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Macrophage activation syndrome complicating early course of adult-onset Still’s disease [PDF]
Introduction. Adult-onset Still’s disease is a rare inflammatory disorder of unknown etiology. It can be complicated by macrophage activation syndrome, a potentially life-threatening condition. While macrophage activation syndrome and adult-onset Still’s
Božić Ksenija +2 more
doaj +1 more source
Macrophage Activation Syndrome in a Patient with Systemic Lupus Erythematous Triggered by Tuberculous Meningitis. [PDF]
Alowais N +5 more
europepmc +2 more sources
Macrophage Activation Syndrome
Macrophage activation syndrome (MAS) is an infrequent but potentially life-threatening complication of various autoimmune diseases. It is characterized by excessive activation of macrophages induced by a dysfunction of the immune system, although the underlying abnormalities remain to be delineated.
Nidhi, Aggarwal, Rohit, Aggarwal
+8 more sources
mTORC1 links pathology in experimental models of Still’s disease and macrophage activation syndrome
Still’s disease is an inflammatory syndrome linked to the development of further immune dysregulation and hypercytokinaemia termed macrophage activation syndrome.
Zhengping Huang +30 more
doaj +1 more source
Background Macrophage activation syndrome is classified as a secondary form of hemophagocytic lymphohistiocytosis. It is a hyperinflammatory complication observed to be comorbid with a variety of autoimmune diseases, including adult-onset Still’s disease
Wesam Gouda +5 more
doaj +1 more source
Macrophage activation syndrome in COVID-19
The novel coronavirus epidemic is characterized by high rates of morbidity and relatively high mortality. Laboratory test results in patients include leukopenia, an increase in liver function tests and ferritin levels reaching hundreds, and sometimes ...
K. N. Grigorieva +11 more
doaj +1 more source
Cytokine release syndrome in COVID-19 patients, a new scenario for an old concern. The fragile balance between infections and autoimmunity [PDF]
On 7 January 2020, researchers isolated and sequenced in China from patients with severe pneumonitis a novel coronavirus, then called SARS-CoV-2, which rapidly spread worldwide, becoming a global health emergency.
Diamanti, A. P. +4 more
core +2 more sources
Macrophage Activation Syndrome in Children: Diagnosis and Management [PDF]
Macrophage activation syndrome is a severe yet under-recognized complication encountered in pediatric rheumatology. It manifests as secondary hemophagocytic lymphohistiocytosis leading to a hyper-inflammatory state resulting from an underlying cytokine storm. If unchecked, it may lead to multiorgan failure and mortality.
Bagri, Narendra Kumar +3 more
openaire +3 more sources
Adult-onset Still’s disease with secondary macrophage activation syndrome: a case report
We describe a case of adult-onset Still’s disease (AOSD) with secondary macrophage activation syndrome. AOSD is a rare disease with unknown origin. Rarely it’s complicated by secondary macrophage activation syndrome, which is a life-threatening disorder.
Giuseppe Nicoletti +7 more
doaj +1 more source

