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Macrophage Activation Syndrome [PDF]
Macrophage activation syndrome (MAS) is a potentially life-threatening complication of rheumatic diseases such as systemic juvenile idiopathic arthritis (sJIA) and systemic lupus erythematosus.
Clarke, Sarah L N +2 more
core +9 more sources
Macrophage activation syndrome and COVID-19 [PDF]
An emerging, rapidly spreading coronavirus SARS-CoV-2 is causing a devastating pandemic. As we have not developed curative medicine and effective vaccine, the end of this life-threatening infectious disease is still unclear.
Ryo Otsuka, Ken-ichiro Seino
doaj +4 more sources
The Immunology of Macrophage Activation Syndrome [PDF]
Synonymous with secondary hemophagocytic lymphohistiocytosis, macrophage activation syndrome (MAS) is a term used by rheumatologists to describe a potentially life-threatening complication of systemic inflammatory disorders, most commonly systemic ...
Courtney B. Crayne +3 more
doaj +3 more sources
Macrophage activation syndrome: I/II
Abstract Macrophage activation syndrome (MAS) is a potentially fatal systemic disorder which results from uncontrolled activation and proliferation of T cells and excessive activation of macrophages. It is a distinct clinicopathologic entity that occurs in different haemophagocytic syndromes (HSs).
J Kotwal, K Shanmuganandan
doaj +2 more sources
Macrophage Activation Syndrome
Macrophage activation syndrome (MAS) is an infrequent but potentially life-threatening complication of various autoimmune diseases. It is characterized by excessive activation of macrophages induced by a dysfunction of the immune system, although the underlying abnormalities remain to be delineated.
Nidhi, Aggarwal, Rohit, Aggarwal
+8 more sources
Macrophage activation syndrome
Abstract Macrophage activation syndrome (MAS) is a serious, potentially life-threatening complication of rheumatic disorders, which is seen most commonly in systemic juvenile idiopathic arthritis (sJIA). It is characterised clinically by unremitting high fever, pancytopaenia, hepatosplenomegaly, hepatic dysfunction, encephalopathy, coagulation ...
Bianca Lattanzi +7 more
openalex +2 more sources
Background Macrophage activation syndrome is classified as a secondary form of hemophagocytic lymphohistiocytosis. It is a hyperinflammatory complication observed to be comorbid with a variety of autoimmune diseases, including adult-onset Still’s disease
Wesam Gouda +5 more
doaj +1 more source
Macrophage activation syndrome in COVID-19
The novel coronavirus epidemic is characterized by high rates of morbidity and relatively high mortality. Laboratory test results in patients include leukopenia, an increase in liver function tests and ferritin levels reaching hundreds, and sometimes ...
K. N. Grigorieva +11 more
doaj +1 more source
Cytokine release syndrome in COVID-19 patients, a new scenario for an old concern. The fragile balance between infections and autoimmunity [PDF]
On 7 January 2020, researchers isolated and sequenced in China from patients with severe pneumonitis a novel coronavirus, then called SARS-CoV-2, which rapidly spread worldwide, becoming a global health emergency.
Diamanti, A. P. +4 more
core +2 more sources
Macrophage Activation Syndrome.
Macrophage Activation Syndrome (MAS) occurs as a severe life-threatening complication of several chronic rheumatic diseases. It is more frequent with systemic onset juvenile arthritis and adult onset Still's disease.1 It can be primary, infection related, malignancy associated or autoimmune3.
P Babu, Raj +3 more
+5 more sources

