove blood-derived lipids, such as low-density lipoprotein (LDL).
arxiv
The pulmonary macrophage. [PDF]
Environmental Health Perspectives, 1976 An overview of the pulmonary macrophage is provided, with particular emphasis on the origin of this cell and the adaptive mechanisms whereby the macrophagic system is able to respond to increased inhalant loads of organic and inorganic pollutants. Evidence is presented which favors an hematopoietic origin for the alveolar macrophage with a monocytic ...
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Macrophage autophagy in atherosclerosis [PDF]
, 2013 Macrophages play crucial roles in atherosclerotic immune responses. Recent investigation into macrophage autophagy (AP) in atherosclerosis has demonstrated a novel pathway through which these cells contribute to vascular inflammation.
Carnuccio, R. +5 more
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Computational Approach to Identifying Universal Macrophage Biomarkers. [PDF]
, 2020 Macrophages engulf and digest microbes, cellular debris, and various disease-associated cells throughout the body. Understanding the dynamics of macrophage gene expression is crucial for studying human diseases. As both bulk RNAseq and single cell RNAseq
Dang, Dharanidhar +5 more
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Cellular Immunology, 2018 Obesity is a worldwide public health concern yet no safe therapies are currently available. The activity of sympathetic neurons is necessary and sufficient for fat mass reduction, via norepinephrine (NE) signaling. Macrophage accumulation in the adipose tissue is thought to play the central role in the onset of obesity, yet their relation to NE has ...
Ana Domingos +3 more
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