Results 71 to 80 of about 551,256 (383)
Epigenetics and immunometabolism in diabetes and aging [PDF]
Significance: A strong relationship between hyperglycemia, impaired insulin pathway and cardiovascular disease in type 2 diabetes (T2D) is linked to oxidative stress and inflammation.
Cosentino, Francesco, Guzik, Tomasz J.
core +5 more sources
Chimeric antigen receptor (CAR) T cell–related HLH/MAS is an unusual manifestation of severe cytokine release syndrome (CRS) with poor prognosis and a challenging diagnosis.
R. M. Martín-Rojas+18 more
semanticscholar +1 more source
Non-Gaussianity and Dynamical Trapping in Locally Activated Random Walks [PDF]
We propose a minimal model of \emph{locally-activated diffusion}, in which the diffusion coefficient of a one-dimensional Brownian particle is modified in a prescribed way --- either increased or decreased --- upon each crossing of the origin. Such a local mobility decrease arises in the formation of atherosclerotic plaques due to diffusing macrophage ...
arxiv +1 more source
Neuroinflammation is a putative target for the prevention and treatment of perioperative neurocognitive disorders. [PDF]
IntroductionThe demographics of aging of the surgical population has increased the risk for perioperative neurocognitive disorders in which trauma-induced neuroinflammation plays a pivotal role.Sources of dataAfter determining the scope of the review ...
Lai, IK, Li, R, Maze, M, Saxena, S
core +2 more sources
Dissecting the heterogeneity of macrophage activation syndrome [PDF]
Methods Patient data were collected retrospectively by pediatric rheumatologists (PR) or pediatric hemato-oncologists (PHO). Clinical features, treatments and outcome were compared between groups by Mann-Whitney or chisquare tests. “Severe course” was defined as ICU admission or death.
Olga Vougiouka+37 more
openaire +2 more sources
Gastrointestinal system involvement characteristics in Covid -19 patients
Objective: To evaluate the involvement of gastrointestinal tract features in patients of coronavirus disease-2019, and to analyse the effects of these features on the development of critical illness, macrophage activation syndrome and mortalit Method:
Halil Atasoy, Vehbi Urcar
doaj +1 more source
Deep Learning-Based Quantification of Pulmonary Hemosiderophages in Cytology Slides [PDF]
Purpose: Exercise-induced pulmonary hemorrhage (EIPH) is a common syndrome in sport horses with negative impact on performance. Cytology of bronchoalveolar lavage fluid by use of a scoring system is considered the most sensitive diagnostic method. Macrophages are classified depending on the degree of cytoplasmic hemosiderin content.
arxiv +1 more source
Segmentation based tracking of cells in 2D+time microscopy images of macrophages [PDF]
The automated segmentation and tracking of macrophages during their migration are challenging tasks due to their dynamically changing shapes and motions. This paper proposes a new algorithm to achieve automatic cell tracking in time-lapse microscopy macrophage data.
arxiv +1 more source
Boosting autophagy in the diabetic heart: a translational perspective [PDF]
Diabetes, obesity, and dyslipidemia are main risk factors that promote the development of cardiovascular diseases. These metabolic abnormalities are frequently found to be associated together in a highly morbid clinical condition called metabolic ...
Boppana, V. Subbarao+4 more
core +1 more source
Systemic juvenile idiopathic arthritis (sJIA) is characterized by arthritis, fever, rash, lymphadenopathy, hepatosplenomegaly, and serositis. Macrophage activation syndrome is the most feared complication of sJIA with a high risk of mortality.
Nicole Davidson+5 more
doaj +1 more source