Results 61 to 70 of about 260,356 (192)

Elevated cerebral spinal fluid biomarkers in children with mucopolysaccharidosis I-H. [PDF]

, 2016
Mucopolysaccharidosis (MPS) type-IH is a lysosomal storage disease that results from mutations in the IDUA gene causing the accumulation of glycosaminoglycans (GAGs).
Dickson, Patricia I, Lund, Troy C, Miller, Weston P, Orchard, Paul J, Pasquali, Marzia, Polgreen, Lynda E, Raymond, Gerald V   +6 more
core   +1 more source

Macrophage activation syndrome with acute hepatitis in a patient with adult-onset immunodeficiency with anti-interferon gamma antibodies: a case report

Journal of Medical Case Reports
Background Macrophage activation syndrome is a rare disorder leading to unregulated immune activity manifesting with nonspecific constitutional symptoms, laboratory abnormalities, and multiorgan involvement.
William Hirsch, Bryant Megna, Oyedele Adeyi, Nicholas Lim   +3 more
doaj   +1 more source

Antigen-presenting cells and antigen presentation in tertiary lymphoid organs [PDF]

, 2016
Tertiary lymphoid organs (TLOs) form in territorialized niches of peripheral tissues characterized by the presence of antigens; however, little is known about mechanism(s) of antigen handling by ectopic lymphoid structures.
Bedaj, Marija, Benson, Robert A., Hughes, Catherine E., Maffia, Pasquale   +3 more
core   +1 more source

An interesting case of hemiplegia in a child

Annals of Indian Academy of Neurology, 2007
Hemiplegia in children occurs due to several causes. We report an interesting case who presented with prolonged fever, native valve endocarditis and infection triggered Macrophage activation syndrome.
Chandra Sadanandavalli, Syamlal S, Ravi Kavitha, Somarajan A, Suresh Krishnan   +4 more
doaj  

Macrophage centripetal migration drives spontaneous healing process after spinal cord injury. [PDF]

, 2019
Traumatic spinal cord injury (SCI) brings numerous inflammatory cells, including macrophages, from the circulating blood to lesions, but pathophysiological impact resulting from spatiotemporal dynamics of macrophages is unknown.
Edgerton, V Reggie, Hara, Masamitsu, Harimaya, Katsumi, Inoue, Kazuhide, Iwamoto, Yukihide, Kijima, Ken, Kobayakawa, Kazu, Kubota, Kensuke, Masuda, Takahiro, Matsumoto, Yoshihiro, Nakashima, Yasuharu, Ohkawa, Yasuyuki, Okada, Seiji, Ozato, Keiko, Saito, Takeyuki, Tamaru, Tetsuya, Tamura, Tomohiko, Tsuda, Makoto, Yokota, Kazuya, Yoshizaki, Shingo   +19 more
core   +1 more source

Epigenetics and immunometabolism in diabetes and aging [PDF]

, 2018
Significance: A strong relationship between hyperglycemia, impaired insulin pathway and cardiovascular disease in type 2 diabetes (T2D) is linked to oxidative stress and inflammation.
Cosentino, Francesco, Guzik, Tomasz J.
core   +2 more sources

Idiopathic Pulmonary Hemosiderosis in a Child with Recurrent Macrophage Activation Syndrome Secondary to Systemic Juvenile Idiopathic Arthritis

Case Reports in Pediatrics, 2017
Macrophage activation syndrome, a severe complication of systemic juvenile idiopathic arthritis and other inflammatory diseases, represents one of the most important rheumatological emergencies.
Kenan Barut, Sezgin Sahin, Amra Adrovic, Velat Sen, Ozgur Kasapcopur   +4 more
doaj   +1 more source

Macrophage activation syndrome, a rare complication of primary Sjögren’s syndrome: a case report

Journal of Medical Case Reports, 2019
Background The association of macrophage activation syndrome and primary Sjögren’s syndrome has been rarely reported in the literature. We report the first observation of this association in Africa, south of the Sahara, and we discuss the diagnosis and ...
B. S. Kane, M. Niasse, A. Faye, N. D. Diack, B. Djiba, M. Dieng, M. Sow, A. C. Ndao, N. Diagne, S. Ndongo, A. Pouye   +10 more
doaj   +1 more source

Deconvolution of pro- and antiviral genomic responses in Zika virus-infected and bystander macrophages. [PDF]

, 2018
Genome-wide investigations of host-pathogen interactions are often limited by analyses of mixed populations of infected and uninfected cells, which lower sensitivity and accuracy.
Benner, Christopher, Branche, Emilie, Carlin, Aaron F, Glass, Christopher K, Heinz, Sven, Ley, Klaus, Shresta, Sujan, Suarez-Amaran, Lester, Viramontes, Karla M, Vizcarra, Edward A   +9 more
core  

Downregulation of Mcl-1 has anti-inflammatory pro-resolution effects and enhances bacterial clearance from the lung [PDF]

, 2013
Phagocytes not only coordinate acute inflammation and host defense at mucosal sites, but also contribute to tissue damage. Respiratory infection causes a globally significant disease burden and frequently progresses to acute respiratory distress syndrome,
A Cross, A G Rossi, A Planaguma, AE Leitch, AE Leitch, AG Rossi, AL Alessandri, B Dibbert, BM Fournier, C Akgul, C D Lucas, C Haslett, C Nathan, C T Robb, CD Lucas, CN Serhan, D A Dorward, DA Dorward, DA Moulding, DA Moulding, DA Steimer, DJ Wardle, E Abraham, EE McGrath, GL Bannenberg, GS Worthen, H Liu, HG Folkesson, HM Marriott, I Dzhagalov St, I Nicoletti, J A Marwick, J Liang, JS Savill, K C Allen, K Ganeshan, KP Steinberg, L Fialkow, L Santo, M A Tait, MA Matthay, N Chiang, N Fotouhi-Ardakani, N Hirani, O Eickmeier, R Boxio, R Duffin, S Brode, S Fox, S Fox, S Michlewska, SJ Leuenroth, SL Poe, SP Garrison, T Hideshima, T Tanaka, TR Ulich, U Koedel, Y Liu   +58 more
core   +1 more source